Sökresultat

Filtyp

Din sökning på "*" gav 525885 sökträffar

Analysis of DFT-based channel estimators for OFDM

In this paper we analyze the performance of three low-complexity channel estimators, based on the discrete Fourier transform (DFT), for orthogonal frequency-division multiplexing (OFDM) systems. Estimators of this type have been analyzed for discrete-time channels, and we extend this analysis to continuous-time channels. We present analytical expressions for their mean-squared error (MSE) and eval

Possible human leukocyte antigen-mediated genetic interaction between type 1 and type 2 Diabetes

We assessed the prevalence of families with both type 1 and type 2 diabetes in Finland; and we studied, in patients with type 2 diabetes, the association between a family history of type 1 diabetes, glutamic acid decarboxylase (GAD) antibodies (GADab), and type 1 diabetes-associated human leukocyte antigen (HLA) DQB1-genotypes. Further, in mixed type 1/type 2 diabetes families, we investigated whe

Predictive markers for tamoxifen response in primary breast cancer

Popular Abstract in Swedish Bröstcancer är den vanligaste cancersjukdomen hos kvinnor i västvärlden och årligen nydiagnosticeras omkring 7000 patienter, bara i Sverige. Antalet nyinsjuknade ökar för varje år medan dödligheten sjunker och de främsta orsakerna till detta tros vara förbättrad diagnostik via mammografiscreening och nya behandlingsmöjligheter. Bröstcancer behandlas primärt med kirurgi,It is well-known that a majority of breast cancers are hormone-dependent, making endocrine therapy an important adjuvant treatment after surgery. Susceptibility to endocrine treatment is determined by the presence of estrogen receptors (ER) and progesterone receptors (PR) in the tumors. Tamoxifen is the most well-established endocrine treatment available, inhibiting tumor growth and improving surv

Seasonality extraction by function fitting to time-series of satellite sensor data

A new method for extracting seasonality information from time-series of satellite sensor data is presented. The method is based on nonlinear least squares fits of asymmetric Gaussian model functions to the time-series. The smooth model functions are then used for defining key seasonality parameters, such as the number of growing seasons, the beginning and end of the seasons, and the rates of growt

A web-based interactive virtual environment for mobile phone customization

With globalization, more and more companies are becoming multisited. Efficient and timely collaboration and communication among the development team members become critical for product success. This paper proposes a web-based virtual environment for mobile phone customization, named VMPDS (Virtual Mobile Phone Design Space). The features of this system include the combination of web technology and

Long-term exposure to glucose and lipids inhibits glucose-induced insulin secretion downstream of granule fusion with plasma membrane.

Mouse beta-cells cultured at 15 mmol/l glucose for 72 h had reduced ATP-sensitive K+ (K-ATP) channel activity (-30%), increased voltage-gated Ca2+ currents, higher intracellular free Ca2+ concentration ([Ca-i(2+]) +160%), more exocytosis (monitored by capacitance measurements, +100%), and greater insulin content (+230%) than those cultured at 4.5 mmol/l glucose. However, they released 20% less ins

A novel interaction between type IV pili of Neisseria gonorrhoeae and the human complement regulator C4B-binding protein

C4b-binding protein (C4BP) is an important plasma inhibitor of the classical pathway of complement activation. Several bacterial pathogens bind C4BP, which may contribute to their virulence. In the present report we demonstrate that isolated type IV pili from Neisseria gonorrhoeae bind human C4BP in a dose-dependent and saturable manner. C4BP consists of seven identical alpha-chains and one beta-c

Phomopsidone, a novel depsidone from an endophyte of the medicinal plant Eupatorium arnottianum

The medicinal plant Eupatorium arnottianum can be found in the Northeast and center of Argentina and the South of Bolivia. From plant material collected in Argentina an endophytic Phomopsis was isolated. The fungus was identified by microscopic features and analysis of its ITS sequence. Cultures yielded, besides mellein and nectriapyrone, a novel depsidone derivative for which we propose the name

A new general-purpose isothermal microcalorimeter for use at temperatures up to 200 degrees C

The design and some properties of a new general-purpose isothermal microcalorimeter are reported. The instrument is a twin thermopile heat conduction calorimeter, which is designed for use up to 200 degreesC. The calorimetric units and surrounding heat sink are suspended inside a hollow aluminium construction, which is thermostated. Above that unit a second thermostated block is positioned and the

Studies of Mesenchymal Progenitor Cells and Tumour Growth, Integrins and Matrix Metalloproteinases

In this thesis we characterize the effect of mesenchymal progenitor cells (MPCs) on tumour growth, and show that MPCs can have inhibitory effects on tumour development. We developed a method to subcutaneously transplant tumour cells, cultured in vitro in a pre-formed gelatin matrix, that made it possible to study the early phases of tumour development. Using this method we inoculated rats with gel

A randomised RSA study of Peri-apatite((TM)) HA coating of a knee prosthesis

Fifty knees scheduled for a total knee prosthesis were randomized in two groups. Both groups had a noncemented fixation of the porous-coated implants but one group received a prosthesis with ceramic coating on the porous surface of the implant. The knees were evaluated with RSA technique regarding micromotion the first two years. There were less micromotion in the coated group. The results indicat

Early TCR alpha beta expression promotes maturation of T cells expressing Fc epsilon RI gamma containing TCR/CD3 complexes

In a previous study we presented data indicating that the expanded population of CD4(-)CD8(-) (DN) alphabeta T cells in TCRalpha-chain-transgenic mice was partially if not entirely derived from gammadelta T cell lineage cells. The development of both gammadelta T cells and DN alphabeta T cells is poorly understood; therefore, we thought it would be important to identify the immediate precursors of