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The dung beetle dance: an orientation behaviour?

An interesting feature of dung beetle behaviour is that once they have formed a piece of dung into a ball, they roll it along a straight path away from the dung pile. This straight-line orientation ensures that the beetles depart along the most direct route, guaranteeing that they will not return to the intense competition (from other beetles) that occurs near the dung pile. Before rolling a new b

Utility Analysis and Integration Model

The utility analysis and integration model is a proposed business reference model that offers a structured framework to help utilities succeed on the enterprise level by facilitating the coordination and integration of people, process, and technology.

In the name of king, country, and people on the Westminster model and Bhutan's constitutional transition

In 2008 Bhutan inaugurated a written constitution thereby instituting the state as a constitutional monarchy. The constitution is almost unanimously described as democratic by international media and academics. The ease with which this apparent consensus on its democratic character has been achieved, however, raises the important question of how best to approach the theory of constitutional democr

The potential use of DNA methylation biomarkers to identify risk and progression of type 2 diabetes.

Type 2 diabetes mellitus (T2D) is a slowly progressive disease that can be postponed or even avoided through lifestyle changes. Recent data demonstrate highly significant correlations between DNA methylation and the most important risk factors of T2D, including age and body mass index, in blood and human tissues relevant to insulin resistance and T2D. Also, T2D patients and individuals with increa

Molecular design of recombinant scFv antibodies for site-specific photocoupling to β-cyclodextrin in solution and onto solid support.

The ability to design and tailor-make antibodies to meet the biophysical demands required by the vast range of current and future antibody-based applications within biotechnology and biomedicine will be essential. In this proof-of-concept study, we have for the first time tailored human recombinant scFv antibodies for site-specific photocoupling through the use of an unnatural amino acid (UAA) and

Standalone vertex finding in the ATLAS muon spectrometer

A dedicated reconstruction algorithm to find decay vertices in the ATLAS muon spectrometer is presented. The algorithm searches the region just upstream of or inside the muon spectrometer volume for multi-particle vertices that originate from the decay of particles with long decay paths. The performance of the algorithm is evaluated using both a sample of simulated Higgs boson events, in which the

MicroRNA-7a regulates pancreatic beta cell function

Dysfunctional microRNA (miRNA) networks contribute to inappropriate responses following pathological stress and are the underlying cause of several disease conditions. In pancreatic beta cells, miRNAs have been largely unstudied and little is known about how specific miRNAs regulate glucose-stimulated insulin secretion (GSIS) or impact the adaptation of beta cell function to metabolic stress. In t

Phenomenological modeling of viscous electrostrictive polymers

A common usage for electroactive polymers (EAPs) is in different types of actuators, where advantage is taken of the deformation of the polymer due to an electric field. It turns out that time-dependent effects are present in these applications. One of these effects is the viscoelastic behavior of the polymer material. In view of the modeling and simulation of applications for EAP within a continu

Physical benefits of expanded physical education in primary school: findings from a 3-year intervention study in Sweden

The aim of this study was to assess whether a school-based program with expanded physical education lessons was effective in increasing children's physical capacity and in preventing excessive weight gain in children. The study performed in 2000-2003 comprised 132 children, 73 boys and 59 girls at baseline 6-9 years and in follow-up 9-12 years, attending two different schools with a similar size,

Ecological Regime Shifts in Lake Kälksjön, Sweden, in Response to Abrupt Climate Change Around the 8.2 ka Cooling Event

A detailed diatom record from Lake Kälksjön, west-central Sweden, reveals two periods of abrupt ecological change correlative with the 8.2 ka cooling event. Using a combination of abrupt step changes and piece-wise linear regressions, the diatom data were analysed for change points over time, and two sudden and large events that are described as regime shifts were detected. During the first event

From sneeze to wheeze: Non-invasive studies on asthma and rhinitis

Asthma and allergic rhinitis are diseases that cause major disability and illness in all ethnic groups and ages. It is well established that allergic rhinitis and asthma are closely linked entities and more than 75 % of the patients with asthma reports concomitant rhinitis. Asthma is also closely associated to bronchial hyperresponsiveness, and a large part of patients with rhinitis alone show a r

Cluster headache and parietal glioblastoma multiforme.

INTRODUCTION: Cluster headache (CH) is a primary headache by definition not caused by any known underlying structural pathology. However, symptomatic cases have been described. The evaluation of CH is an issue unresolved. CASE REPORT: A 41-year-old man presented with a 3-month history of side-locked attacks of excruciating severe stabbing and boring right-sided pain located in the temple and the

Multiple Path-Dependent Routes for Phase-Transition Kinetics in Thermoresponsive and Field-Responsive Ultrasoft Colloids

The nature of solid-solid phase transformations has been a long-standing question spanning the fields of metallurgy and condensed-matter physics, with applications from metallic alloys and ceramics to modern shape-memory materials. In spite of the importance of solid-to-solid transformations in many areas of materials science and condensed-matter physics and the numerous experimental and theoretic

Viewpoints of adults with and without Autism Spectrum Disorders on public transport

Background: Public transport is low cost, allows for independence, and facilitates engagement and participation for non-drivers. However, the viewpoints of individuals with cognitive disabilities are rarely considered. In Australia, the prevalence of Autism Spectrum Disorders (ASD) is approximately 1% and increasing. Many individuals with ASD do not possess a driver's licence, indicating that acce

The Usefulness of Negative Valve Overlap for Gasoline Partially Premixed Combustion, PPC

Partially premixed combustion has the potential of high efficiency and simultaneous low soot and NOx emissions. Running the engine in PPC mode with high octane number fuels has the advantage of a longer premix period of fuel and air which reduces soot emissions, even at higher loads. The problem is the ignitability at low load and idle operating conditions. The objective is to investigate the use

Synthesis of C-1 indol-3-yl substituted tetrahydroisoquinoline derivatives via a Pictet-Spengler approach

A protocol for the diastereoselective synthesis of C-1 indol-3-yl substituted tetrahydroisoquinoline derivatives via Pictet-Spengler condensation with L-DOPA or L-DOPA derivatives and 1H-indole-3-carbaldehydes is presented. The protocol is used for the successful synthesis of several tetrahydroisoquinolines as well as diketopiperazine fused analogues. (C) 2012 Elsevier Ltd. All rights reserved.