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Manifestation of anharmonic resonance in the interaction of intense ultrashort laser pulses with microstructured targets

Identification of the basic processes responsible for an efficient heating of intense laser produced plasmas is one of the important features of high intensity laser matter interaction studies. Collisionless absorption due to the anharmonicity in the self-consistent electrostatic potential of the plasma, known as anharmonic resonance (AHR), has been proposed to be a basic mechanism but a clear exp

How system quality influences mobile BI use : The mediating role of engagement

Despite the recognized value that mobile BI (m-BI) brings to firms, our understanding of the use of m-BI and its determinants are limited. In this study, we suggest that m-BI system quality characteristics may be among the factors that influence m-BI use. Yet, in the information systems (IS) literature there is mixed support for the relationship between system quality and system use at the individ

Bowel irradiation: the effects on inflammation and matrix-metalloproteinases

Background and aims: Radiotherapy is a valid treatment in cancer multimodal management but it is affected by severe systemic and local side effects. A murine small bowel model was used for the investigation of inflammatory features and apoptosis of local radiotherapy. Similarly the same model was used to analyze the combined effects of radiotherapy and antibiotics in the expression of matrilysin,

Evolution of nucleotide sequences and expression patterns of hydrophobin genes in the ectomycorrhizal fungus Paxillus involutus

Hydrophobins are small, secreted proteins that play important roles in the development of pathogenic and symbiotic fungi. Evolutionary mechanisms generating sequence and expression divergence among members in hydrophobin gene families are largely unknown. Seven hydrophobin (hyd) genes and one hyd pseudogene were isolated from strains of the ectomycorrhizal fungus Paxillus involutus. Sequences wer

Strengthening the case for stimulus-specificity in artificial grammar learning: No evidence for abstract representations with extended exposure

Different theories have been proposed regarding the nature of the mental representations formed as a result of implicit learning of sequential regularities. Some theories postulate abstract surface-independent representations, while other theories postulate stimulus-specific representations. This article reports three experiments investigating the development of abstract representations in artific

Stress sensor triggers conformational response of the integral membrane protein microsomal glutathione transferase 1

Microsomal glutathione (GSH) transferase 1 (MGST1) is a trimeric, integral membrane protein involved in cellular response to chemical or oxidative stress. The cytosolic domain of MGST1 harbors the GSH binding site and a cysteine residue (C49) that acts as a sensor of oxidative and chemical stress. Spatially resolved changes in the kinetics of backbone amide H/D exchange reveal that the binding of

The effect of intestinal ischemia and reperfusion injury on ICAM-1 expression, endothelial barrier function, neutrophil tissue influx, and protease inhibitor levels in rats.

Multiple organ dysfunction syndrome (MODS) is mediated by complex mechanisms in which interactions between activated leukocytes and endothelial cells play a central role. ICAM-1 (intercellular adhesion molecule-1) mediates firm adhesion and transendothelial migration of activated leukocytes from postcapillary venules into the tissue. The present study evaluated the ICAM-1 expression in various org

Machinability of abrasion resistance cast iron with PCBN cutting tools

Highly abrasion and erosive resistance materials are an important group of materials and has very wide applications in many industrial areas. The characteristic properties for this material include the castability and the superior wear resistance. The material, however, is in the group of hard-to-machine materials due to its abrasion to cutting tool and low thermal conductivity. In this article, t

Platelet Factor 4 Impairs the Anticoagulant Activity of Activated Protein C

Platelet factor 4 (PF4) is an abundant platelet alpha-granule chemokine released following platelet activation. PF4 interacts with thrombomodulin and the gamma-carboxyglutamic acid (Gla) domain of protein C, thereby enhancing activated protein C (APC) generation by the thrombin-thrombomodulin complex. However, the protein C Gla domain not only mediates protein C activation in vivo, but also plays

Effects of pentobarbital on GABA-activated currents in acutely-isolated rat dentate gyrus granule neurons

Granule neurons from the rat dentate gyrus were acutely isolated and whole-cell currents recorded. Maximal enhancement of 7 muM gamma-aminobutyric acid (GABA; EC30) evoked currents was obtained with 100 muM pentobarbital where the peak-current was 2.1 +/- 0.2 of control. One hundred muM pentobarbital alone evoked no current response whereas I mM pentobarbital elicited a current response that was 0

Surface complexation and precipitation at the H+-orthophosphate-aged gamma-Al2O3/water interface

Surface complexation of orthophosphate ions at the water-suspended-and-aged gamma-Al2O3/water interface has been studied by means of a series of batch experiments in 0.1 M Na(Cl) medium at 25.0 degrees C in the range 4.8 < -log [H+] < 9.6. The ratio between phosphate concentration and concentration of surface active groups (=AlOH) was varied between 0.15 and 1.50. The suspensions were equilibrated

Bias, Misinformation and the Paradox of Neutrality

What is normally described as bias? A possible definition comprises attempts to distort or mislead to achieve a certain perspective, i.e. subjective descriptions intended to mislead. If designers were able to exclude bias from informing systems, then this would maximize their effectiveness. This implicit conjecture appears to underpin much of the research in our field. However, in our efforts to s

Screening of Mhc variation in Atlantic salmon (Salmo salar): a comparison of restriction fragment length polymorphism (RFLP), denaturing gradient gel electrophoresis (DGGE) and sequencing

We compared three different molecular methods currently used for screening of Mhc variation in population studies of Atlantic salmon. Restriction fragment length polymorphism (RFLP) of the entire class II gene detected 22 haplotypes. Seventeen exon 2 sequences were obtained from individuals carrying the 22 haplotypes, two of which had not been detected by RFLP. The six alleles (27%) detected by RF

Intersubband photoconductivity of self-assembled InAs quantum dots embedded in InP

In this article, we present the results from photoconductivity measurements in the infrared spectral region (3-10 mum) on ensembles of self-assembled InAs quantum dots embedded in a matrix of InP. In the spectral distribution of the photocurrent, peaks are observed which we interpret in terms of transitions from the dots' ground- and first-excited states to the conduction band of the dots/matrix.

The utilization of glycogen accumulating organisms for mixed culture production of polyhydroxyalkanoates.

Production of polyhydroxyalkanoates (PHA) by an open mixed culture enriched in glycogen accumulating organisms (GAOs) under alternating anaerobic-aerobic conditions with acetate as carbon source was investigated. The culture exhibited a stable enrichment performance over the 450 day operating period with regards to phenotypic behavior and microbial community structure. Candidatus Competibacter pho