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Ecological opportunity and upward prey-predator radiation cascades

A general goal in community ecology and evolutionary biology is to understand how diversity has arisen. In our attempts to reach such goals we become increasingly aware of interacting ecological and evolutionary processes shaping biodiversity. Ecological opportunity and adaptive radiations can, for example, drive diversification in competitive communities but little is known about how such process

Diffusion of Open Source ERP Systems Development: How Users Are Involved

Open Source receives high attention among organizations today, and there is also a growing interest on Open Source Enterprise Resource Planning (OS ERP) systems. Open source development is often considered having a high level of involvement from stakeholders in adopting organizations. However, it depends on for the first what is meant by stakeholders, but also what is meant by involvement. In the

Opposites attract. Unions between majority natives and marriage migrants in Sweden : L’attraction des opposés. Mariages entre Suédois(es) et personnes qui migrent en Suède pour se marier

Marriage with the prospect of migration may lead to new patterns of union formation in globalized marriage markets. Annika Elwert looks at characteristics and marriage patterns of majority natives who are in unions with immigrants who either lived in the country before union formation or migrated around the time of marriage, and gives insights about majority natives’ openness towards different imm

The Experience of Using Video Support in Ambulance Care : An Interview Study with Physicians in the Role of Regional Medical Support

Background: In order to facilitate more effective patient assessment and diagnostic support by improving the flow of information between ambulance nurses (AN) and physicians in the role of regional medical support (RMS), an application was developed for transmitting real-time video images. Objective: The objective of this study was to elucidate the physicians' experiences using a video application

Sociodemographic factors associated with HbA1c variability in type 2 diabetes: a prospective exploratory cohort study

BackgroundThe associations between sociodemographic factors and HbA1c variability in type 2 diabetes are not yet established. Examining group differences in HbA1c variability may help identify patient characteristics related to diabetes management. The present study examined differences in baseline HbA1c and HbA1c variability between groups with regard to sex, level of education, civil status, age

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OBJECTIVE: To verify, in an open study, the efficacy and safety of long-term administration of low weekly doses (5 mg) of methotrexate (MTX) i.m. in different stage rheumatoid arthritis patients.PATIENTS AND METHODS: The study has been performed for 24 months in 42 patients (37 females and 5 males), fulfilling the ARA criteria for rheumatoid arthritis. Main functional parameters, main serological

Growth responses of a green alga to multiple environmental drivers

One feature of global change is that biota must respond not to single, but to multiple environmental drivers. By growing a model photosynthetic microbe in environments containing between one and eight different drivers, including changes in CO 2, temperature, and pH, in different combinations, we show that the number as well as the identities of drivers explain shifts in population growth rates. T

Managing choice uncertainties in life-cycle assessment as a decision-support tool for building design : A case study on building framework

To establish a circular economy in society, it is crucial to incorporate life-cycle studies, such as life-cycle assessment (LCA), in the design process of products in order to mitigate the well-recognized problem of the design paradox. The aim of the study was to provide means in a structured way to highlight choice uncertainty present in LCA when used as decision support, as well as to mitigate s

Anti-rheumatic treatment and prosthetic joint infection : An observational study in 494 elective hip and knee arthroplasties

Background: Surgical site infections are more frequent among patients with rheumatic disease. To what extent this is related to immunosuppressive antirheumatic drugs is unclear, as is the value of discontinuing medication perioperatively. The aim of study was to assess the rate of surgical site infections after knee and hip replacement in patients with inflammatory joint disease, with an emphasis

Countergradient Variation in Reptiles : Thermal Sensitivity of Developmental and Metabolic Rates Across Locally Adapted Populations

Environmental temperature is a key driver of variation in developmental physiological rates in reptiles. Cooler temperatures extend development time and can increase the amount of energy required to achieve hatching success, which can pose fitness consequences later in life. Yet, for locally-adapted populations, genetic variation can oppose environmental variation across ecological gradients, know

Experimental methods for measuring the breakup frequency in turbulent emulsification : A critical review

The growing interest in using population balance modeling to describe emulsification processes has spurred an interest in experimentally measuring the breakup frequency. This contribution classifies, compares, and critically reviews the different methods that have been suggested for measuring the breakup frequency, applicable to emulsification devices. Two major approaches can be seen in previous

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Critical discussion of proposed Dutch real estate tax exemption for first time home buyers and the negative effects for the housing market and equality of the existing gift tax exemption related to residential real estate.

Differential effects of the cystic fibrosis lung inflammatory environment on mesenchymal stromal cells

Growing evidence demonstrates that human mesenchymal stromal cells (MSCs) modify their in vivo anti-inflammatory actions depending on the specific inflammatory environment encountered. Understanding this better is crucial to refine MSC-based cell therapies for lung and other diseases. Using acute exacerbations of cystic fibrosis (CF) lung disease as a model, the effects of ex vivo MSC exposure to

Epigenome-wide gene-age interaction analysis reveals reversed effects of PRODH DNA methylation on survival between young and elderly early-stage NSCLC patients

DNA methylation changes during aging, but it remains unclear whether the effect of DNA methylation on lung cancer survival varies with age. Such an effect could decrease prediction accuracy and treatment efficacy. We performed a methylation-age interaction analysis using 1,230 early-stage lung adenocarcinoma patients from five cohorts. A Cox proportional hazards model was used to investigate lung