The differential invariant yield as a function of transverse momentum (pT) of electrons from semileptonic heavy-flavour hadron decays was measured at midrapidity in central (0–10%), semi-central (30–50%) and peripheral (60–80%) lead–lead (Pb–Pb) collisions at sNN=5.02 TeV in the pT intervals 0.5–26 GeV/c (0–10% and 30–50%) and 0.5–10 GeV/c (60–80%). The production cross section in proton–proton (p

Objective: We hypothesized that morphine has a depressing effect on early brain activity, assessed using quantitative aEEG/EEG parameter and depressed activity will be associated with brain volumes at term in extremely preterm infants. Study design: 174 preterm infants were enrolled in 3 European tertiary NICUs (mean GA:26 ± 1wks) and monitored during the first 72 h after birth with continuous 2 c

Although natural products are an important source of drugs and drug leads, identification and validation of their target proteins have proven difficult. Here, we report the development of a systematic strategy for target identification and validation employing drug affinity responsive target stability (DARTS) and mass spectrometry imaging (MSI) without modifying or labeling natural compounds. Thro

This paper reports on CFD simulations of in-cylinder flow and combustion in an open-bowl heavy duty diesel engine at high load. The focus of the study is to unravel the effect of swirl motion on the soot formation and on the late cycle soot oxidation. To incorporate detailed kinetic mechanism while maintaining a manageable computational time, Representative Interactive Flamelets (RIF) method is em

An acoustically levitated droplet has been used to collect synchrotron SAXS data on human serum albumin protein solutions up to a protein concentration of 400mgml-1. A careful selection of experiments allows for fast data collection of a large amount of data, spanning a protein concentration/solvent concentration space with limited sample consumption (down to 3μL per experiment) and few measuremen

We present 783 surgical resections of typical and atypical carcinoid tumors of the lung identified in the pathology files of 20 different pathology departments. All cases were critically reviewed for clinical and pathological features and further correlated with clinical outcomes. Long-term follow-up was obtained in all the patients and statistically analyzed to determine significance of the diffe

OBJECTIVES: Infantile hemangiomas (IHs) are common; some cases require timely referral and treatment to prevent complications. We developed and validated a reliable instrument for timely and adequate referral of patients with IH to experts by nonexpert primary physicians. METHODS: In this multicenter, cross-sectional, observational study, we used a 3-stage process: (1) development of the Infantile

Background: Victimisation of women is encountered in all countries across the world, it damages the mental and physical health of women. During pregnancy and the postpartum period, women are at a greater risk of experiencing violence from an intimate partner. The aim of this study was to explore childbirth outcomes in a Swedish population of women reporting a history of violence including domestic

Today, the Internet of Things (IoT) is mainly associated with vertically integrated systems that often are closed and fragmented in their applicability. To build a better IoT ecosystem, the open IoT platform has become a popular term in the recent years. However, this term is usually used in an intuitive way without clarifying the openness aspects of the platforms. The goal of this paper is to cha

The present study investigated the potential moderating role of physical activity on the relationship between parental rejection and poor body image perceptions. Late adolescents and young adults from Turkey (N = 373; 256 females/117 males) reported their memories of upbringing (Egna Minnen Beträffande Uppfostran/EMBU) related to both their mother and father, respectively, levels of physical activ

Circular building design could significantly reduce the environmental impact of buildings and the pressure on natural resources. However, most buildings today are not designed according to the principles of the circular economy. Most literature has focused on either methods for quantifying the lifecycle analysis of buildings and materials, or on innovative circular building materials, but not muchCircular building design could significantly reduce the environmental impact of buildings and the pressure on natural resources. However, most buildings today are not designed according to the principles of the circular economy. Most literature has focused on either methods for quantifying the lifecycle analysis of buildings and materials, or on innovative circular building materials, but not much

The possibility of autonomous artificially intelligent systems (AAIs) has awaken a well-known worry in the scientific community as well as in popular imaginary: the possibility that beings which have gained autonomous intelligence either turn against their creators or at least make the moral and ethical superiority of creators with respect to the created questionable. The present paper argues that

In 2017, the new SMOS-IC retrieval product of soil moisture (SM) and L-band Vegetation Optical depth (L-VOD) was developed. This product relies on a two-parameter inversion of the L-MEB model (L-band Microwave Emission of the Biosphere) which requires little ancillary information and was found to be accurate, making it very well-suited for application in agriculture, hydrology, climate and vegetat

Background: Familial breast cancer risk studies usually overlook the dynamic nature of family history. Methods: The authors assessed the effect of incorporating the timing of cancer diagnosis events into the assessment of familial risks of breast cancer in first-degree and second-degree relatives in a nationwide cohort study of 5,099,172 women (follow-up was between 1958-2015). Family history was

Industrial symbiosis (IS) is a key paradigm for achieving circular economy among industrial firms. Achieving new IS projects often requires outside facilitation, and intermediaries can help solidify and expand existing IS networks. While various intermediary roles have been identified in the literature, less attention has been paid to the potential challenges that intermediaries might encounter in

Peptidoglycan has been retained in chloroplasts that have evolved from cyanobacteria along some evolutionary tracks, but has seemingly been quickly eliminated during evolution of others. It has been eliminated in Rhodophyta, Chlorophyta, Pteridophyta and Spermatophyta, but has been retained in streptophyte algae, Glaukophyta, and Lycophyta. In this article questions emerging from this are raised,

H-infinity optimal control and estimation are addressed for a class of systems governed by partial differential equations with bounded input and output operators. Diffusion equations are an important example in this class. Explicit formulas for the optimal state feedback controller as well as the optimal state estimator are given. Unlike traditional methods for H-infinity synthesis, no iteration i

Background: Dose-dense (DD) adjuvant chemotherapy improves outcomes in early breast cancer (BC). However, there are no phase 3 randomized data to inform on its combination with trastuzumab for patients with human epidermal growth factor receptor 2 (HER2)–positive disease. Methods: This was a protocol-predefined secondary analysis of the randomized phase 3 Pan-European Tailored Chemotherapy (PANTHE