We recently established a skin organ culture model for epithelial healing by creating a central defect in freshly excised human skin specimens and keeping them in culture for up to 7 days, either untreated or with transplantation of allogenic or autologous keratinocytes. In this study the molecular diversity of cell-cell junction proteins in the regenerating epidermis was analysed immunohistochemi

The role of the exocrine pancreas in regulating gut microflora colonization is unclear. The main objective in the present study was to assess the affect of pancreatic fluid on the growth of pathogenic bacteria and fungi. Pancreatic juice samples used in the study were obtained from nine eight-week old weaned pigs in which catheters were implanted in the pancreatic duct. The antibacterial activity

Type 2 diabetes (T2D) is a complex, metabolic disorder characterized by hyperglycaemia because of defects in insulin secretion and sensitivity. The rapid increase in T2D is likely to reflect the influence of both genetic and environmental factors in disease development. However, the genetic aetiology of T2D remains largely unknown. Thus, the aim of this thesis was to study the role of genetic vari

PURPOSE: To determine the effective time window for MR imaging of tumors with blood-brain barrier (BBB) damage after injection of Gd-containing contrast media. MATERIAL AND METHODS: Eleven patients with 15 brain lesions (metastasis, glioma, abscess) were studied with a T1-weighted spin-echo sequence repeated over periods of up to 43 min after contrast injection. A quotient was calculated between t

An extensive follow-up study of day- and night-active Macrolepidoptera was performed during 2004 at the Kullaberg Nature Reserve located in the south-western part of Sweden. Butterflies were surveyed in an area of 100 km(2) and night-active moths were trapped in the core area of the reserve. Macrolepidopteran species resident in the area in the 1950s were compared with species resident in the area

Analys av Greta Garbo som filmstjärna och kulturfenomen

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BACKGROUND: We have investigated the association between Helicobacter pylori and gastric carcinoma through a nested case-control study in a single city. METHODS: From a cohort of 32,906 residents recruited from 1974 through 1992, 56 cases of gastric adenocarcinoma and 224 matched controls were selected. The mean interval between serum collection and diagnosis was 5.7 years. Frozen serum or plasma

This document is a description of the computer code OSFIC. The development of the code was sponsored by the Swedish Nuclear Power Inspectorate as an effort to develop useful tools for fire analyses in nuclear power plants. The name OSFIC stands for "OilSpill Fires In Compartments". The purpose of this paper is to describe the code and to facilitate the use of the computer program. A more detailed

The self-assembly behavior of a cationic surfactant (dodecyltrimethylammonium) with DNA as counterion in mixtures of water and decanol was investigated. The phase diagram was established and the different regions of the phase diagram characterized with respect to microstructure by H-2 NMR (D2O), small-angle X-ray scattering (SAXS), and other techniques. The DNA-cationic surfactant aggregate is vir

Based on data available at the IAU (International Astronomical Union) Meteor Data Center in Lund 60 precisely reduced photographic Orionid orbits and 17 video observed orbits are analysed. Mean photographic and video orbits are compared with the orbit of comet Halley. The Orionid meteoroid stream structure and radiant motion is studied, and compared with previous visual and photographic studies of

Scientific knowledge develops in an increasingly fragmentary way. A multitude of scientific disciplines branch out. Curiosity for this development leads into quests for a unifying understanding. To a certain extent, foundational studies provide such unification. There is a tendency, however, also of a fragmentary growth of foundational studies, like in a multitude of disciplinary foundations. We s

Popular Abstract in Swedish I Sverige inträffar varje år c:a 1 500 självmord och minst 15 000 självmordsförsök. Självmordsbeteende är således ett problem som berör många människor i vårt samhälle. En grupp som löper en klart förhöjd risk att begå självmord är de personer som gjort självmordsförsök. "Självmordsförsökare" utgör dock en heterogen grupp av människor av olika ålder, kön, sociala omstänBetter understanding of suicidality may improve treatment and care of suicide attempters. This thesis aims at understanding suicidality by investigating suicide risk, sex differences and views of suicide attempters. Suicide risk factors (prospectively determined) differed between the sexes: Older age and high suicidal intent were female risk factors, whereas previous attempts and using a violent

There is a general lack of rapid, sensitive, and quantitative methods for the detection of differentiating human embryonic stem cells (hESCs). Using light microscopy and immunohistochemistry, we observed that morphological changes of differentiating hESCs precede any major alterations in the expression of several commonly used hESC markers (SSEA-3, SSEA-4, TRA-1-60, TRA-1-81, Oct-4, and Nanog). In