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Widows: agents of change in a climate of water uncertainty

The African continent has been severely affected by the HIV and AIDS pandemic and as a consequence, development is being obstructed. Agriculture and food production systems are changing as a result of the burden of the pandemic. Many farming families are experiencing trauma from morbidity and mortality as well as facing labour losses and exhaustion. To further exacerbate the situation, climate var

"Utopin blir bara bättre ju längre vi väntar på den" - Alexander Kluge och Nachrichten aus der ideologischen Antike

This essay examines the film News from Ideological Antiquity (2008) by German filmmaker Alexander Kluge. Kluge has tried to fulfil the dream of Soviet filmmaker Sergei Eisenstein and make a film version of The Capital by Karl Marx. Kluge’s endeavour is discussed within the context of European left wing cinema, and the film analysis is intertwined with a mapping of the reception of the work in Euro

The role of Smad signaling in hematopoiesis and translational hematology.

Hematopoietic stem cells (HSCs) reside in the bone marrow (BM) of adult individuals and function to produce and regenerate the entire blood and immune system over the course of an individual's lifetime. Historically, HSCs are among the most thoroughly characterized tissue-specific stem cells. Despite this, the regulation of fate options, such as self-renewal and differentiation, has remained elusi

The role of the G protein-coupled receptor GPR30 in the effects of estrogen in ovariectomized mice

Windahl SH, Andersson N, Chagin AS, Martensson UEA, Carlsten H, Olde B, Swanson C, Moverare-Skrtic S, Savendahl L, Lager-quist MK, Leeb-Lundberg LMF, Ohlsson C. The role of the G protein-coupled receptor GPR30 in the effects of estrogen in ovariectomized mice. Am J Physiol Endocrinol Metab 296: E490-E496, 2009. First published December 23, 2008; doi:10.1152/ajpendo.90691.2008.-In vitro studies sug

The role of a simulator-based course in coronary angiography on performance in real life cath lab

Background: The aim of this study was to explore if a course consisting of lectures combined with simulator training in coronary angiography (CA) could accelerate the early learning curve when performing CA on patients. Knowledge in performing CA is included in the curriculum for the general cardiologist. The method, according to American College of Cardiology and European Society of Cardiology gu

Anorectal malformations - their impact on early phases in life

Popular Abstract in Swedish Populärvetenskaplig sammanfattning Född utan ändtarmsöppning – det finns mer hjälp! Varje år föds femtio barn i Sverige utan ändtarmsöppning, så kallad analatresi. De sista 2-3 centimetrarna av ändtarmen saknas liksom ändtarmsöppningen och delar av ringmuskeln. Orsaken tros vara plötsligt uppkomna genförändringar tidigt hos fostret. Starten i livet blir svår eftersom deAbstract: Background : Anorecta l malformation s (ARM) occur in 4: 10000 newborn children with the gender distribut ion 1:1.5 females:males. The reconstruction of ARM, posterior sagiccal anorectal plasty (PSARP), was implemenred worldwide in the late 1980s and therefore the follow-ups are limited. Aims: To assess bowel symptoms in children and adolescents with ARM, operated on with PSARP, and to

Error-correction-based cointegration tests for panel data

This article describes a new Stata command called xtwest, which implements the four error-correction-based panel cointegration tests developed by Westerlund (2007). The tests are general enough to allow for a large degree of heterogeneity, both in the long-run cointegrating relationship and in the short-run dynamics, and dependence within as well as across the cross-sectional units.

Combined ethanol and methane production using steam pretreated sugarcane bagasse

Efficient energy production relies on complementary use of crop residues, to enhance the amount of energy obtained per unit biomass. In this frame, sugarcane bagasse (SB) was pretreated and the resulting slurry and liquid fraction served, respectively, for simultaneous saccharification and fermentation (SSF) at high solid concentration (15%), and anaerobic digestion (AD). More specifically, SB was

The frequency and prognostic impact of dic(9;20)(p13.2;q11.2) in childhood B-cell precursor acute lymphoblastic leukemia: results from the NOPHO ALL-2000 trial

The dic(9;20)(p13.2;q11.2) is reported to be present in similar to 2% of childhood B-cell precursor acute lymphoblastic leukemia (BCP ALL). However, it easily escapes detection by G-banding analysis and its true prevalence is hence unknown. We performed interphase fluorescence in situ hybridization analyses-in a three-step manner-using probes for: (i) CDKN2A at 9p21, (ii) 20p and 20q subtelomeres

A short-lived aeolian event during the Early Holocene in southeastern Norway

The Starmoen dune field is part of a larger aeolian system in the Jomna and Glomma river valleys in southeastern Norway. It is believed to have formed just after the last deglaciation in the area, but no absolute ages have been available to support this. Here, we present a set of quartz optically stimulated luminescence (OSL) ages from the aeolian sediments and the underlying glacifluvial deposits

A NEMO potential that includes the dipole-quadrupole and quadrupole-quadrupole polarizability.

To increase the accuracy of molecular force fields a systematical and balanced improvement of the various terms included is needed. In this work, we have followed this strategy to improve the quality of the NEMO potential for the formaldehyde dimer by introducing local quadrupole moments and higher-order polarizabilities. It is found that inclusion of the quadrupole moment significantly improves t

A beta 40 Oligomers Identified as a Potential Biomarker for the Diagnosis of Alzheimer's Disease

Alzheimer's Disease (AD) is the most prevalent form of dementia worldwide, yet the development of therapeutics has been hampered by the absence of suitable biomarkers to diagnose the disease in its early stages prior to the formation of amyloid plaques and the occurrence of irreversible neuronal damage. Since oligomeric A beta species have been implicated in the pathophysiology of AD, we reasoned

Early changes in myocardial repolarization and coronary perfusion after cardiopulmonary bypass surgery for ASD repair in children

Background: In adults, impaired myocardial repolarization and increased risk of arrhythmia are known consequences of open heart surgery. Little is known, however, about post-operative consequences of cardiopulmonary bypass surgery in children. The aim of this study was to assess ventricular repolarization and coronary perfusion after bypass surgery for atrial septal defect (ASD) repair in children

Inter-domain electron transfer in cellobiose dehydrogenase: modulation by pH and divalent cations

The flavocytochrome cellobiose dehydrogenase (CDH) is secreted by wood-decomposing fungi, and is the only known extracellular enzyme with the characteristics of an electron transfer protein. Its proposed function is reduction of lytic polysaccharide mono-oxygenase for subsequent cellulose depolymerization. Electrons are transferred from FADH(2) in the catalytic flavodehydrogenase domain of CDH to

Neuroinflammation in Lyme neuroborreliosis affects amyloid metabolism

Background: The metabolism of amyloid precursor protein (APP) and beta-amyloid (A beta) is widely studied in Alzheimer's disease, where A beta deposition and plaque development are essential components of the pathogenesis. However, the physiological role of amyloid in the adult nervous system remains largely unknown. We have previously found altered cerebral amyloid metabolism in other neuroinflam