The encapsulation of Pt and Au-based anticancer agents within a protein cage is a promising way to enhance the selectivity of these potential drugs. Here a cytotoxic organometallic compound containing platinum(II) and gold(I) has been encapsulated within a ferritin nanocage (AFt). Inductively plasma coupled mass spectrometry data, collected to evaluate the amount of Pt and Au within the cage, indi

I rättsfallet NJA 2024 s. 564 har Högsta domstolen avgjort ett mål rörandesexuellt ofredande. En lärare hade under en lektion yttrat ”oj vilka stora bröstdu fick nu” till sin femtonåriga elev. Uttalandet hade fällts i anslutning till attmålsäganden provat ett tyngdlyftarbälte. Högsta domstolen ogillade åtaleteftersom uttalandet visserligen hade varit opassande och olämpligt, men intekunde ”anses h

Small routines and ingrained cultural reflexes as well as micro-rituals form an often unnoticed or ignored flow in everyday life. They acquire their power by being taken for granted and embodied. In situations of conflict, crisis or change, they may suddenly be noticed and become problematic. This chapter looks at how moves, affect, sensations and stuff interact in the making and unmaking of routi

Mars has long been a source of inspiration, imagination and, lately, aspiration for many. It has generated a breadth of beliefs and ideas, as well as hope for a bright future there. However, the red planet will never offer a fresh start: we would carry with us some of our culture and our politics. Our future there would remain connected to Earth’s history, particularly human history. In the presen

Mars science fiction (SF) has interacted with Mars science ever since the advent of modern science, and has largely influenced public perceptions of the red planet and its exploration. In this chapter, it is argued that it has not only shaped numerous (mis)conceptions about the possibilities of indigenous Martian life, eventual human settlement and its challenges, but that it also has a large outr

The aim of this study was to explore how people with impairments perceived the accessibility of information regarding the COVID-19 pandemic in Sweden and what improvements they suggest to ensure accessibility of information in future societal crises. The study had a descriptive design, involving interviews and focus group discussions with people with impairments and their representative organisati

Food packaging is one of the most important strategies to prevent food damage or spoilage during storage and the supply chain. Among various food types, seafood, a high-value product, is particularly vulnerable to post-harvest quality loss and microbial contamination during storage. Although current plastic-based packaging materials are durable, they pose a serious threat to the environment. There

Background: The Organ Care System and Non-ischemic Heart Preservation methods have emerged as significant advancements in heart transplantation, designed to mitigate ischemic injury and extend preservation times. However, their high costs and logistical complexities necessitate strategic utilization. Methods: We evaluated data from 83,761 heart transplants registered in the International Society f

Abstract: Background/Objectives: Vitamin K-dependent proteins (VKDPs) all commonlypossess specially modified γ-carboxyglutamic acid residues created in a vitaminK-dependent manner. Several liver-derived coagulation factors are well characterisedVKDPs. However, much less is known about extrahepatic VKDPs, which are more diversein their molecular structures and functions, and some of which have beenBackground/Objectives: Vitamin K-dependent proteins (VKDPs) all commonly possess specially modified γ-carboxyglutamic acid residues created in a vitamin K-dependent manner. Several liver-derived coagulation factors are well characterised VKDPs. However, much less is known about extrahepatic VKDPs, which are more diverse in their molecular structures and functions, and some of which have been impli

Working from anywhere, often associated with digital nomadism, is a growing trend that blurs the boundaries between work and leisure, with individuals choosing to work from tourist destinations. The phenomenon has caught the attention of academics, who mainly focus on the lifestyle aspects of digital nomadism. However, destination management organizations, as well as the tourism and hospitality in

The main section of this chapter describes vowel harmony (VH) in Khalkha Mongolian, which has both tongue-root harmony and rounding harmony. The vowels are divided into two classes, retracted tongue root (RTR), a, ?, ?, and advanced tongue root (ATR), e, o, u, while i is neutral. There is rich inflectional and derivational morphology based on suffixes, whose vowels alternate with the harmony class

Whether developed or less developed, all countries need skilled mental labor (SML) to use technologies effectively and to attain economic growth and development. Without appropriate SML, no country can make the best use of its firms and institutions. Time and investment are required for an individual to become a skilled mental laborer, but these are not sufficient. The training must be at a level

Body dysmorphic disorder (BDD) is an obsessive–compulsive disorder-related psychiatric condition characterized by an intense preoccupation with perceived physical flaws that are not observable by others. BDD affects ~2% of the adult population but is underdiagnosed, partly owing to limited clinician awareness, and undertreated, partly due to limited access to treatment. Research on the aetiology o

Background: Supplier involvement in product development has proven beneficial for companies and is a phenomenon researched in various domains. The definitions of supplier involvement represent points of origin and dimensions addressed in research. Still, there is no overview of these definitions and dimensions. This study reviews current definitions of the phenomenon of supplier involvement in pro

Background: The Abdominal Compartment Society (WSACS) established consensus definitions and recommendations for the management of intra-abdominal hypertension (IAH) and abdominal compartment syndrome (ACS) in 2006, and they were last updated in 2013. The WSACS conducted an international survey between 2022 and 2023 to seek the agreement of healthcare practitioners (HCPs) worldwide on current and n

Aims: The purpose of this study was to address the need to improve opportunities for patient participation in their health and health services. This paper reports if and how patients' preferences matched their experiences of participation in treatment for hypertension in primary healthcare and what factors were linked with having had opportunities for participation that matched one's preferences.

Aims: Among patients with myocardial infarction (MI) with preserved left ventricular ejection fraction (LVEF), the REDUCE-AMI trial did not demonstrate a benefit of beta-blocker vs. no beta-blocker treatment on all-cause mortality and recurrent myocardial infarction. The aim of this pre-specified sub-study was to investigate effects of beta-blockers on self-reported symptoms of anxiety and depress

Modern hydrological modeling frequently incorporates global remote sensing or reanalysis products for multivariate calibration. Although these datasets significantly contribute to model accuracy, the inherent uncertainties in the datasets and multivariate calibration present challenges in the modeling process. To address this issue, this study introduces an adaptive, process-wise fitting framework

The hemodynamic definitions of pulmonary hypertension consider resistive loading (pulmonary vascular resistance [PVR]), but there are increasing evidence that pulsatile loading (pulmonary artery compliance [PAC]) has functional and prognostic importance. The aims of the present study on patients with left heart disease, were to evaluate a novel echocardiographic right ventricular (RV) afterload sc