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RIFM fragrance ingredient safety assessment, p-t-butyl-α-methylhydrocinnamic aldehyde, CAS Registry Number 80-54-6
New constraints on the evolution of 87Sr/86Sr of seawater during the Upper Triassic
The Late Triassic time interval witnessed several important biological turnovers, extinctions and onset of new life forms. Therefore, it is crucial to better constrain the tectonic, climatic and oceanographic framework at this time. The radiogenic strontium isotopic composition (87Sr/86Sr) of seawater, recorded in marine carbonates is sensitive to variations in continental weathering and oceanic s
Masters writing the rules: how peasant farmer MPs in the Swedish Estate Diet understood servants’ labour and the labour laws, 1823–1863
Peasant farmers made up one of the four estates in the Swedish parliament, the Diet of the four estates, from late medieval times up until the introduction of the two-chamber parliament in 1867. Affiliation to the estate of the peasant farmers was based on landholding. Landholding also entitled peasant farmers to employ servants. Peasant farmers thus played a double role: as masters of servants an
“Short” or “long” Rhaetian ? Astronomical calibration of Austrian key sections
The establishment of the Late Triassic time scale has given rise to considerable controversy, particularly regarding the Rhaetian duration and the inferred absolute age models. In this respect the astronomical polarity time scale (APTS) established from the continental successions of the Newark Basin (eastern North America) is considered as a reference record, although its completeness is question
A socio-psychological conceptualisation of overtourism
Tourist pressure on local populations, also termed ‘overtourism’, has received much attention in the global media, as tensions related to social, economic or environmental change have grown in many destinations. While protests against tourists and tourism development have existed for decades, these are now often more organised, vocal, and politically active. As a phenomenon associated with residen
Risk concentration under second order regular variation
Measures of risk concentration and their asymptotic behavior for portfolios with heavy-tailed risk factors is of interest in risk management. Second order regular variation is a structural assumption often imposed on such risk factors to study their convergence rates. In this paper, we provide the asymptotic rate of convergence of the measure of risk concentration for a portfolio of heavy-tailed r
Self-efficacy, recovery and psychological wellbeing one to five years after heart transplantation : a Swedish cross-sectional study
Background: Self-efficacy refers to a person´s confidence in carrying out treatment-related activities and constitutes the foundation of self-management as well as long-term follow-up after heart transplantation. Exploring the heart recipients´ experiences by means of self-report instruments provides healthcare professionals with valuable information on how to supply self-management support after
Letter to the Editor : Cultural Barriers for Women in Surgery: How Thick is the Glass Ceiling? An Analysis from a Low-/Middle-Income Country
Lunar synchronization of daily activity patterns in a crepuscular avian insectivore
Biological rhythms of nearly all animals on earth are synchronized with natural light and are aligned to day-and-night transitions. Here, we test the hypothesis that the lunar cycle affects the nocturnal flight activity of European Nightjars (Caprimulgus europaeus). We describe daily activity patterns of individuals from three different countries across a wide geographic area, during two discrete
Coulomb Excitation of Proton-rich N = 80 Isotones at HIE-ISOLDE
A projectile Coulomb-excitation experiment was performed at the radioactive ion beam facility HIE-ISOLDE at CERN. The radioactive 140Nd and 142Sm ions were post accelerated to the energy of 4.62 MeV/A and impinged on a 1.45 mg/cm2-thin 208Pb target. The γ rays depopulating the Coulomb-excited states were recorded by the HPGe-array MINIBALL. The scattered charged particles were detected by a double
The Impact of Parental Diabetes on the Prevalence of Childhood Obesity
Background: Obesity among children and adolescents is a worldwide public health concern. Type 1 diabetes (T1D) and type 2 diabetes (T2D) incidence are increasing, with heredity and socioeconomic status as possible risk factors. How these factors affect the risk of childhood obesity remains unclear. The aim of this study was to investigate the association between obesity and parental diabetes among
Regulation of IRS-1, insulin signaling and glucose uptake by miR-143/145 in vascular smooth muscle cells
Regulation of insulin signaling by microRNAs in smooth muscle cells may contribute to diabetic vascular disease. The two smooth muscle enriched miRNAs miR-143 and miR-145 have been reported to target mediators of insulin signaling in non-smooth muscle cells. In this study, we aimed to determine the importance of this regulation in vascular smooth muscle cells, where expression of miR-143/145 is mu
Poor psychological health and 5-year suicide mortality : A population-based prospective cohort study
Objective: The objective was to investigate associations between the General Health Questionnaire with twelve sub-items (GHQ-12) and prospective five-year suicide mortality. The two commonly used GHQ-12 cut-offs (2/3 and 3/4) were analyzed. Method: The 2008 public health survey, which was conducted in the autumn of 2008 in Scania, southern Sweden, is based on a postal questionnaire answered by 28,
Relationship of Estimated GFR and Albuminuria to Concurrent Laboratory Abnormalities: An Individual Participant Data Meta-analysis in a Global Consortium
Rationale & Objective: Chronic kidney disease (CKD) is complicated by abnormalities that reflect disruption in filtration, tubular, and endocrine functions of the kidney. Our aim was to explore the relationship of specific laboratory result abnormalities and hypertension with the estimated glomerular filtration rate (eGFR) and albuminuria CKD staging framework. Study Design: Cross-sectional in
Efficient production of HPV16 E2 protein from HPV16 late mRNAs spliced from SD880 to SA2709
Human papillomaviruses (HPVs) produce a large number of alternatively spliced mRNAs, including a number of differently spliced mRNAs with the potential to produce E2 protein. To identify the alternatively spliced HPV16 mRNA with the highest ability to produce E2 protein, we have generated E2 cDNA expression plasmids representing the most common, alternatively spliced E2 mRNAs, and assessed their t
Numerical studies of gas-liquid Taylor flows in vertical capillaries using CuO/water nanofluids
Heat transfer and pressure drop characteristics of gas-liquid Taylor flows in a mini tube with 1 mm inner tube diameter were investigated numerically using a moving frame of reference method. A CuO/water nanofluid was used as the continuous phase, while nitrogen was adopted as the dispersed phase. The inlet Reynolds number ranged from 250 to 600, and the volume concentration of the CuO particles w
Fluorene exposure among PAH-exposed workers is associated with epigenetic markers related to lung cancer
OBJECTIVES: Exposure to high-molecular-weight polycyclic aromatic hydrocarbons (PAHs) may cause cancer in chimney sweeps and creosote-exposed workers, however, knowledge about exposure to low-molecular-weight PAHs in relation to cancer risk is limited. In this study, we aimed to investigate occupational exposure to the low-molecular-weight PAHs phenanthrene and fluorene in relation to different ca
Experiences and Management of Incidents That Influence Sleep in Patients With Cardiovascular Disease and Insomnia
BACKGROUND: Insomnia is a global problem and an important risk factor for patients living with cardiovascular disease (CVD), causing poor well-being and worsening disease prognosis. Yet, there is a lack of effective intervention strategies targeting sleep problems. To deliver patient-centered interventions and achieve good quality of sleep for this group, the own experiences of patients with CVD n
Entrepreneurial ecosystems : towards a systemic approach to entrepreneurship?
Despite its relative newness, entrepreneurial ecosystems (EEs) have attracted much attention from research and policy but they are recognized to be largely untheorized. It is claimed that one aspect which distinguishes the EE perspective from other perspectives related to business environments is its systemic approach; however, much of the systemic approach still needs to be investigated. The aim