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A screening procedure detecting high-yield candidates for OGTT. The Women's Health in the Lund Area (WHILA) study: a population based study of middle-aged Swedish women

The objective was to evaluate a screening procedure for detecting high-yield candidates for an OGTT, in a population of middle-aged Swedish women. A two-step screening procedure was performed in 6917 subjects. Women with a positive screening outcome, i.e. increased non-fasting capillary blood glucose, serum triglycerides, BMI, WHR, blood pressure or a family history of diabetes, pharmacological tr

The quality assurance process for the ARTSCAN head and neck study - A practical interactive approach for QA in 3DCRT and IMRT

Aim: This paper describes the quality assurance (QA) work performed in the Swedish multicenter ARTSCAN (Accelerated RadioTherapy of Squamous cell CArcinomas in the head and Neck) trial to guarantee high quality in a multicenter study which involved modern radiotherapy such as 3DCRT or IMRT. Materials and methods: The study was closed in June 2006 with 750 randomised patients. Radiation therapy-rel

Stereoisomeric composition of the sex pheromone of the pine sawfly Microdiprion pallipes (Hym., Diprionidae)

The basic chemical structure of the sex pheromone of the pine sawfly Microdiprion pallipes (Fallen) has earlier been identified as the propionate ester of (2S,3S,7 R/S,11 R/S)/(2R,3R,7 R/S,11 R/S)-3,7,11-trimethyl-2-tridecanol. We now report the results from further investigations on the male response to individual stereoisomers and to blends of stereoisomers, both in electroantennographic (EAG) r

How the walls come crumbling down: recent structural biochemistry of plant polysaccharide degradation

The recent years have witnessed considerable developments in the interpretation of the three-dimensional structures of plant polysaccharide-degrading enzymes in the context of their functional specificity. A plethora of new structures of catalytic, carbohydrate-binding and protein-scaffolding modules involved in (hemi)cellulose catabolism has emerged in harness with sophisticated biochemical analy

Bone graft incorporation. Effects of osteogenic protein-1 and impaction

Impaction of cancellous bone grafts in a bone chamber in rats in a previous study led to decreased ingrowth of new bone after 6 weeks compared with unimpacted grafts. The current study analyzes whether this decrease represented a final loss of ingrowth or just a delay, if the decrease was influenced by immunologic factors, and if it was possible to influence the inhibitory effect by adding a bone

Oxford meniscal bearing knee versus the Marmor knee in unicompartmental arthroplasty for arthrosis. A Swedish multicenter survival study

In the Swedish Knee Arthroplasty Study, all 699 Oxford meniscal bearing cemented unicompartmental prostheses (Biomet, Bridgend, UK) were identified and analyzed regarding failure pattern and compared with all Marmor prostheses (Smith & Nephew Richards, Orthez, France) and with a time-, age-, and sex-matched subset of Marmor prostheses using survival statistics expressed as cumulative revision

Mother's Genome or Maternally-Inherited Genes Acting in the Fetus Influence Gestational Age in Familial Preterm Birth

Objective: While multiple lines of evidence suggest the importance of genetic contributors to risk of preterm birth, the nature of the genetic component has not been identified. We perform segregation analyses to identify the best fitting genetic model for gestational age, a quantitative proxy for preterm birth. Methods: Because either mother or infant can be considered the proband from a preterm

Significance of hyphal diameter in calculation of fungal bio-volume

Three ways to calculate average hyphal cross section in agarfilm slides were compared in a field study including 5 soil horizons sampled 4 times. The method of calculation strongly affected the estimated value for soil fungal biovolume. Biovolume estimated with the different methods varied by more than 30%. Great differences in average cross section were found between the soil horizons, stressing

Complement regulation in human atherosclerotic coronary lesions - Immunohistochemical evidence that C4b-binding protein negatively regulates the classical complement pathway, and that C5b-9 is formed via the alternative complement pathway

Objective: The complement system is activated in human atherosclerotic lesions and may hence aggravate local inflammation. We studied the presence and localization of C4b-binding protein (C4bp), the major inhibitor of the classical complement pathway, in human atherosclerotic lesions in relation to complement activation products and protein S, which circulates in complex with C4bp. Methods and res

Screening and selection of Lactobacillus strains for use as adjunct cultures in production of semi-hard cheese

Thirty-three Lactobacillus strains were tested as adjuncts in a cheese model system. Eighteen strains originated from cheese (nine Lactobacillus spp. and nine Lb. paracasei/casei) and 15 from human intestinal mucosa (11 Lb. rhamnosus; three Lb. paracasei; one Lb. plantarum). Model cheeses weighing 120 g were made of cheese grains from full-scale production of washed curd semi-hard cheese (Herrgard

Interference of 7-hydroxymethotrexate with the determination of methotrexate in plasma samples from children with acute lymphoblastic leukemia employing routine clinical assays

The accuracy of two clinical assays, the enzyme-multiplied immunoassay (EMIT) and fluorescence polarization immunoassay (FPIA2), universally employed for measurement of plasma levels of methotrexate (MTX) in children administered a high dose of this drug for treatment of acute lymphoblastic leukemia was evaluated here. Because of its superior specificity, sensitivity, and precision, high performan

Characteristics of gel electrolytes formed by self-aggregating comb-shaped polyethers with end-functionalised side chains

Gel electrolytes based on comb-shaped polyethers have been prepared and characterised. The comb-shaped polyethers consisted of poly(ethylene oxide) (PEO) or poly(ethylene oxide-co-propylene oxide) (PEOPO) side chains tethered to styrenic backbone polymers. All the polyether side chains were terminated by hydrocarbon (C-16) chain ends. Polymer gel electrolytes were prepared by adding 10-70 wt.% of

Respiratory Tract Deposition of Particles from Biomass Combustion

The respiratory tract deposition of particles from two types of biomass combustion was measured for 10 healthy subjects. The aerosol was extensively characterised. Model calculations of the deposition were made based on the particle properties. The results show that particle water absorption has substantial impact on deposition. The particles from biomass combustion obtained a size in the respirat

Solving dimensioning tasks for proportionally fair networks carrying elastic traffic

The paper studies optimal dimensioning problems associated with the notion of “proportional fairness” (PF) considered for packet networks carrying elastic (greedy) traffic, i.e. the traffic streams that can use up, perhaps within certain assumed bounds, any bandwidth that is assigned to them. We give effective, simple and explicit solutions to the introduced optimisation tasks based on the dual op

Interaction of cartilage matrix protein with aggrecan. Increased covalent cross-linking with tissue maturation

Cartilage matrix protein (CMP) is a trimeric protein present in many types of cartilage extracellular matrix. It has recently been purified under native conditions that allowed the proposal of a structural model (Hauser, N., and Paulsson, M. (1994) J. Biol. Chem. 269, 25747-25753). To examine the functional properties of CMP we studied its interaction with aggrecan within cartilage extracellular m

Dynamic evaluation of integrated control strategies for enhanced nitrogen removal in activated sludge processes

In this paper, six different strategies for integrated control of nitrate recirculation flow rate and external carbon addition in a predenitrifying biological wastewater treatment system are proposed and evaluated using the COST simulation benchmark. The proposed control strategies consist of two or three feedback control loops, which manipulate the nitrate recirculation and the carbon dosage flow