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Continuous hiv-1 escape from autologous neutralization and development of cross-reactive antibody responses characterizes slow disease progression of children
The antibodies with different effector functions evoked by Human Immunodeficiency Virus type 1 (HIV-1) transmitted from mother to child, and their role in the pathogenesis of infected children remain unresolved. So, too, the kinetics and breadth of these responses remain to be clearly defined, compared to those developing in adults. Here, we studied the kinetics of the autologous and heterologous
Symptom clusters in COVID-19 : A potential clinical prediction tool from the COVID Symptom Study app
As no one symptom can predict disease severity or the need for dedicated medical support in coronavirus disease 2019 (COVID-19), we asked whether documenting symptom time series over the first few days informs outcome. Unsupervised time series clustering over symptom presentation was performed on data collected from a training dataset of completed cases enlisted early from the COVID Symptom Study
Translating Luther into Swedish in the Sixteenth Century
This article investigates the production of religious literature published in Swedish from 1520 to 1599, specifically looking for translations of Luther’s texts. Previous research has concluded that Luther was relatively absent from the Swedish book market during the sixteenth Century – apart from translations of the Small Catechism and his Bible. In order to challenge previous research, the artic
Prevalence and diversity of avian haemosporidians may vary with anthropogenic disturbance in tropical habitats in myanmar
Avian malaria and related haemosporidians (genera Haemoproteus, Plasmodium and Leu-cocytozoon) infect most clades of bird. Although these parasites are present in almost all continents, they have been irregularly studied across different geographical regions. Despite the high bird diversity in Asia, the diversity of avian haemosporidians in this region is largely unknown. Moreover, anthropogenic c
Production of light-flavor hadrons in pp collisions at √s=7and√s=13TeV
The production of π±, K ±, KS0, K ∗(892) , p , ϕ(1020) , Λ , Ξ -, Ω -, and their antiparticles was measured in inelastic proton–proton (pp) collisions at a center-of-mass energy of s = 13 TeV at midrapidity (| y| < 0.5) as a function of transverse momentum (pT) using the ALICE detector at the CERN LHC. Furthermore, the single-particle pT distributions of KS0, Λ , and Λ ¯ in inelastic pp collisions
NTRK Alterations in pediatric high-risk malignancies identified through European clinical sequencing programs constitute promising drug targets
Methylxanthine for the prevention and treatment of apnea in preterm infants [Protocol]
Objectives: This is a protocol for a Cochrane Review (intervention). The objectives are as follows:. To determine the effects of methylxanthine administration on the incidence of apnea and longer-term clinical outcomes in preterm infants including infants at risk for or having apnea and preterm infants peri-extubation.
Physical activity and health-related quality of life in men and women with hip and/or knee osteoarthritis before and after a supported self-management programme–a prospective observational study
Purpose: To study differences between men and women in physical activity (PA) and health-related quality of life (HRQoL) before and after participating in a supported osteoarthritis (OA) self-management programme. Materials and methods: A prospective observational study using data from a Swedish National Quality Register. Patients recorded between 2008 and 2013 with hip and/or knee OA with data at
The Protein Corona Leads to Deformation of Spherical Micelles
The formation of a non-specific protein corona around nanoparticles (NPs) has been identified as one of the culprits for failed nanomedicine. The amount and type of adsorbed protein from the blood plasma are known to determine the fate of NPs and the accessibility of targeting ligands. Herein, we show that the adsorbed protein may not only enlarge the NPs and change their surface properties but al
Cocamidopropyl betaine, cocamidopropylamine oxide, and disodium cocoamphodiacetate cause false-positive reactions with an isothiazolinone spot test
Några kompletterande reflektioner om EU-rättens påverkan på nordiskt samarbete inom upphovsrättens område
Multiple-Biomarker Panel Estimated GFR Is Not Optimal or Cost-Effective
Participation in social and leisure activities while re-constructing the self : understanding strategies used by stroke survivors from a long-term perspective
Purpose: To further understand social and leisure (SL) participation after stroke and how it can be supported in a long-term perspective, this study aims to deepen the understanding of strategies used by long-term stroke survivors in relation to SL activities. Materials and methods: The study has a qualitative design, using a grounded theory approach, and is based on in-depth interviews with 10 pe
Is meniscal status in the anterior cruciate ligament injured knee associated with change in bone surface area? An exploratory analysis of the KANON trial
Objectives: To study bone shape changes as a potential early feature of post-traumatic structural knee OA development, we estimated the association between meniscal status in the anterior cruciate ligament (ACL) injured knee and longitudinal condyle changes in bone surface area. Design: We used data from the KANON trial, including 121 young ACL-injured adults. We obtained baseline and 2-year follo
Recovery at work as a health-promoting process
The purpose of this thesis was to deepen the understanding of recovery during the workday and its importance for employee health. Workplace intervention as a tool to promote employees’ experience of recovery was also evauated.The studies were carried out in a primary health care setting in one health care district in Sweden between 2013 and 2019, together with the employees working at the 26 parti
Tradeoffs in expressed major histocompatibility complex diversity seen on a macro‐evolutionary scale among songbirds
To survive organisms must defend themselves against pathogens. Classical Major Histocompatibility Complex (MHC) genes play a key role in pathogen defense by encoding molecules involved in pathogen recognition. MHC gene diversity influences the variety of pathogens individuals can recognize and respond to and has consequently been a popular genetic marker for disease resistance in ecology and evolu
Lean Construction Principles and Railway Maintenance Planning
Lean construction principles have been successfully adopted in a variety of industries to increase project management quality. This paper addresses maintenance planning in Sweden and analyses its effectiveness in the framework of lean construction principles. To investigate the status and improvement potential of maintenance contractors’ performance, the study focuses on the detailed planning proc
Mitigation of pretreatment-derived inhibitors during lignocellulosic ethanol fermentation using spent grain as a nitrogen source
Nitrogen-containing nutrient sources can be used to mitigate the negative effects of pretreatment-derived inhibitors on product formation rates during bioethanol production. Process economic limitations require these nutrients to be inexpensive. A method of hydrolyzing the protein in the spent grain fraction remaining after wheat grain saccharification, using porcine pancreas trypsin, is presented
An extensive parameter study of hydrotropic extraction of steam-pretreated birch
Efficient fractionation of lignocellulosic biomass is an important step toward the replacement of fossil-based products. However, the utilisation of all of the components in biomass requires various fractionation techniques. One promising process configuration is to apply steam explosion for the recovery of hemicelluloses and a subsequent hydrotropic extraction step for the delignification of the