Sökresultat

Reglering och transport av S100A9 i cancer S100A9 är ett protein involverat i immunförsvaret och fungerar som en signal mellan olika celler för att optimera inflammation. Bortsett från det, har immunförsvaret som roll att bekämpa cancer. Där blir i stället effekten av S100A9-signalering att immunförsvarets attack dämpas och tumören gynnas. Det är därför av intresse att veta mer om detta signalsysS100A9 is a calcium binding protein commonly found in cancer, autoimmunity and inflammation. Factors in the tumor microenvironment can induce cancer cells to start expressing S100A9. This protein has also been found to be up regulated and have different subcellular distribution during hypoxia. In this study I used western blot to analyze the regulation of expression and intra-cellular transport of

Mammalian cells are frequently under stress leading to DNA damage because of UV exposure, ionizing radiation or genotoxic chemicals. Cells have evolved a DNA damage response (DDR) mechanism to ensure survival and pass on the correct genetic information to the next generation. MITF is a melanocyte-specific transcription factor. It has been shown to accumulate in the vicinity of DNA damage and its e

A mysterious gene found in many bacteria Recently, a gene called ctaM was discovered in Staphylococcus aureus, a common cause of skin infections etc., required for the bacterium to respire efficiently. It was demonstrated that the protein encoded by this gene is essential for the function of cytochrome aa3, that catalyzes the reduction of O2 to form H2O in respiration. A gene encoding a similar p

The single-stranded telomere ends The telomeres are tandem repeat DNA sequences at the ends of our chromosomes. They are very important for the protection of our genomic DNA, and keeps it from being degraded and helps it staying intact. Genomic DNA is usually double-stranded, but on the very ends of the telomeres we find single-stranded ends which are called the 3’overhangs. These overhangs are

This study investigates the effect of unemployment on health and rank-dependent indices of income-related health inequality in Europe during the period 2006-2015, using data from the Survey of Health, Ageing and Retirement in Europe. I use a recently proposed general method of decomposition and a panel data approach with individual fixed effects, and find a significant negative relationship betwee

Entrepreneurial motivations are still a relatively undiscovered research field (Carsrud & Brännback, 2010). More specifically there seems to be a gap in the literature about the motivation of older entrepreneurs (Weber & Schaper, 2004). Weber and Schaper (2004) mentioned that this segment will have a growing impact upon national economic performance, policy frameworks, academia and the bus

Igenkänning och signalering av växthormonet brassinosteroid i korn Under svåra väderförhållanden som starka vindar, hagel eller hårt regn kan grödor som korn pressas mot marken – man får liggsäd. Dessa löper större risk att drabbas av svampinfektioner, de börjar gro och de blir svårare att tröska vilket minskar skörden. Sädesslag som korn, vete och råg är extra utsatta, vilket skapar ett behov av

This study aims to explore how the Swedish Migration Court’s decision is legitimized or delegitimized in discourses in civil society, outside the legislative and judicial power. This is explored with a case study on a judicial decision to expel Sonya, a 90-year-old and sick Ukrainian woman. The material is collected from social media platforms where this case has been discussed. Thus, the results

The study focuses on the impact of United Kingdom’s vote for leaving the European Union on the banks stocks in Europe. The tool used for measuring this impact is event study. Putting the center of attention on the banking industry, we investigate 63 major banks in Europe. Abnormal returns are defined by using the well-known market model. As expected, the results show that banks experience signific

Vems sida står du på? Hur har utvecklingen av miljökommunikation i praktiken ändrats under de senaste 30 åren? Denna studie utför en semiotisk textanalys på fyra visuella texter som är publicerade av organisationen WWF. Den identifierar och analyserar de tecken och koder som används i visuell marknadsföring för att kommunicera strategiska budskap till mottagaren. Vidare analyseras hur WWF använder

The aim of this study was to investigate whether social media influence young adults’ food choices through social modelling. Before the main study, a pilot was conducted to improve and develop scales for measuring the influence of social modelling, as well as some control variables. In the main study, 354 young adult participants (ages 18-35) were recruited through social media and completed an on

This study is concerned with the topic of sentence-final intonation in wh-questions, yes/no- questions and declaratives. The aim of the study is to investigate whether native speakers of Swedish can recognize these sentence types in standard Japanese by listening to the intonation alone. In addition, whether exposure to the language affects the ability to distinguish these sentence types is invest

This paper studies the implementation of capital controls in Greece and examines their impact on consumption and imports. The dataset consists of the quarterly country-level macroeconomic variables, per capita final consumption expenditure of households, per capita imports of goods and services and per capita exports of goods and services, of 10 countries for the period 2010-2016. The method appli

I en undersökning av gällande svensk rätt och praxis har det immaterialrättsliga skyddet för videospel i förhållande till upphovs- och patenträtt undersökts. Videospel åtnjuter ett immaterialrättsligt skydd i Sverige som i stora drag är täckande. Inom upphovsrätten har videospel länge skyddats som datorprogram. Samma specialbestämmelser som gäller för datorprogram har då gället för videospel. SkydIn an examination of current Swedish law and practice, has the intellectual property protection for video games in relation to copyright and patent law been investigated. The protection of the intellectual rights for video games in Sweden are comprehensive. In copyright law video games have long been protected as a computer program. All the regulation which have been applicable to programs have al

The Church of Sweden is marginalized in society and the membership of the Church is decreasing, which means that the church's economy is on the decline, but the demands on the Church by its members have not decreased. This is a comparative study that deals with the roles of deacons and priests and their contribution to the Church. The aim is to get an overview of similarities and differences i

Uppsatsen syftar till att med en bred ansats, innefattandes av juridiska, moraliska och mänskliga rättigheter dilemman förklara inträdet av den brittiska asyllagen under 2000-talet. Under tiden som NATO hade militär aktivitet i Afghanistan (under ledning av International Assistance Security Force), däribland Storbritannien (från 2001 fram till och med 2014) hade dem anställt cirka hundratals afghaThe paper engages a provocative, multi-dimensional legal, moral and human rights issue that strikes at the heart of 21st century UK asylum law. Throughout the NATO Afghanistan military campaigns (headed by the International Security Assistance Force) in which the UK committed combat troops from 2001 to 2014, hundreds of local Afghan nationals were employed by the British Army as interpreters and t

The purpose of this project was to develop a better understanding of the re- sponse of a pixelated thermal-neutron detector, which will be used as a thermal- neutron detector at one of the beam lines at the European Spallation Source in Lund, Sweden. The detector consists of a thin Lithium6-glass scintillator, a multi-anode photomultiplier tube and associated read-out electronics. Initial characte

The thesis examines the marketing strategies implemented by the two biggest e-commerce companies in Japan, namely Rakuten and Amazon.co.jp, in order to address their international customers. Specifically, the study is conducted by means of a multiple-case study design, an interpretivist approach and a qualitative Web Content Analysis on the two firms’ websites in English language. The theoretical

In this work we carry out a thorough analysis of applying a specific field within machine learning called generative adversarial networks, to the art of natural language generation; more specifically we generate news text articles in an automated fashion. To do this, we experimented with a few different architectures and representations of text, evaluated the results and used the information retri