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Knee arthroplasty: are patients' expectations fulfilled?

Background and purpose With an aging population expecting an active life after retirement, patients' expectations of improvement after surgery are also increasing. We analyzed the relationship between preoperative expectations and postoperative satisfaction and self-reported outcomes with regard to pain and physical function after knee arthroplasty. Patients and methods 102 patients (39 men) with

Equalisation of alcohol participation among socioeconomic groups over time: an analysis based on the total differential approach and longitudinal data from Sweden

Background: Health inequality and its social determinants are well-studied, but the determinants of inequality of alcohol consumption are less well-investigated. Methods: The total differential approach of decomposition of changes in the concentration index of the probability of participation in alcohol consumption was applied to 8-year longitudinal data for Swedish women aged 28-76 in 1988/89. Re

Differently charged polypeptides and their impact on peritoneal and pleural postoperative adhesion formation

Popular Abstract in Swedish Sammanväxningar/ärrbildningar i buken och bröstkorgen efter kirurgiska ingrepp är mycket vanligt. Bland de patienter som opereras kommer cirka 95 % att få någon form av sammanväxningar. Nästan 1 procent av alla inläggningar på kirurgiska avdelningar och tre procent av alla bukoperationer anses i grunden vara orsakade av sammanväxningar i buken. Detta är ett stort antal Organization LUND UNIVERSITY Department of Surgery, Clinical Sciences Skånes University Hospital Lund SE-221 85 Lund Sweden Document name DOCTORAL DISSERTATION Date of issue: November 8, 2013 Author(s): Daniel Åkerberg Sponsoring organization Title and subtitle: Differently charged polypeptides and their impact on peritoneal and pleural postoperative adhesion formation Abstract: Abdominal adhes

OER-Open possibilities for learning. A national initiative financed by the Internet Infrastructure Foundation .SE

Open Educational Resources (OER) are teaching, learning and research materials available on the Internet. Resources are open and free, and usually under creative commons licenses (cc). Depending on the licenses resources are allowed to be used, reused, transmitted, and also sold openly and freely. Internationally, the OER movement is very strong. In Sweden, however, the trend towards open publicat

Estrogen Receptor-{alpha} Phosphorylation at Serine-118 and Tamoxifen Response in Breast Cancer.

Although estrogen receptor-alpha (ERalpha) is a marker used to identify breast cancer patients most likely to benefit from endocrine therapy, approximately 50% of ERalpha-positive breast carcinomas are resistant to tamoxifen. Preclinical studies have shown that phosphorylation of ERalpha at serine-118 (ERalphaS118-P) is required for tamoxifen-mediated inhibition of ERalpha-induced gene expression.

Electron-ion coincidence study of photofragmentation of the CdCl2 molecule

In this work, the photofragmentation subsequent to valence and Cd4d photoionization of cadmium dichloride (CdCl2) were studied using He I and synchrotron excitation. The measurements were performed with a photoelectron-photoion coincidence (PEPICO) setup, and the connection between the singly ionized electronic states and cationic fragments was investigated. The valence-ionized states were found t

Estimation of disruption risk exposure in supply chains

The purpose of the paper is to provide more knowledge on how to estimate disruption risk exposure in the supply chain by developing a conceptual estimation model. The purpose is also to shortly illustrate and discuss by help of a case the possibilities to adapt this theoretical model for use in everyday practice. The developed model, which links disruption risk to disruption source, covers all flo

Sinuosity Effects on Longitudinal Dispersion Coefficient

A method for reaching longitudinal dispersion coefficient accounting sinuosity effects is suggested. The proposed method was verified using 43 sets of measured field data from previous study were collected from 30 streams and these data were chosen depends on characteristics availability (flow parameters, fluid properties and Sinuosity). Statistical programs namely MINITAB and SPSS were used to de

Genetics and Expression of Glycosphingolipids in the P1PK and GLOB Histo-Blood Group Systems

The glycosphingolipid (GSL) antigens in the clinically important P1PK and GLOB blood group systems are present on erythrocytes as well as other tissues and are so-called histo-blood group antigens. Blood group antigens of carbohydrate nature are products of enzymes, so-called glycosyltransferases, adding sugars in a step-wise manner to an acceptor substrate. Presence or absence of the P1PK and GLO

Characterization of MHC class I and II genes in a subantarctic seabird, the blue petrel, Halobaena caerulea (Procellariiformes)

The great polymorphism observed in the major histocompatibility complex (MHC) genes is thought to be maintained by pathogen-mediated selection possibly combined with MHC-disassortative mating, guided by MHC-determined olfactory cues. Here, we partly characterize the MHC class I and II B of the blue petrel, Halobaena caerulea (Procellariiformes), a bird with significant olfactory abilities that liv

Impact of malignant stem cell burden on therapy outcome in newly diagnosed chronic myeloid leukemia patients

Chronic myeloid leukemia (CML) stem cells appear resistant to tyrosine kinase inhibitors (TKIs) in vitro, but their impact and drug sensitivity in vivo has not been systematically assessed. We prospectively analyzed the proportion of Philadelphia chromosome-positive leukemic stem cells (LSCs, Ph+CD34+CD38=) and progenitor cells (LPCs, Ph+CD34+CD38+) from 46 newly diagnosed CML patients both at the

Mild hypothermia markedly reduces ischemia related coronary t-PA release.

In experimentally induced myocardial ischemia, mild hypothermia (33-35 degrees C) has a robust cardioprotective effect. Tissue plasminogen activator (t-PA) is a profibrinolytic enzyme that is released from the vascular endothelial cells in response to ischemia and other injurious stimuli. t-PA has also been found to have proinflammatory properties that could contribute to reperfusion injury. We po

Enhanced flight performance by genetic manipulation of wing shape in Drosophila.

Insect wing shapes are remarkably diverse and the combination of shape and kinematics determines both aerial capabilities and power requirements. However, the contribution of any specific morphological feature to performance is not known. Using targeted RNA interference to modify wing shape far beyond the natural variation found within the population of a single species, we show a direct effect on