Ollier disease and Maffucci syndrome are non-hereditary skeletal disorders characterized by multiple enchondromas (Ollier disease) combined with spindle cell hemangiomas (Maffucci syndrome). We report somatic heterozygous mutations in IDH1 (c.394C>T encoding an R132C substitution and c.395G>A encoding an R132H substitution) or IDH2 (c.516G>C encoding R172S) in 87% of enchondromas (benign cartilage

Objective: This study aimed to evaluate the outcome and predisposing factors related to perioperative bleeding in patients treated with endovascular aneurysm repair (VAR) for ruptured and non-ruptured abdominal aortic aneurysm (AAA). Design: This was a retrospective cohort study. Methods: A total of 525 consecutive patients (73% elective) with AAA underwent EVAR at two vascular centres from 2008 t

The aim of this study was to translate and adapt the Sydney Swallow Questionnaire to Swedish conditions and to evaluate the validity and test-retest reliability of the Swedish translation in patients with oropharyngeal dysphagia and in healthy controls.

Two species of the genus Choricystis (Choricystis minor and Choricystis chodatii) have been chromosomally surveyed. In addition, their ability to form symbiotic associations with the ciliate Paramecium bursaria was also investigated. Choricystis minor (clone #8931/1 from strain #8931) was isolated from a moss sample collected on Livingston Island, Maritime Antarctica. Choricystis chodatii (clone #

The neurocognitive outcome of children born with extremely low birth weight (ELBW) is highly variable due to the complexity of morbidity. So far, no study has compared comprehensive neuropsychological test profiles in groups with different neuromotor status. In a national cohort of ELBW children neuropsychological test profiles were assessed in 4 groups defined according to a neurological examinat

The gamma p -> K-0 Sigma(+) reaction has been measured from threshold to E-gamma = 1.45 GeV (W-CM = 1.9 GeV) using the Crystal Ball and TAPS multiphoton spectrometers together with the photon tagging facility at the Mainz Microtron MAMI. In the present experiment, this reaction was searched for in the 3 pi(0)p final state, by assuming K-S(0) -> pi(0)pi(0) and Sigma(+) -> pi(0)p. The experimental r

We performed a genome-wide association study on 1,292 individuals with abdominal aortic aneurysms (AAAs) and 30,503 controls from Iceland and The Netherlands, with a follow-up of top markers in up to 3,267 individuals with AAAs and 7,451 controls. The A allele of rs7025486 on 9q33 was found to associate with AAA, with an odds ratio (OR) of 1.21 and P = 4.6 x 10(-10). In tests for association with

We verified an active uptake of kleptoplastids in the toxic and bloom-forming dinoflagellates of the genus Dinophysis from its preferred prey, the ciliate Myrionecta rubra, using a quantitative real-time PCR technique. During a 65 d starvation/feeding experiment with Dinophysis caudata, changes in plastid 16S rRNA, plastid autofluorescence and plastid/nuclear DNA ratio through the cell cycle were

This paper presents measurement results of electricity use and lighting conditions in individual office rooms located in Lund, Sweden. The aim is to demonstrate the energy saving potential by using different lighting systems and the satisfaction of users. The measurements are carried out in one empty reference room and four fully occupied test rooms equipped with different electric light control s

In this paper we introduce two new methods for constructing harmonic morphisms from solvable Lie groups. The first method yields global solutions from any simply connected nilpotent Lie group and from any Riemannian symmetric space of non-compact type and rank r ≥ 3. The second method provides us with global solutions from any Damek–Ricci space and many non-compact Riemannian symmetric spaces. We

Salutogenesis focuses on how come people recover or stay well. The answer was described to be a Sense of Coherence (SOC). SOC is a global orientation which contributes to how flexible coping strategies are chosen. The SOC concept was operationalized in The Sense of Coherence Scale (SOC-29). The questionnaire address to what extent life is perceived as comprehensible, manageable, and meaningful. T

Objectives: To perform a genome-wide association study (GWAS) using the Immunochip array in 3,420 cases of ischemic stroke and 6,821 controls, followed by a meta-analysis with data from more than 14,000 additional ischemic stroke cases. Methods: Using the Immunochip, we genotyped 3,420 ischemic stroke cases and 6,821 controls. After imputation we meta-analyzed the results with imputed GWAS data fr

This paper provides a review of research into financialisation of the environment, focusing on the role of financialisation in the interface between social and natural dimensions of sustainability, the geographical penetration of finance into environmental sectors, and its increasing control over the production of nature and environmental governance through regulating flows of capital and conseque

We have measured the ambipolar diffusion lengths in nanowires with GaAs and AlGaAs core material using cathodoluminescence imaging. This was done by combining III-V semiconductor materials with different bandgaps in single nanowires. We show that it is possible to record intensity profiles of the emission from segments of lower bandgap material positioned along the nanowire length and in this way

Acute myeloid leukemia with t(6; 9)(p22; q34) is listed as a distinct entity in the 2008 World Health Organization classification, but little is known about the clinical implications of t(6; 9)-positive myeloid leukemia in children. This international multicenter study presents the clinical and genetic characteristics of 62 pediatric patients with t(6; 9)/DEKNUP214-rearranged myeloid leukemia; 54

We report on the implementation of a high-count-rate charged particle imaging detector for two-color pump-probe experiments at the free electron laser in Hamburg (FLASH). In doing so, we have developed a procedure for finding the spatial and temporal overlap between the extreme UV free electron laser (FEL) pulses and the IR pulses, which allows for complete alignment of the setup in situations whe

Cardiovascular-MR (CMR) is the gold standard for quantifying myocardial infarction using late gadolinium enhancement (LGE) technique. Both 2D- and 3D-LGE-sequences are used in clinical practise and in clinical and experimental studies for infarct quantification. Therefore the aim of this study was to investigate if image acquisitions with 2D- and 3D-LGE show the same infarct size in patients and e

Aims To compare the British Isles Lupus Assessment Group (BILAG) 2004, the Safety of Estrogens in Lupus Erythematosus National Assessment (SELENA) flare index (SFI) and physician's global assessment (PGA) in assessing flares of disease activity in patients with systemic lupus erythematosus (SLE). Methods Sixteen patients with active SLE were assessed by a panel of 16 rheumatologists. The order in