Popular Abstract in Swedish Det traditionella jordbruket i nordvästra Europa har gynnat förekomsten av många arter under tusentals år och den snabba övergången till modernt jord- och skogsbruk har lett till försämrade förutsättningar för dessa arter. Både internationellt och nationellt finns strategier för att bevara biologisk mångfald. I Sverige är dessa strategier integrerade i miljömål med ansThis thesis explores the relationship between land-use and floristic diversity over the last three millennia in the uplands of southern Sweden. A quantitative approach based on high-resolution pollen data was applied, using the Landscape Reconstruction Algorithm (LRA), historical maps/aerial photographs, palynological richness and new ways to estimate past evenness at regional and local spatial sc

A single bi-functional monomer, N,O-bismethacryloyl ethanolamine (NOBE), was used in precipitation polymerization system to synthesize molecularly imprinted polymer (MIP) microspheres. Highly specific binding sites were obtained for N-terminal protected neuropeptides, Boc-Leu-enkephalin and Pyr-Leu-enkephalin. The use of NOBE allowed binding sites to be formed in polymer microspheres that are able

Waist-hip ratio (WHR) is a measure of body fat distribution and a predictor of metabolic consequences independent of overall adiposity. WHR is heritable, but few genetic variants influencing this trait have been identified. We conducted a meta-analysis of 32 genome-wide association studies for WHR adjusted for body mass index (comprising up to 77,167 participants), following up 16 loci in an addit

The simulation software for the ATLAS Experiment at the Large Hadron Collider is being used for large-scale production of events on the LHC Computing Grid. This simulation requires many components, from the generators that simulate particle collisions, through packages simulating the response of the various detectors and triggers. All of these components come together under the ATLAS simulation in

The aim of this work was to investigate sorting mechanisms of von Willebrand factor (VWF) when expressed in haematopoietic cells. The processing and sorting of both the wild-type VWF and a multimerization defective propeptide-mutant (VWFm) were investigated after expression in the 32D cell line. Normal proteolytic processing was observed for both proteins, however the processing of VWFm was much s

OBJECTIVE: To determine the impact of improved glycemic control on the development and progression of retinopathy after the institution of insulin therapy in patients with type 2 diabetes and to assess the relation to IGF-1 and hemostatic variables. RESEARCH DESIGN AND METHODS: In a prospective observational study, 45 type 2 diabetic patients were examined at baseline and 1, 3, 6, 12, and 24 month

An algal-bacterial consortium formed by Chlorella sorokiniana and a phenanthrene-degrading Pseudomonas migulae strain was able to biodegrade 200-500 mg/l of phenanthrene dissolved in silicone oil or tetradecane under photosynthetic conditions and without any external supply of oxygen. Phenanthrene was only removed when provided in organic solvent, which confirms the potential of two-phase systems

This study explores boundary-crossing networks in fuel-cell science and technology. We use the case of Norwegian fuel cell and related hydrogen research to explore techno-science networks. Standard bibliometric and patent indicators are presented. Then we explore different types of network maps-maps based on co-authorship, co-patenting and co-activity data. Different network configurations occur f

The objective of the present experiments was to study mechanisms governing cerebrovascular responses during severe hypoglycemia, and in the posthypoglycemic recovery period. To that end, lightly anesthetized (70% N2O) and artificially ventilated rats were injected with insulin so as to abolish spontaneous EEG activity for 15 or 30 min ("coma"). In separate animals, recovery was induced by glucose

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The epitaxial system Sm/Co(0001) was studied for Sm coverages up to 1 monolayer (ML) on top of ultrathin Co/W(110) epitaxial films. Two ordered phases were found for 1/3 and 1 ML Sm, respectively. The valence state of Sm was determined by means of photoemission and magnetic properties were measured by magneto-optical Kerr effect. We find that 1 ML Sm causes a strong increase of the coercivity with

Studies of haematological neoplasms have shown that alterations in structure and/or expression of transcription factor genes may play a crucial role for transforming stem cells or progenitor cells into malignant cells. These mutations typically arise through balanced translocations and appear to induce a block in cellular differentiation. The impact of the transforming mutation is highly dependent

The dystrophin-glycoprotein complex (DGC) is a multisubunit complex that connects the cytoskeleton of a muscle fiber to its surrounding extracellular matrix. Mutations in the DGC disrupt the complex and lead to muscular dystrophy. There are a few naturally occurring animal models of DGC-associated muscular dystrophy (e.g. the dystrophin-deficient mdx mouse, dystrophic golden retriever dog, HFMD ca

The aim of this study was to evaluate the global sequence of repolarization over the ventricular endocardium. Disturbances in myocardial repolarization are associated with the genesis of arrhythmias. However, little is known about the global sequence of repolarization. Monophasic action potentials (MAPs) were recorded from 61 +/- 18 LV and/or RV sites in ten healthy pigs and from 43 +/- 15 LV or R

In an investigation by the Swedish Cancer Society, an expert group described the present status, critical issues and future aspects and potentials for each of nine major areas of radiation therapy research. The present report deals with the use of sensitizing and protective substances in radiation therapy and predictive assays on normal tissues and tumour response.

This report deals with stability and validity analyses of direct tension tests, and an investigation into structural behaviour of various materials in tensile fracture. The influence of rotation in damage zone on the stress-deformation curve is investigated. The role of rotation stiffness of testing set-ups for a stable tension test is analysed. The bump effect, i.e. steep stress drops in stress-d