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Post-saccadic oscillations in eye movement data recorded with pupil-based eye trackers reflect motion of the pupil inside the iris

Abstract in UndeterminedCurrent video eye trackers use information about the pupil center to estimate orientation and movement of the eye. While dual Purkinje eye trackers suffer from lens wobble and scleral search coils may be influenced by contact lens slippage directly after saccades, it is not known whether pupil-based eye trackers produces similar artifacts in the data. We recorded eye moveme

Selective Removal of Photoreceptor Cells In Vivo Using the Biodegradable Elastomer Poly(Glycerol Sebacate)

Retinal transplantation experiments have advanced considerably during recent years, but remaining diseased photoreceptor cells in the host retina physically obstruct the development of graft-host neuronal contacts which are required for vision. We here report selective removal of photoreceptors using the biodegradable elastomer poly(glycerol sebacate) (PGS). A 1x3 mm PGS membrane was implanted in

Turning Vinegar into Wine: Humorous Self-Presentations among Older GLBTQ Online Daters

Abstract in UndeterminedThis study investigates humorous and self-mocking comments about age and age-related appearance among older gay, lesbian, bisexual, transsexual and queer advertisers in two Swedish Internet dating forums. Using a perspective where age is regarded as an accomplishment, humor was investigated as a way of relating to restrictive norms concerning age and sexuality. It was concl

Adsorption of phenanthrene on Al (oxy) hydroxides formed under the influence of tannic acid

Although there has been substantial research done on adsorption of metals/metalloids by Al (oxy)hydroxides, little is known regarding the adsorption of polyaromatic hydrocarbons (PAHs) on Al (oxy)hydroxides, especially those formed in the presence of organic acid. This paper investigated the adsorption of phenanthrene on Al (oxy)hydroxides formed with initial tannate/Al molar ratios (MRs) 0, 0.001

Long-Term Results of a Multicenter Study on Subthalamic and Pallidal Stimulation in Parkinson's Disease

We report the 5 to 6 year follow-up of a multicenter study of bilateral subthalamic nucleus (STN) and globus pallidus internus (GPi) deep brain stimulation (DBS) in advanced Parkinson's disease (PD) patients. Thirty-live STN patients and 16 GPi patienis were assessed at 5 to 6 years after DBS surgery. Primary outcome measure was the stimulation effect on the motor Unified Parkinson's Disease Ratin

Peak Metals, Minerals, Energy, Wealth, Food and Population: Urgent Policy Considerations for a Sustainable Society

Several strategic metals, elements and energy resources are about to run into scarcity in the near future under the present paradigm of use. A global systems model has been developed (WORLD) to assess the issue of scarcity and its implications for society. We show that scarcity may lead to “peak wealth”, “peak population”, “peak waste” and “peak civilization”, unless urgent counter-measures are sy

A Random Coefficient Approach to the Predictability of Stock Returns in Panels

Most studies of the predictability of returns are based on time series data, and whenever panel data are used, the testing is almost always conducted in an unrestricted unitby- unit fashion, which makes for a very heavy parametrization of the model. On the other hand, the few panel tests that exist are too restrictive in the sense that they are based on homogeneity assumptions that might not be tr

Search for Pair Production of a Heavy Up-Type Quark Decaying to a W Boson and a b Quark in the lepton plus jets Channel with the ATLAS Detector

A search is presented for production of a heavy up-type quark (t') together with its antiparticle, assuming subsequent decay to a W boson and a b quark, t'(t) over bar' -> W(+)bW(-)(b) over bar. The search is based on 1.04 fb(-1) of proton-proton collisions at root s = 7 TeV collected by the ATLAS detector at the CERN Large Hadron Collider. Data are analyzed in the lepton + jets final state, chara

Nuclear Modification of psi ', chi(c), and J/psi Production in d plus Au Collisions at root s(NN)=200 GeV

We present results for three charmonia states (psi' chi(c), and J/ psi) in d + Au collisions at vertical bar y vertical bar < 0.35 and root s(NN) = 200 GeV. We find that the modification of the psi' yield relative to that of the J/ psi scales approximately with charged particle multiplicity at midrapidity across p + A, d + Au, and A + A results from the Super Proton Synchrotron and the Relativisti

The tyrosine kinase CSK associates with FLT3 and c-Kit receptors and regulates downstream signaling.

Type III receptor tyrosine kinases (RTKs), FLT3 and c-Kit play important roles in a variety of cellular processes. A number of SH2-domain containing proteins interact with FLT3 and c-Kit and regulate downstream signaling. The SH2-domain containing non-receptor protein tyrosine kinase CSK is mainly studied in context of regulating Src family kinases. Here we present an addition role of this kinase

Transcription factor Nurr1 maintains fiber integrity and nuclear-encoded mitochondrial gene expression in dopamine neurons

Developmental transcription factors important in early neuron specification and differentiation often remain expressed in the adult brain. However, how these transcription factors function to mantain appropriate neuronal identities in adult neurons and how transcription factor dysregulation may contribute to disease remain largely unknown. The transcription factor Nurr1 has been associated with Pa

Familial risk of early and late onset cancer : nationwide prospective cohort study.

To determine whether familial risk of cancer is limited to early onset cases. Nationwide prospective cohort study. SETTING : Nationwide Swedish Family-Cancer Database. All Swedes born after 1931 and their biological parents, totalling >12.2 million individuals, including >1.1 million cases of first primary cancer. Familial risks of the concordant cancers by age at diagnosis. The highest familial r

Wound edge microvascular blood flow during negative-pressure wound therapy: examining the effects of pressures from -10 to -175 mmHg.

BACKGROUND: Negative-pressure wound therapy is believed to accelerate wound healing by altered wound edge microvascular blood flow. The current standard negative pressure is -125 mmHg. However, this pressure may cause pain and ischemia and often has to be reduced. The aim of the present study was to examine the blood flow effects of different levels of negative pressures (-10 to -175 mmHg). METHOD

Signatures of selection acting on the innate immunity gene Toll-like receptor 2 (TLR2) during the evolutionary history of rodents.

Patterns of selection acting on immune defence genes have recently been the focus of considerable interest. Yet, when it comes to vertebrates, studies have mainly focused on the acquired branch of the immune system. Consequently, the direction and strength of selection acting on genes of the vertebrate innate immune defence remain poorly understood. Here, we present a molecular analysis of selecti

Clonal variegation and dynamic competition of leukemia-initiating cells in infant acute lymphoblastic leukemia with MLL rearrangement.

Distinct from most other acute lymphoblastic leukemia (ALL), infant ALL with mixed lineage leukemia (MLL) gene rearrangement, the most common leukemia occurring within the first year of life, might arise without the need for cooperating genetic lesions. Through Ig/TCR rearrangement analysis of MLL-AF4+ infant ALL at diagnosis and xenograft leukemias from mice transplanted with the same diagnostic