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Electron-Poor Iridium Pincer Complexes as Dehydrogenation Catalysts : Investigations into Deactivation through Formation of N2, CO, and Hydride Complexes

A range of derivatives of an iridium pincer complex with a bis-trifluoromethyl-substituted ligand have been studied to determine how their properties differ from those of similar systems. The emphasis is on derivatives valuable for catalytic acceptorless dehydrogenation, including intermediates and deactivation products. The studies highlight small but important differences in the electron richnes

Single-cell RNA sequencing of aging neural progenitors reveals loss of excitatory neuron potential and a population with transcriptional immune response

In the adult murine brain, neural stem cells (NSCs) can be found in two main niches: the dentate gyrus (DG) and the subventricular zone (SVZ). In the DG, NSCs produce intermediate progenitors (IPs) that differentiate into excitatory neurons, while progenitors in the SVZ migrate to the olfactory bulb (OB), where they mainly differentiate into inhibitory interneurons. Neurogenesis, the process of ge

Formation Mechanism and Hydrothermal Synthesis of Highly Active Ir1-xRuxO2 Nanoparticles for the Oxygen Evolution Reaction

Iridium dioxide (IrO2), ruthenium dioxide (RuO2), and their solid solutions (Ir1-xRuxO2) are very active electrocatalysts for the oxygen evolution reaction (OER). Efficient and facile synthesis of nanosized crystallites of these materials is of high significance for electrocatalytic applications for converting green energy to fuels (power-to-X). Here, we use in situ X-ray scattering to examine rea

Scarabaeolus carniphilus : a necrophagous dung beetle (Coleoptera: Scarabaeinae) buries and feeds on a dead snake

A rare sighting of two male carrion specialist dung beetles, Scarabaeolus carniphilus Deschodt & Davis, 2015, burying a freshly dead Herald snake (Crotaphopeltis hotamboeia (Laurenti, 1768)) is documented from its discovery in the field and subsequent reburial under laboratory conditions. The species studied is a member of the telecoprid (dung roller) Scarabaeini, but behaved here like a parac

A National Cohort with Aneurysmal Subarachnoid Hemorrhage—Patient Characteristics, Choice of Treatment, Clinical Outcome, and Factors of Prognostic Importance

Objective: To study associations of clinical characteristics and treatment choice with functional outcome, mortality, and time to death in a national sample of aneurysmal subarachnoidal hemorrhage patients. Methods: Data were extracted from a prospective nationwide multicenter study performed in September 2014 to March 2018. Glasgow Outcome Scale Extended (GOSE) grade, 1-year mortality, and surviv

Structural Variants in the SMC1A Gene Associated With Near-Haploidy in Undifferentiated Pleomorphic Sarcomas

Near-haploidization, that is, loss of one copy of most chromosomes, is a relatively rare phenomenon in most tumors, but is enriched among certain soft tissue sarcomas, including undifferentiated pleomorphic sarcoma (UPS). Presumably, near-haploidization can arise through many mechanisms. This study aimed to identify gene rearrangements that could cause near-haploidization. We here present two UPS

“In Practice, It Just Happens” : 1: How the Nordics Work Together Within Peace and Conflict Resolution

The chapter examines what peace looks like from the working levels of the Nordic countries. Several researchers have proclaimed a common Nordic approach to peace and conflict resolution “dead”. However, through interviews focusing on the working level, we find that the Nordics in fact work very closely together in practice, especially in the field in conflict-affected areas. This work is generally

Proteomic changes in Alzheimer’s disease associated with progressive Aβ plaque and tau tangle pathologies

Proteomics can shed light on the dynamic and multifaceted alterations in neurodegenerative disorders like Alzheimer’s disease (AD). Combining radioligands measuring β-amyloid (Aβ) plaques and tau tangles with cerebrospinal fluid proteomics, we uncover molecular events mirroring different stages of AD pathology in living humans. We found 127 differentially abundant proteins (DAPs) across the AD spe

The impact of a crisis on the provision of assistive technology in Sweden : the case of COVID-19

The entitlement to access assistive technology (AT) is fundamental for all individuals. However, challenges encountered during societal crises can significantly impact opportunities for participation and engagement among AT users. Understanding the implications of crises and disasters on AT provision along with their repercussions for end users is crucial. This research endeavors to investigate thThe entitlement to access assistive technology (AT) is fundamental for all individuals. However, challenges encountered during societal crises can significantly impact opportunities for participation and engagement among AT users. Understanding the implications of crises and disasters on AT provision along with their repercussions for end users is crucial. This research endeavors to investigate th

Towards a hierarchical user requirement structure for upper limb assistive robotics

This paper presents the results of an interdisciplinary study encompassing data collected from 108 in-depth interviews and 15 participatory workshops aimed at exploring the requirements of a diverse range of stakeholders in relation to assistive augmentative technologies. The study involved 39 poststroke patients with hand paresis, 39 individuals with spinal cord injuries affecting upper limb funcThis paper presents the results of an interdisciplinary study encompassing data collected from 108 in-depth interviews and 15 participatory workshops aimed at exploring the requirements of a diverse range of stakeholders in relation to assistive augmentative technologies. The study involved 39 poststroke patients with hand paresis, 39 individuals with spinal cord injuries affecting upper limb func

Monitoring spatiotemporal patterns in the genetic diversity of a European butterfly species

The importance of genetic diversity has been recognised by the Convention on Biological Diversity but attempts at monitoring or improving the genetic diversity of populations have been minimal. Here, we investigate changes over time in the genetic diversity of a wild insect species, Maniola jurtina (Lepidoptera: Nymphalidae) and present a large-scale investigation into contemporary spatial genetic

A critical narrative review of assistive robotics and call for a systems and user-centered approaches to enhance quality of life of individuals with disabilities

Background: Despite the rapid pace of assistive robotics development, adoption of these has been limited. This raises questions such as: What contributes to this low uptake? What strategies could be employed to increase uptake? What guidance can be found in the literature to inform alternative approaches or directions for development?Objective: This critical narrative review sheds light on the devBackground: Despite the rapid pace of assistive robotics development, adoption of these has been limited. This raises questions such as: What contributes to this low uptake? What strategies could be employed to increase uptake? What guidance can be found in the literature to inform alternative approaches or directions for development?Objective: This critical narrative review sheds light on the de-

No biggie can be a “biggie” : A taxonomical and statistical analysis of the pragmaticalization of no biggie on the basis of pragma-syntactic variation and co-occurring lexical items

This study seeks to explore the pragmaticalization process of (it's) no biggie, through a corpus-based taxonomical and statistical examination. The research study involves (i) elaborating a taxonomy of no biggie constructions by exploring the variability of the pragmatic functions and the syntactic features associated with the construction; (ii) monitoring the links between the taxonomical types o

Managing customer order decoupling points in supply chains

The concept of a customer order decoupling point (CODP) has been discussed since 1984. The CODP refers to the point in the supply chain at which a product is linked to a specific customer. Consequently, make to stock (MTS), assemble to order (ATO), make to order (MTO), purchase and make to order (PMTO), andengineer to order (ETO) all refer to different positions of the CODP. The CODP separates the

Adolescents’ Experiences of Existential Loneliness Regarding Receiving and Providing Support

Among adolescents, loneliness is common. One kind of loneliness, existential loneliness, is understood as a painful part of the human condition. During adolescence, existential loneliness has been shown to be challenging to navigate independently. Therefore, this study aimed to explore Swedish adolescents’ experiences of existential loneliness regarding receiving and providing support. This study

Scaffolding structures to promote widening participation in higher education–a meta-ethnographic analysis of qualitative studies

Introduction: Widening participation in education by including students from underrepresented groups has been recognized as important for the last decade. During the recent pandemic, the interest in how to make students from different backgrounds feel part of the university, and connected to their studies and peers, has become an even more widespread concern and therefore important to explore furt

Quality Requirements for Code : On the Untapped Potential in Maintainability Specifications

Quality requirements are critical for successful software engineering, with maintainability being a key internal quality. Despite significant attention in software metrics research, maintainability has attracted surprisingly little focus in the Requirements Engineering (RE) community. This position paper proposes a synergistic approach, combining code-oriented research with RE expertise, to create

Sulfonate and Ammonium-Grafted Poly(isatin triphenyl) Membranes for the Vanadium Redox Flow Battery

As one of the most critical components of the vanadium redox flow battery (VRFB), the ion exchange membrane directly influences the battery efficiency and cycle life. Herein, poly(isatin triphenyl) (PIT) containing a lactam structure and devoid of ether bonds is synthesized from isatin and p-terphenyl under superacid catalysis. To achieve the ion transport and investigate the impact of side chain

The genomic natural history of the aurochs

Now extinct, the aurochs (Bos primigenius) was a keystone species in prehistoric Eurasian and North African ecosystems, and the progenitor of cattle (Bos taurus), domesticates that have provided people with food and labour for millennia1. Here we analysed 38 ancient genomes and found 4 distinct population ancestries in the aurochs—European, Southwest Asian, North Asian and South Asian—each of whicNow extinct, the aurochs (Bos primigenius) was a keystone species in prehistoric Eurasian and North African ecosystems, and the progenitor of cattle (Bos taurus), domesticates that have provided people with food and labour for millennia1. Here we analysed 38 ancient genomes and found 4 distinct population ancestries in the aurochs—European, Southwest Asian, North Asian and South Asian—each of whic