PARP16/ARTD15 is an intracellular mono-ADP-ribosyltransferase that catalyzes auto- and heteromodification by transfer of a single ADP-ribose moiety. It belongs to the ADP-ribosyltransferase (ART) superfamily. ADP-ribosylation of amino acids on protein targets is critical in the regulation of cellular pathways in eukaryotes, especially involved in physiological functions, cell stress responses and

Background: Children’s need for play is intertwined with health and development. For many children public playgrounds represent environments that are playful and important in developing good health. Without efforts to facilitate climate adaptation of outdoor playgrounds there may be a loss of health and well-being during childhood and their future lives. Purpose: To explore the reasoning and descr

A survey of nuclear structure results obtained along α-decay chains stemming from isotopes of element 114, Fl, and element 115, Mc, is presented. Measures taken to ensure a reliable hand-over of nuclear spectroscopy output to nuclear structure theory are outlined. Possible links between decay chains starting from element 117, Ts, and element 115, Mc, are commented on. The experiments were conducte

OBJECTIVES: To explore clustering of comorbidities among patients with a new diagnosis of osteoarthritis (OA) and estimate the 10-year mortality risk for each identified cluster.METHODS: This is a population-based cohort study of individuals with first incident diagnosis of OA of the hip, knee, ankle/foot, wrist/hand, or 'unspecified' site between 2006 and 2020, using SIDIAP (a primary care databa

Dendritic cells are the sentinels of the immune system, linking the innate and adaptive immune response. Myeloid and dendritic cell models have been successfully used in in vitro approaches to predict adverse outcomes such as skin sensitization. We here exposed a well-characterized human dendritic cell-like cell line to agricultural chemicals, including fungicide formulations, active ingredients,

Uppsatsen syftar till att undersöka hur stor möjlighet arbetsgivare på Sveriges arbetsplatser har att styra över sina anställdas utseenden i form av att uppställa utseendekrav samt klädkoder. Arbetsledningsrätten är långtgående i Sverige och ger arbetsgivare rätt att leda och fördela arbetet i sin verksamhet som det behagar dem. Även om arbetsledningsrätten är genomgripande är den inte obegränsad.The purpose of this essay is to establish the extent to which employers in Sweden's workplaces are able to regulate their employees' appearance through the implementation of dress codes and appearance rules. In Sweden, businesses have a fairly broad range of options for how they choose to organize and allocate work inside their organizations. Although the extensive labor management rights

Artificial lighting at nights (ALAN) affects behaviour in many animals, especially nocturnal species. However, its effect on frugivorous bats remains less explored, especially in the family Pteropodidae. Since they rely predominantly on vision and light-based cues, ALAN at roost sites could have consequences on their behaviour, activity, and the ecosystem services they provide. In a semi-urban sit

Objective: Meniscal calcifications are associated with the pathogenesis of knee osteoarthritis (OA). We propose a micro-computed tomography (μCT) based 3D analysis of meniscal calcifications ex vivo, including a new grading system. Method: Human medial and lateral menisci were obtained from 10 patients having total knee replacement for medial compartment OA and 10 deceased donors without knee OA (

The preparation of strongly emissive CsPbBr3 perovskite nanocrystals with robust surface passivation is a challenge in the field of lead halide perovskite nanomaterials. We report an approach to prepare polymer-capped CsPbBr3 perovskite nanocrystals by reacting oleylammonium/oleate-capped Cs4PbBr6 nanocrystals with poly(maleic anhydride-alt-1-octadecene) (PMAO). PMAO contains succinic anhydride un

Biometric signatures based on either the physiological or behavioural features of a person have been widely used for identification and authentication. However, few strategies have been developed that combine the two types of features in one signature. Here, we report a type of biometric signature based on the triboelectricity of the human body (TEHB) that combines these two types of features. Thi

Enteric neuropathy describes a disease of the bowel caused by anomalies in the enteric nervous system. Patients suffering from this disease have symptoms including nausea, vomiting, diarrhea and pain. As enteric neuropathy is not well understood yet, its diagnosis is a non-trivial task. Research on the enteric nervous system is needed in order to gain a better understanding of this disease, makin