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Pathogenic T-cell responses in patients with autoimmune thrombocytopenic purpura

Autoimmune thrombocytopenic purpura (AITP) is a bleeding disorder in which autoantibodies are directed against an individual's own platelets, leading to enhanced clearance through Fc receptor (R)-mediated phagocytosis by macrophages residing in the reticuloendothelial system, particularly in the spleen. This review surveys the recent current literature and updates our understanding of the cell-med

Weapons of Brand Destruction: Exploring the different methods and strategies used by Online Anti-Brand Communities aimed to harm brands

Aim: The aim of this paper was to shed light on the different methods/strategies that Anti-Brand Communities (ABCs) use in order to cause harm to particular brands. Purpose: The purpose of this paper is to offer assistance to brand managers through Anti-Brand Community-insights, as a means of combating the increasingly growing number of ABCs. Research Question: What methods/strategies do anti-b

The Swedish way: Turning down a common currency and its effects on economic development

This thesis aims at evaluating the Swedish decision not to adopt the euro even though this is thought to bear economic benefits. In particular, my research confronts the question: What would have been Sweden’s economic development if the country would have adopted the euro in 1999? By taking advantage of the synthetic control method, I scrutinize the potential developments of both, Sweden’s bilate

DNA movement in sub-20 nm nanoslits

The movement of XbaI digested O-DNA in 20 nanometer and O-DNA in 12 nanometer high slits was investigated. We found that DNA moved intermittently and following preferential pathways, indicating an important influence of surface roughness. From these intermittent movements two different mobilities were calculated, the total averaged mobilities and averaged mobilities between the intermittent sticki

Correction of magnetization transfer saturation maps optimized for 7T postmortem MRI of the brain

PurposeMagnetization transfer saturation (MTsat) is a useful marker to probe tissue macromolecular content and myelination in the brain. The increased B1+ inhomogeneity at 7T and significantly larger saturation pulse flip angles which are often used for postmortem studies exceed the limits where previous B1+correction methods are applicable. Here, we develop a calibration-based correction model an

What besets entrepreneurs in renewable energy sector? – Insights from the Indian state of Gujarat

Purpose: India has acquired global leadership in renewable energy (RE) deployment because of its commitment to achieve 175 GW of installed capacity by 2022. Entrepreneurship driven by innovation and policy push is essential for energy sector transition. Despite policy focus on the diffusion of RE technology, there are several challenges that plague innovation and RE entrepreneurship development in

Could Experimental Inflammation Provide Better Understanding of Migraines?

Migraines constitute a common neurological and headache disorder affecting around 15% of the world’s population. In addition to other mechanisms, neurogenic neuroinflammation has been proposed to play a part in migraine chronification, which includes peripheral and central sensitization. There is therefore considerable evidence suggesting that inflammation in the intracranial meninges could be a k

Airborne Wear Particles from Dry Clutches

A significant part of non-exhaust particle emissions in cities comes from the wear of vehicle components. Several studies on airborne particles from the wear of disc brakes and tires have been completed. However, few publications can be found in the scientific literature regarding airborne emissions from dry clutches used in road vehicles. With this in mind, this preliminary study designs a clutch

Kollektivavtal: Så ser de vita fläckarna ut

I Sverige omfattas 9 av 10 anställda av kollektivavtal. Täckningsgraden är hög, men det finns vissa branscher och typer av företag där förekomsten av kollektivavtal, av olika anledningar, är låg. Professor Anders Kjellberg vid Lunds universitet redogör för hur den svenska kollektivavtalskartan ser ut.

The value of novel biomarkers for prediction of vascular disease during long term follow-up

Introduction: Plasma biomarkers may be useful to detect healthy individuals at increased risk for development of peripheral arterial disease (PAD), carotid artery stenosis (CAS), or abdominal aortic aneurysm (AAA). The subset of plasma biomarkers studied regarding associations with incident cardiovascular disease during long-term follow-up in this thesis were the inflammatory markers lipoprotein -Introduction: Plasma biomarkers may be useful to detect healthy individuals at increased risk for development of peripheral arterial disease (PAD), carotid artery stenosis (CAS), or abdominal aortic aneurysm (AAA). The subset of plasma biomarkers studied regarding associations with incident cardiovascular disease during long-term follow-up in this thesis were the inflammatory markers lipoprotein -

SEPARATION OF CLUSTERS OF GROUP A STREPTOCOCCI USING DETERMINISTIC LATERAL DISPLACEMENT

Differences in morphologies of bacteria and bacteria clusters are known to influence their pathogenicity. However, it is difficult to separate cells and cell clusters based on morphology using standard cell biological methods, making studies of the underlying mechanisms difficult. Here we report a simple label-free method for the continuous separation of clusters of group A streptococci, based on

Counterfeit products affect on brand equity: A case study on how counterfeit products affect a luxury brand’s brand equity

Purpose: The purpose of this paper is to investigate how counterfeit products affect a brand’s brand equity with the help from a consumer perspective. Research question: What is the consumer’s perception of counterfeit products? How and why does the consumer’s perception of counterfeit products affect a brand’s brand equity? Methodology: This research paper was based on quantitative research,