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Target-Attainment Rates of Low-Density Lipoprotein Cholesterol Using Lipid-Lowering Drugs One Year After Acute Myocardial Infarction in Sweden

The objective of this prospective cohort study was to describe real-life use of lipid-lowering drugs and low-density lipoprotein cholesterol (LDL-C) target-attainment rates 1 year after acute myocardial infarction (AMI). LDL-C was recorded at hospital admission for AMI and at follow-up at 2 and 12 months after AMI in 17,236 patients in the Swedish heart registry, SWEDEHEART, from 2004 through 2009

Implicit stereotype content: Mixed stereotypes can be measured with the Implicit Association Test

The stereotype content model (SCM) postulates that stereotype content can be mixed in terms of diverging evaluations on the warmth and competence dimensions. The present study is the first to demonstrate this with implicit measures. Two Implicit Associations Tests (IATs) were developed, one capturing the warmth dimension and the other the competence dimension. Both IATs compared preschool teachers

Electronic structures of [001]- and [111]-oriented InSb and GaSb free-standing nanowires

We report on a theoretical study of the electronic structures of InSb and GaSb nanowires oriented along the [001] and [111] crystallographic directions. The nanowires are described by atomistic, tight-binding models, including spin-orbit interaction. The band structures and the wave functions of the nanowires are calculated by means of a Lanczos iteration algorithm. For the [001]-oriented InSb and

Intercalation of smectite with liquid ethylene glycol - Resolved in time and space by synchrotron X-ray diffraction

Using synchrotron X-ray powder diffraction we studied the reaction of liquid ethylene glycol and smectite, i.e. (i) the time-resolved glycolation of Mg-smectite (Georgian Ibeco Seal M-90) films equilibrated to form hydrates with 0-3 water layers, and (ii) time and spatially resolved glycolation of homoionic Li-, Na-, K-, Mg-, and Ca-montmorillonite powders (Wyoming MX80) equilibrated to ambient at

Long-term Mobile Phone Use and Acoustic Neuroma Risk.

There is concern about potential effects of radiofrequency fields generated by mobile phones on cancer risk. Most previous studies have found no association between mobile phone use and acoustic neuroma, although information about long-term use is limited.

Relationship Between Serum Response Factor and Androgen Receptor in Prostate Cancer

BACKGROUND. Serum response factor (SRF) is an important transcription factor in castrate-resistant prostate cancer (CRPC). Since CRPC is associated with androgen receptor (AR) hypersensitivity, we investigated the relationship between SRF and AR. MATERIALS AND METHODS. Transcriptional activity was assessed by luciferase assay. Cell proliferation was measured by MTT and flow cytometry. Protein expr

Incidence Trends of Squamous Cell and Rare Skin Cancers in the Swedish National Cancer Registry Point to Calendar Year and Age-Dependent Increases

Little is known regarding the incidence trends of squamous cell skin carcinoma (SCC) and rare skin tumors, including Merkel cell carcinoma (MCC) and dermatofibrosarcoma protuberans (DFSP). The purpose of this study was to examine recent incidence trends for these cancers from 1990 to 2005 using the population-based Swedish National Cancer Registry. SCC incidence increased significantly over the st

Phase diagram of a rapidly rotating two-component Bose gas

We derive analytically the phase diagram of a two-component Bose gas confined in an anharmonic potential, which becomes exact and universal in the limit of weak interactions and small anharmonicity of the trapping potential. The transitions between the different phases, which consist of vortex states of single and multiple quantization, are all continuous because of the addition of the second comp

Low-Complexity Uncertainty-Set-Based Robust Adaptive Beamforming for Passive Sonar

Recent work has highlighted the potential benefits of exploiting ellipsoidal uncertainty-set-based robust Capon beamformer (RCB) techniques in passive sonar. Regrettably, the computational complexity required to form RCB weights is cubic in the number of adaptive degrees of freedom, which is often prohibitive in practice. For this reason, several low-complexity techniques for computing RCB weights

Temporal Changes in the Quality of Acute Stroke Care in Five National Audits across Europe

Background. Data on potential variations in delivery of appropriate stroke care over time are scarce. We investigated temporal changes in the quality of acute hospital stroke care across five national audits in Europe over a period of six years. Methods. Data were derived from national stroke audits in Germany, Poland, Scotland, Sweden, and England/Wales/Northern Ireland participating within the E

Plasma Volume Expansion by 0.9% NaCl During sepsis/SIRS, After Hemorrhage, and During a Normal State.

OBJECTIVE: To determine the degree of plasma volume expansion by 0.9% NaCl in relation to the infused volume, in sepsis/SIRS (systemic inflammatory response syndrome), after a standardized hemorrhage, and in a normal condition. DESIGN: Prospective, randomized animal study. SETTING: University hospital laboratory. SUBJECTS: Thirty anesthetized adult male rats. INTERVENTIONS: The study was performed

Inhibition of MicroRNA-125a Promotes Human Endothelial Cell Proliferation and Viability through an Antiapoptotic Mechanism.

The microRNA-125a (miR-125a) is highly expressed in endothelial cells, but its role in vascular biology is not known. Endothelial cell proliferation and viability play an important role in endothelial healing, and we hypothesize that miR-125a regulates this process. The aim of the present study was to investigate if miR-125a controls human endothelial cell proliferation, viability and endothelial

Influence of Melatonin on the Proliferative and Apoptotic Responses of the Prostate under Normal and Hyperglycemic Conditions.

The antitumor properties of melatonin (MLT) are known for prostate cancer cells. This study investigated whether MLT affects prostate maturation and interferes with tissue injuries induced by diabetes. MLT was administered to Wistar rats from 5 weeks of age in the drinking water (10 μg/kg b.w.), and diabetes was induced at the 13th week by streptozotocin (4.5 mg/100g b.w., i.p.). The animals were

Mutated cylindromatosis gene affects the functional state of dendritic cells

Cylindromatosis gene (CYLD) is a ubiquitously expressed deubiquitinating enzyme, which interacts with members of the NF-kappa B signaling pathway and attenuates NF-kappa B and JNK signaling. Here, we report that DC derived from transgenic mice, which solely express a naturally occurring CYLD isoform (CYLDex7/8), display a higher content of nuclear RelB and express elevated levels of NF-kappa B fam

Measurement of the top quark pair production charge asymmetry in proton-proton collisions at root s=7 TeV using the ATLAS detector

This paper presents a measurement of the top quark pair () production charge asymmetry A (C) using 4.7 fb(-1) of proton-proton collisions at a centre-of-mass energy root s = 7 TeV collected by the ATLAS detector at the LHC. A -enriched sample of events with a single lepton (electron or muon), missing transverse momentum and at least four high transverse momentum jets, of which at least one is tagg