Sökresultat

Filtyp

Din sökning på "*" gav 535696 sökträffar

Applying genetic technologies to combat infectious diseases in aquaculture

Disease and parasitism cause major welfare, environmental and economic concerns for global aquaculture. In this review, we examine the status and potential of technologies that exploit genetic variation in host resistance to tackle this problem. We argue that there is an urgent need to improve understanding of the genetic mechanisms involved, leading to the development of tools that can be applied

Measuring misophonia in youth: A psychometric evaluation of child and parent measures

BackgroundMisophonia is characterized by intense emotional reactions to specific sounds or visual stimuli and typically onsets during childhood. An obstacle for research and clinical practice is that no comprehensively evaluated measures for pediatric misophonia exist.MethodsIn a sample of 102 youth meeting the proposed diagnostic criteria of misophonia, we evaluated the child and parent-proxy ver

Psychotic Vulnerability and its Associations with Clinical Characteristics in Adolescents with Obsessive-Compulsive Disorder

Compared to peers, children and adolescents with obsessive-compulsive disorder (OCD) are at increased risk of developing psychotic disorders. Yet very few studies have examined early indicators of psychosis in pediatric OCD. In the present study, 52 youth with a primary diagnosis of OCD (Mage = 15.66 [SD = 2.33], 59.6% girls) were interviewed using the Schizophrenia Proneness Instrument Child and

Ending fossil-based growth: Confronting the political economy of petrochemical plastics

The expanding petrochemical industry depends on fossil fuels both as feedstock and a source of energy and is at the heart of the intertwined global crises relating to plastics, climate, and toxic emissions. Addressing these crises requires uprooting the deep-seated lock-ins that sustain petrochemical plastics. This perspective identifies lock-ins that stand in the way of ambitious emission reducti

Glucocorticoid-mediated induction of ZBTB16 affects insulin secretion in human islets and EndoC-βH1 β-cells

Glucocorticoid use is associated with steroid-induced diabetes mellitus and impaired pancreatic β-cell insulin secretion. Here, the glucocorticoid-mediated transcriptomic changes in human pancreatic islets and the human insulin-secreting EndoC-βH1 cells were investigated to uncover genes involved in β-cell steroid stress-response processes. Bioinformatics analysis revealed glucocorticoids to exert

Alkali-stable polybenzimidazole anion exchange membranes tethered with N,N-dimethylpiperidinium cations for dilute aqueous KOH fed water electrolyzers

Polybenzimidazole (PBI) is currently considered as a membrane material for alkaline water electrolyzers (AWEs), and has to be fed with highly concentrated aqueous KOH electrolytes in order to ensure sufficient electrolyte uptake and conductivity. However, the harsh operating conditions significantly limit the lifetime of PBI membranes. In response, we here report on the synthesis and performance o

Economic Preferences and Personality Traits Among Finance Professionals and the General Population : Characteristics of Finance Professionals

Based on artefactual field experiments, we investigate whether finance professionals differ from a sample of the working population in terms of industry-relevant preferences and personality traits. When adjusting for socioeconomic characteristics, we find only few and less marked differences: finance professionals are less risk averse, less trustworthy, show higher levels of psychopathy and are mo

Sample preparation effect on measured rheological properties of bitumen using Dynamic Shear Rheometer

Through improved bitumen characterization, which will increase the road'sdurability, stability, and performance, pavement engineering can apply thesustainability notion that should be followed in all disciplines nowadays. The newtechniques distinguish between the rheological properties of bituminous binders as a function of loading time and temperature to depict real-world behavior rather than onl

Complementary Pathways as “Genuine and Effective Access to Means of Legal Entry” in the Reasoning of the European Court of Human Rights

Complementary pathways are often viewed as an entirely political matter. While there is no legal obligation for states to introduce such, this article shows that their presence or absence has a bearing on how the ECtHR assesses compliance with the prohibition of collective expulsion of aliens. This concrete interaction between complementary pathways and human rights law has been introduced through

Understanding the spatial non-stationarity in the relationships between malaria incidence and environmental risk factors using Geographically Weighted Random Forest : A case study in Rwanda

As found in the health studies literature, the levels of climate association between epidemiological diseases have been found to vary across regions. Therefore, it seems reasonable to allow for the possibility that relationships might vary spatially within regions. We implemented the geographically weighted random forest (GWRF) machine learning method to analyze ecological disease patterns caused

Impact on Health-Related quality of life after wearing compression garment or not for six months in women with mild breast cancer-related arm lymphedema. A cross-sectional study

Background: Women with mild breast cancer-related arm lymphedema (BCRAL) mostly receive treatment with compression garments and instructions in self-care to prevent the progression of lymphedema. However, wearing a compression garment may be experienced as negative and may affect health-related quality of life (HRQOL) more than the lymphedema itself. The aim of this study was to investigate if the

Re-irradiation in Paediatric Tumours of the Central Nervous System : National Guidelines from the Swedish Workgroup of Paediatric Radiotherapy

There is a lack of clinical protocols for re-irradiation in paediatric central nervous system (CNS) tumours. To fill this void, the Swedish Workgroup of Paediatric Radiotherapy (SBRTG) compiled national guidelines on re-irradiation in paediatric CNS tumours (diffuse intrinsic pontine glioma, ependymoma, germinoma and medulloblastoma). These have been in clinical practice since 2019 in all paediatr

The Puzzling Royal Society Report on Covid-19

The Royal Society’s results exaggerated the efficacy of mandated lockdowns.A recent Royal Society report on the Covid-19 pandemic produced by a team led by Mark Walport, a professor of medicine at Imperial College London, captivated the press. The report concludes that non-pharmaceutical interventions (NPIs), including mandatory lockdowns, “can provide powerful, effective and prolonged reductions

Three-dimensional spatial mapping of the human hematopoietic microenvironment in healthy and diseased bone marrow

The bone marrow hematopoietic microenvironment (HME) plays a pivotal role in regulating normal and diseased hematopoiesis. However, the spatial organization of the human HME has not been thoroughly investigated yet. Therefore, we developed a three-dimensional (3D) immunofluorescence model to analyze changes in the cellular architecture in control and diseased bone marrows (BMs). BM biopsies from p

Risk Factors for Postoperative Complications Following Resection of Colorectal Liver Metastases and the Impact on Long-Term Survival : A Population-Based National Cohort Study

Background: Postoperative complications (POCs) following resection of colorectal liver metastases (CRLM) are common. The objective of this study was to evaluate risk factors for developing complications and their impact on survival considering prognostic factors of the primary tumor, metastatic pattern and treatment in a well-defined national cohort. Methods: Patients treated with resection for CR