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Familial malignant blood disease in the county of Jämtland, Sweden

In a material of 942 patients with malignant hematological disease, encompassing all diagnosed cases in the county of Jämtland in Sweden during a 22‐yr period, 36 families with multiple cases of such disease were found. Approximately 5% of the patients have at least one close relative who also suffers from a malignant hematological disease. An especially strong familial occurrence was found in the

Towards a European health research and innovation cloud (HRIC)

The European Union (EU) initiative on the Digital Transformation of Health and Care (Digicare) aims to provide the conditions necessary for building a secure, flexible, and decentralized digital health infrastructure. Creating a European Health Research and Innovation Cloud (HRIC) within this environment should enable data sharing and analysis for health research across the EU, in compliance with

Adaptive Routing with Guaranteed Delay Bounds using Safe Reinforcement Learning

Time-critical networks require strict delay bounds on the transmission time of packets from source to destination. Routes for transmissions are usually statically determined, using knowledge about worst-case transmission times between nodes. This is generally a conservative method, that guarantees transmission times but does not provide any optimization for the typical case. In real networks, the

A five-axis parallel kinematic mirror unit for soft X-ray beamlines at MAX IV

With the introduction of the multi-bend achromats in the new fourth-generation storage rings the emittance has decreased by an order of magnitude resulting in increased brightness. However, the higher brightness comes with smaller beam sizes and narrower radiation cones. As a consequence, the requirements on mechanical stability regarding the beamline components increases. Here an innovative five-

Metabolomic Signature of Early Vascular Aging (EVA) in Hypertension

Arterial stiffening is a hallmark of early vascular aging (EVA) syndrome and an independent predictor of cardiovascular morbidity and mortality. In this case-control study we sought to identify plasma metabolites associated with EVA syndrome in the setting of hypertension. An untargeted metabolomic approach was used to identify plasma metabolites in an age-, BMI-, and sex-matched groups of EVA (n

Learning Based Model Predictive Control of Combustion Timing in Multi-Cylinder Partially Premixed Combustion Engine

Partially Premixed Combustion (PPC) has shown to be a promising advanced combustion mode for future engines in terms of efficiency and emission levels. The combustion timing should be suitably phased to realize high efficiency. However, a simple constant model based predictive controller is not sufficient for controlling the combustion during transient operation. This article proposed one learning

Analys av geografiska data

I detta kapitel i boken Geografisk information Behandling beskrivs och behandlas metoder för hur geografisk data analyseras. Kapitlet omfattar såväl geografisk teori som exempel på tillämpningar. Geografisk informationsbehandling baseras på insamling, lagring, analys och visualisering av geografiska data. Denna indelning utgör också grunden för bokens disposition. Boken är i första hand avsedd för

Inequality and Uneven Development in Ghana

This dissertation investigates the extent and evolution of income and educational inequality, as well as governments’ tax and expenditure policies and their implications for inequality in Ghana over the long-term. The results of the dissertation are presented in four-thematically related papers. Paper I uses a social tables approach to measure the extent of income inequality in colonial Ghana and