Stretch-dependent smooth muscledifferentiation in theportal vein - role of actin polymerization, calcium signaling and microRNAs.
The mechanical forces acting onsmooth muscle cells in the vascular wall are known to regulate processes such as vascular remodeling and contractile differentiation. However, investigations to elucidate the underlying mechanisms of mechanotransduction in smooth muscle have been hampered by technical limitations associated with mechanical studies on pressurized small arteries, due primarily to the s