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OBJECTIVE: Sex steroids exert important biological functions within the central nervous system (CNS), but the underlying mechanisms are poorly understood. The contribution of circulating sex steroids to the levels in CNS tissue and cerebrospinal fluid (CSF) has been sparsely investigated in human and with inconclusive results. This could partly be due to lack of sensitive validated assays. To addr

High-order harmonic generation (HHG) is an ubiquitous tool of great interest in many fields of research from imaging to ultrafast spectroscopy [1]. In its most common implementation, an intense (≈ 1014 W/cm2) infrared (IR) pulse is focused on a noble gas target yielding a train of attosecond pulses in the extreme ultraviolet (XUV) spectral region. By adopting proper strategies and target geometrie

Background/aim: Enterococcus faecalis and Enterococcus faecium cause human infections including bacteraemia and infective endocarditis (IE). Only few studies describing non-faecalis and non-faecium Enterococcus (NFE) infections have been conducted. We aimed to describe the incidence, prognosis, and focus of infection of bacteraemia with NFE. Methods: This retrospective population-based study inclu

Combining highly efficient nanophotonic structures into artificial neural networks hold significant promise for superior hardware solutions [1]. Well-defined circuit architectures and concepts, with limited size and clear functionality are useful to develop and verify such novel concepts. Insects are capable of amazing autonomous feats well beyond current computers, such as navigating across hundr

The 2023 Yearbook of Socio-Economic Constitutions, dedicated to ‘Law and the Governance of Artificial Intelligence’, explores the timely and complex issues surrounding the emergence of artificial intelligence (AI) technologies. The volume delves into the transformative potential of AI in various sectors such as law enforcement, healthcare, and recruitment, while also highlighting the growing globa

The aim of the present study was to assess the psychometric properties of a Swedish translation of the Sexual Orientation Microaggressions Scale (SOMS) in a convenience sample of 267 Swedish LGB+ people (Mean age = 36.41). Testing suggested some strengths in terms of factor structure and 2-week test-retest reliability (ICC > .79). Also, internal consistency (α = .80–.91) and convergent validity we

Background: Transcatheter aortic valve implantation (TAVI) has become a safe procedure. However, complications occur, including uncommon complications such as valve malposition, which requires the implantation of an additional rescue valve (rescue-AV). The aim was to study the occurrence and outcomes of rescue-AV in a nationwide registry. Methods: The Swedish national TAVI registry was used as the

Expectations and demands on coproduction in research have increased. Therefore, there is a need for knowledge on how these coproducing processes where researchers and practitioners work side by side during the research process can be carried out. In this article, methodological questions related to coproduction and collaboration between researchers and practitioners in the field of social work are

DEBATE. We researchers have long demanded that the government take climate research seriously and speed up the transition to a sustainable society.Instead, the government is pursuing a policy that deliberately increases emissions. Now more citizens need to raise their voices and show that we demand a knowledge-based climate transition, and it is urgent.

The digital transformation is rapidly changing in-store service settings. This paper explores how frontline employees experience and cope with technology-related challenges. Based on a qualitative approach and the use of observations and interviews, this research advances our understanding of how such coping is performed in retail stores and how it contributes to defining employees’ work experienc

Förebyggande av oönskade graviditeter och sexuellt överförbara infektioner (vad jag kallar "contracepting") behandlas ofta som ett medicinskt eller hälsovårds- problem snarare än en social fråga. Till följd av detta, förblir mycket av det vardagliga arbetet som preventivmetoder innefattar osynligt. Unga människor i synnerlighet talas oftare om än med när det kommer till deras användning av preventContraception is a complex phenomenon with differing meanings, expressions, and materialities depending on its historical, social, and cultural context. In this thesis, I depart from the conceptualisation of contraception as the prevention of both pregnancies and sexually transmitted infections (STIs) and I name these practices through the collective term of contracepting. Previous research on you

Empowering Children and Youththrough Law and ParticipationIn 2023, between August the 30th and September the 1st, the Child RightsInstitute at the Department of Sociology of Law, within Faculty of SocialSciences, Lund University, was arranging a three-day research conference onthe theme Empowering Children and Youth through Law and Participation.41 participants from 13 different countries particip

Introduction: Systemic lupus erythematosus (SLE) is an autoimmune connective tissue disease affecting multiple organs in the human body, including the central nervous system. Recently, an artificial intelligence method called BrainAGE (Brain Age Gap Estimation), defined as predicted age minus chronological age, has been developed to measure the deviation of brain aging from a healthy population us

Classifying active galactic nuclei (AGNs) is a challenge, especially for BL Lacertae objects (BLLs), which are identified by their weak emission line spectra. To address the problem of classification, we use data from the fourth Fermi Catalog, Data Release 3. Missing data hinder the use of machine learning to classify AGNs. A previous paper found that Multivariate Imputation by Chain Equations (MI

The upper layer of our skin, the stratum corneum (SC), is a versatile material that combines mechanical strength with efficient barrier function. In this paper, we discuss these macroscopic properties of SC in relation to recent findings on molecular responses and structural diversity in SC protein and lipids. We put particular focus on the intermediate (colloidal) length scale and how the differe

The ECG diagnosis of LVH is predominantly based on the QRS voltage criteria, i.e. the increased QRS complex amplitude in defined leads. The classical ECG diagnostic paradigm postulates that the increased left ventricular mass generates a stronger electrical field, increasing the leftward and posterior QRS forces. These increased forces are reflected in the augmented QRS amplitude in the correspond

BACKGROUND: Small-cell lung cancer (SCLC) molecular subtypes have been primarily characterized based on the expression pattern of the following key transcription regulators: ASCL1 (SCLC-A), NEUROD1 (SCLC-N), POU2F3 (SCLC-P) and YAP1 (SCLC-Y). Here, we investigated the proteomic landscape of these molecular subsets with the aim to identify novel subtype-specific proteins of diagnostic and therapeut

BACKGROUND: Patients with kidney failure have a high risk for cardiovascular events. We aimed to evaluate the prognostic importance of selected biomarkers related to haemostasis, endothelial function, and vascular regulation in patients with acute coronary syndrome (ACS), and to study whether this association differed in patients with renal dysfunction.METHODS: Plasma was collected in 1370 ACS pat