Individuals identified in the Swedish neonatal alpha1-antitrypsin (AAT) screening study were followed prospectively from their first to their eighteenth year of life. The aim of this study was to analyse the effect of environmental factors, i.e. active and passive smoking, and of clinical factors on lung function and the occurrence of respiratory symptoms in AAT-deficient adolescents. The study gr

A nonlinear dynamic handling model for a tractor-semitrailer combination vehicle is presented in this report. The equations of motion are derived from the fundamental equations of dynamics in Euler's formulation without approximations. The model is modular in the sense that it is easy to change axle configuration, tyre model, suspension model, or to add new features. The primary aim of the model i

Bone strength is determined by bone mineral density (BMD) and bone structure. Dual-energy X-ray absorptiometry (DXA) measures BMD. Whether quantitative ultrasound (qUS) measures a property of bone distinct from BMD is uncertain. To evaluate this, DXA and qUS were measured in 58 fracture patients and 428 controls. To study the independent effects of age and gender on qUS measurements and control fo

To define the early cytogenetic events important in esophageal carcinogenesis, we immortalized normal esophageal epithelial cells by overexpression of human papillomavirus type 16 E6/E7 (HPV16E6/E7) and human telomerase reverse transcriptase (hTERT), and characterized the chromosomal abnormalities serially before and after Cellular immortalizaiton. During crisis. most cells had simple nonclonal ka

Electrochemical properties of two multiforms of laccase from Trametes pubescens basidiomycete (LACI and LAC2) have been studied. The standard redox potentials of the T1 sites of the enzymes were found to be 746 and 738 mV us. NHE for LACI and LAC2, respectively. Bioelectroreduction of oxygen based on direct electron transfer between each of the two forms of Trametes pubescens laccase and spectrogr

A theoretical model is established for diffusion of different types of ions in pore solution of concrete and the coupling to moisture flow and moisture content. Mass exchanges between ions in pore solution and solid hydration products in the concrete are also considered. The basic concepts behind the so-called mixture theory are used.

GABAA receptor alpha 1, beta 3 and gamma 2 subunit mRNA levels have been measured in hippocampus using in situ hybridization, following 1, 10 and 40 seizures produced by rapid kindling stimulations. Major alterations of gene expression were largely confined to the dentate gyrus. One stimulus-induced seizure reduced gamma 2 mRNA levels in the dentate gyrus by 30%. In contrast, mRNA expression incre

Whey protein adsorption on stainless steel surfaces was investigated by in situ ellipsometry under well-defined flow conditions and protein solution residence times. The size distribution in solution of the protein aggregates formed under the same conditions was determined by dynamic light scattering. The adsorption was performed at 72 degrees C and 85 degrees C which is below and above the unfold

OBJECTIVE: Reverse end-diastolic flow is the most pathological type of the umbilical artery flow velocity waveform. We aimed to investigate whether additional prognostic information can be obtained from umbilical artery waveforms in cases with reverse end-diastolic flow. SUBJECTS AND METHODS: Umbilical artery Doppler velocity waveforms from 44 fetuses with reverse end-diastolic flow were analyzed

Objective: To compare the three year safety and efficacy of cyclosporin and parenteral gold in the treatment of early, active, severe rheumatoid arthritis (RA), and to study the reversibility of cyclosporin associated renal dysfunction in patients who discontinued cyclosporin treatment. Methods: The patients continued to receive cyclosporin or parenteral gold in an 18 month open extension to an 18

In this paper an experimental and analytical exploration on the effect of water-binder ratio (w/b), silica fume and age on autogenous, carbonation, drying and total shrinkage of High-Performance Concrete (HPC) is outlined. Eight types of HPC were studied. Carbonation, internal relative humidity (RH) and strength were studied on specimens from the same batch of HPC that was used in the studies of s

We evaluated a Swedish version of a self-administered disease-specific outcome questionnaire for carpal tunnel syndrome regarding reliability, validity and responsiveness to clinical change. It consists of multi-item scales assessing symptom severity, function, patient satisfaction and quality of life. It was given to 102 patients before and 3 months after carpal tunnel release. Test-retest reliab

Popular Abstract in Swedish Kvantdatorer har den unika egenskapen att de kan utföra samma beräkning för många olika startvärden samtidigt. Informationen i en vanlig dator är lagrad i ett minne som består av bitar, som kan ha värdena 1 eller 0. När ett program körs beror slutresultatet av startvärdena hos dessa bitar. Minnet i en kvantdator lagrar istället kvantbitar, som även de kan ha värdena 1 eThe main aim of this work, was to lay the foundations for the experimental realisation of a quantum mechanical controlled NOT gate in rare-earth-metal-ion-doped crystals. Small amounts of rare-earth elements, added during the growth of some inorganic crystals, will become substituted into the crystal lattice as trivalent ions. The trivalent rare-earth-metal ions between cerium, with atomic number

Abstract in French Nous avons étudié une nouvelle technique permettant d’analyser une feuille de papier encochée chargée en mode I, en se basant sur la modélisation cohésive des craquelures. La méthode prévoit la défaillance finale de la feuille, peu importe sa dimension ou la longueur initiale de la craquelure. Le commencement de la craquelure, le développement de la stabilité de la craquelure etA new approach to analyze notched paper sheet loaded in mode I, based on cohesive crack modelling, is investigated. The method predicts final failure of the sheet, regardless of the sheet size and initial crack length. Onset of crack growth, stable crack growth and onset of unstable crack growth are predicted. The simulations of the notched paper sheet reveal that the concept of autonomy, i.e. ind