BACKGROUND: Malignant mesothelioma (MM) is a therapy-resistant tumor, often causing an effusion. Drugs targeting the programmed cell death 1 (PD-1)/programmed cell death ligand 1 (PD-L1) pathway have shown promising results, but assessment of PD-L1 expression to select patients for therapy has mainly been performed on histologic tissue samples. In a previous study, we showed that MM effusions are

Three-dimensional growth of nanostructures can be used to reduce the threading dislocation density that degrades III-nitride laser performance. Here, nanowire-based hexagonal GaN microprisms with flat top and bottom c-facets are embedded between two dielectric distributed Bragg reflectors to create dislocation-free vertical optical cavities. The cavities are electron beam pumped, and the quality (

Background: Controlled release (CR) systems have emerged as powerful platforms for innovative formulations and dietary designs to enhance the techno-functional performance of bioactive food ingredients both in human body and food products. Generally, the term CR, has developed to indicate delivery systems with optimal control over release rate and performance. However, there are principles and req

Vem bestämmer när det är läggdags? Titeln på Glenn Möllergrenskapitel anspelar på den anpassning som gäller för många äldre hemtjänstmottagare. Möllergren går igenom kommunala riktlinjer förhemtjänst och konstaterar att nästan alla handlar om ”basala behov”medan sådant som deltagande i politik, kultur, idrott och föreningsliv,som är en självklarhet för många av oss, tycks hamna utanför det somingå

Jordan has one of the lowest available water supplies in the world; meanwhile, Jordan has seen a large increase in population and refugee’s fluxes, leading to an increase in water demand. To address this unprecedented water scarcity, Jordan’s water must be used where its social and economic value is highest. Jordan must treat and reuse virtually every drop of water. With using brackish water (i.e,

For many fleeing their home countries, destinations in northern Europe were the ultimate goal. But what happened when they got there?

I argue that reception history can have a, limited but important, role to play as tie- breaker in the evaluation of reconstructions of historical philosophical arguments and positions. In an effort to exemplify the proposed methodology I argue that Lisa Shapiro’s rational reconstruction of Descartes’s provisional moral code in terms of a broad conception of morality supplies us with an interpretat

BACKGROUND: The exchange of cerebrospinal (CSF) and interstitial fluid is believed to be vital for waste clearance in the brain. The sleep-dependent glymphatic system, which is comprised of perivascular flow of CSF and is largely dependent on arterial pulsatility and astrocytic aquaporin-4 (AQP4) expression, facilitates much of this brain clearance. During the last decade, several observations hav