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A Modified Sub-Cell-Fix Method for Re-Initialization of Level-Set Distance Function and Its Dependence Tests on Grid Stretching

The sub-cell-fix (SCF) method proposed by Russo and Smereka(3) computes the distance function of the cells adjacent to the zero level-set without disturbing the original zero level-set. A modified sub-cell-fix scheme independent of local curvature is developed in this paper, which makes use of a combination of the points adjacent to zero level-set surfaces and preserves the interface in a second-o

Characterization of human papillomavirus type 154 and tissue tropism of gammapapillomaviruses.

The novel human papillomavirus type 154 (HPV154) was characterized from a wart on the crena ani of a three-year-old boy. It was previously designated as the putative HPV type FADI3 by sequencing of a subgenomic FAP amplicon. We obtained the complete genome by combined methods including rolling circle amplification (RCA), genome walking through an adapted method for detection of integrated papillom

On the origin of phylogenetic structure in competitive metacommunities

Question: Under what circumstances are local communities and metacommunities phylogenetically clustered, overdispersed or random assemblages in terms of phylogenetic relatedness? Methods: An individual-based eco-evolutionary model was used to explain the link between system properties, ecological and evolutionary processes, and phylogenetic patterns in a spatially explicit competitive metacommunit

Evaluation of macroporous blood and plasma scaffolds for skeletal muscle tissue engineering

The field of tissue engineering has a growing need for suitable scaffold materials to become attractive as a clinical therapy. To use a completely autologous construct to repair a damaged or diseased tissue is an appealing thought. As a model system, two types of scaffolds were prepared from biological fluids: blood and plasma. The prepared scaffolds formed a macroporous structure with elastic mec

Patients with coronary artery disease and diabetes need improved management: a report from the EUROASPIRE IV survey: a registry from the EuroObservational Research Programme of the European Society of Cardiology.

In order to influence every day clinical practice professional organisations issue management guidelines. Cross-sectional surveys are used to evaluate the implementation of such guidelines. The present survey investigated screening for glucose perturbations in people with coronary artery disease and compared patients with known and newly detected type 2 diabetes with those without diabetes in term

Water quality and non-point sources of risk: the Jiulong River Watershed, P. R. of China.

Retrospective water quality assessment plays an essential role in identifying trends and causal associations between exposures and risks, thus it can be a guide for water resources management. We have developed empirical relationships between several time-varying social and economic factors of economic development, water quality variables such as nitrate-nitrogen, COD(Mn), BOD(5), and DO, in the J

Binding affinities in the SAMPL3 trypsin and host-guest blind tests estimated with the MM/PBSA and LIE methods.

We have estimated affinities for the binding of 34 ligands to trypsin and nine guest molecules to three different hosts in the SAMPL3 blind challenge, using the MM/PBSA, MM/GBSA, LIE, continuum LIE, and Glide score methods. For the trypsin challenge, none of the methods were able to accurately predict the experimental results. For the MM/GB(PB)SA and LIE methods, the rankings were essentially rand

Spatially Coupled Protograph-Based LDPC Codes for Incremental Redundancy

We investigate a family of protograph based rate-compatible LDPC convolutional codes. The code family shows improved thresholds close to the Shannon limit compared to their uncoupled versions for the binary erasure channel as well as the AWGN channel. In fact, the gap to Shannon limit is almost uniform for all members of the code family ensuring good performance for all subsequent incremental redu

Detrusor Induction of miR-132/212 following Bladder Outlet Obstruction: Association with MeCP2 Repression and Cell Viability.

The microRNAs (miRNAs) miR-132 and miR-212 have been found to regulate synaptic plasticity and cholinergic signaling and recent work has demonstrated roles outside of the CNS, including in smooth muscle. Here, we examined if miR-132 and miR-212 are induced in the urinary bladder following outlet obstruction and whether this correlates with effects on gene expression and cell growth. Three to seven

Tests of multiple molecular markers for the identification of Great Spotted and Syrian Woodpeckers and their hybrids

Great Spotted and Syrian Woodpeckers (Dendrocopos major and D. syriacus) are known to hybridize in nature; however, the extent of this phenomenon is not known due to difficulties in hybrid detection based on plumage analyses. Here, we tested five markers (one mitochondrial and four nuclear) and a set of six microsatellite loci for the identification of these two Woodpeckers and their hybrids. Sequ

Results of the Scandinavian Sarcoma Group XIV protocol for classical osteosarcoma 63 patients with a minimum follow-up of 4 years

Background and purpose The Scandinavian Sarcoma Group (SSG) XIV protocol is based on experience from previous SSG trials and other osteosarcoma intergroup trials, and has been considered the best standard of care for patients with extremity localized, non-metastatic osteosarcoma. We analyzed the outcome in 63 consecutive patients. Patients and methods From 2001 through 2005, 63 patients recruited

Woody biomass-based transportation fuels – A comparative techno-economic study

Production of synthetic vehicle fuels from biomass is a hot topic. There are several alternative fuels to consider when evaluating properties such as cost of production and energy efficiency to both product and final use in a road vehicle. Thermochemical conversion via gasification and downstream synthesis of fuels as well as biochemical conversion of woody biomass to ethanol is considered in this

Gene therapy for epilepsy: resculpturing synaptic transmission with neuropeptides

Intractable seizures and lack of effective antiepileptic drugs (AED) are severe and common conditions affecting many patients with epilepsy. Thus, there is an urgent need to develop new therapies in epilepsy. The search for novel treatments has identified several neuropeptide systems as potential targets for future therapeutic interventions. The neuropeptide Y (NPY) may represent one such target,

Entrepreneurship research in three regions-the USA, Europe and China

During the last few decades the field of entrepreneurship has received increased scholarly attention all over the world. Nevertheless, against this internationalization background, little is known about how entrepreneurship research developed in different regions. In this study, we illustrate the development of entrepreneurship field not only in the USA and Europe but also in China. The study is b

Determination of residual stresses around blisters in Zr-2.5%Nb pressure tubes

We have used synchrotron X-ray diffraction experiments to measure the strain field introduced by a hydride blister grown on a section of a pressure tube from a CANDU nuclear reactor. After charging the tube section with a homogeneous hydrogen concentration of 300 wt ppm, the blister was produced by creating a small cold spot on its surface (similar to 200 degrees C), while the bulk was kept at a t

Influence of host genetics on innate immunity and susceptibility to urinary tract infection

It has been known for a long time that the clinical manifestations of urinary tract infections (UTI) differ markedly between individuals, ranging from a sometimes beneficial, asymptomatic state to life threatening infections. This variability in clinical manifestation can be explained in part by the arsenal of virulence factors of the bacteria but the predisposition of the patient is equally impor

How mankind has shaped European nature

A monographic book volume on the history of the rural landscape of Europe is presented (Emanuelsson, The rural landscape of Europe. How man has shaped European nature, 383, 2009). The focus is on various land-use phases, their history from the Neolithic period to modern time and the survival of traditional farming today in Europe. This is described and illustrated by examples from marginal farming