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Testicular-cancer survivors experience compromised language following chemotherapy: Findings in a Swedish population-based study 3-26 years after treatment

Background. Studies suggest an increased risk for compromised cognitive function among cancer survivors. It is unclear to what extent chemotherapy is the cause and how the dysfunction, when present, affects everyday life. The objective was to study self-reported behaviours that may depend on cognitive function, among testicular-cancer survivors who received various cycles of cisplatin-based chemot

The effect of vitamin C on plasma volume in the early stage of sepsis in the rat.

Previous experimental studies have shown that vitamin C has several beneficial effects in sepsis and burns, such as decreased tissue oedema, improved endothelial barrier function and decreased transcapillary leakage of plasma markers. It has still not been investigated, though, if vitamin C has any impact specifically on plasma volume. The present study aims at testing the hypothesis that vitamin

Chemerin Is an Antimicrobial Agent in Human Epidermis

Chemerin, a chemoattractant ligand for chemokine-like receptor 1 (CMKLR1) is predicted to share similar tertiary structure with antibacterial cathelicidins. Recombinant chemerin has antimicrobial activity. Here we show that endogenous chemerin is abundant in human epidermis, and that inhibition of bacteria growth by exudates from organ cultures of primary human skin keratinocytes is largely chemer

Measurement of the cross section for the production of a W boson in association with b-jets in pp collisions at root s=7 TeV with the ATLAS detector

A measurement is presented of the cross section for the production of a W boson with one or two jets, of which at least one must be a b-jet, in pp collisions at root s = 7 TeV. Production via top decay is not included in the signal definition. The measurement is based on 35 pb(-1) of data collected with the ATLAS detector at the LHC. The W + b-jet cross section is defined for jets reconstructed wi

Health economics and its measures in rheumatoid arthritis

Popular Abstract in Swedish Reumatoid artrit Reumatoid artrit (RA), på svenska ledgångsreumatism, är den vanligaste kroniska, inflammatoriska ledsjukdomen (artriten) bland människor. I Sverige är förekomsten i befolkningen omkring 0,7%, och bland 100 000 personer insjuknar ca. 50 årligen med denna diagnos. Könsfördelningen är dock ojämn, med en mer än dubbelt så stor risk för kvinnor att utvecklaObjectives: To study: (I) the impact on cost-utility analyses of applying different national EuroQol 5-Dimensions (EQ-5D) preference sets; (II and III) whether, in methotrexate-refractory, early rheumatoid arthritis (RA), the addition of infliximab results in superior health-related quality of life (HRQoL) and may be considered cost-effective, as compared to adding sulfasalazine and hydroxychloroq

Validation of cytoplasmic-to-nuclear ratio of survivin as an indicator of improved prognosis in breast cancer

Background: Conflicting data exist regarding the prognostic and predictive impact of survivin (BIRC5) in breast cancer. We previously reported survivin cytoplasmic-to-nuclear ratio (CNR) as an independent prognostic indicator in breast cancer. Here, we validate survivin CNR in a separate and extended cohort. Furthermore, we present new data suggesting that a low CNR may predict outcome in tamoxife

Golfing with a murderer-Professional indifference and identity work in a Danish prison

Employees often use dis-identification strategies such as humor or cynicism to cope with emotional difficulties at work. In this paper, we show how dis-identification collapses among Danish correctional officers because of specific emotional contradictions arising from the 'dirty' aspects of their work. Correctional officers face the emotional dilemma of having to both get involved with the inmate

Studies of the pathogenesis of IgA nephropathy and Henoch-Schönlein purpura, with special reference to Streptococcus pyogenes infections and complement

Popular Abstract in Swedish IgA-nefropati (IgAN) är den vanligaste formen av primär inflammation av njurarna och Henoch-Schönlein purpura (HSP) den vanligaste formen av kärlinflammation i barndomen. HSP kan också drabba njurarna och kallas då Henoch-Schönlein nefropati (HSN). Orsaken till båda sjukdomar är inte helt klarlagd ännu. Båda kännetecknas av vävnadsinlagringar med immunoglobulin A (IgA)IgA nephropathy (IgAN) is the most common form of primary glomerulonephritis and Henoch-Schönlein purpura (HSP) the most common form of vasculitis in childhood. HSP may affect kidneys, a complication termed Henoch-Schönlein nephropathy (HSN). Renal pathology in HSN resembles that seen in IgAN. The pathogenesis of IgAN and HSP is so far unclear. Both are characterized by tissue deposits of undergly

Produced Consciousness: Shapes of the Machiavellian Snake

Consciousness, in the beginning of its scientific use, was considered to be material, i.e., to represent an attribute of substance or matter. During later periods, it was associated with learning processes. Based on questionnaires and interviews, a number of different definitions have made its learned content dependent on statistical measures of what people consciously know. However, statically an

Isospin symmetry in the odd-odd mirror nuclei (44)V/(44)Sc

Excited states in the N = Z - 2 nucleus (44)V have been observed for the first time. The states have been identified through particle-gamma-gamma coincidence relationships and comparison with analog states in themirror nucleus (44)Sc. Mirror energy differences have been extracted and compared to state-of-the-art shell-model calculations which include charge-symmetry-breaking forces. Observed decay

Perceptions of Trust and National Perspectives in Multinational Crisis Management: An Examination of the European Union Military Strategic Level

Popular Abstract in Swedish Förtroende och nationella perspektiv i multinationell krishantering: en studie av Europeiska Unionens militärstrategiska nivå Doktorsavhandling av Olof Ekman, avdelningen för Brandteknik och Riskhantering vid Lunds Tekniska Högskola (LTH), Lunds Universitet, försvarad den 9 december 2011. Tidigare forskning pekar på att förtroende i större kriser är viktigt för att saThis thesis is motivated by an increasing degree of unfamiliarity and prominence of national dimensions in multinational crisis management. The research rationale rests on the argument that trust is important but may erode when roles conflict, which in turn may result when stakeholder interests diverge. The thesis describes trust and national perspectives in terms of role conflict in an EU Operati

(68)Ga-labeled superparamagnetic iron oxide nanoparticles (SPIONs) for multi-modality PET/MR/Cherenkov luminescence imaging of sentinel lymph nodes.

The aim of this study was to develop (68)Ga-SPIONs for use as a single contrast agent for dynamic, quantitative and high resolution PET/MR imaging of Sentinel Lymph Node (SLN). In addition (68)Ga enables Cherenkov light emission which can be used for optical guidance during resection of SLN. SPIONs were labeled with (68)Ga in ammonium acetate buffer, pH 5.5. The labeling yield and stability in hum

Semiosis and the elusive final interpretant of understanding

While the conceptual history of the sign, as recounted by John Deely in Four ages of understanding, is immensely enlightening, history is never enough. If, before Augustine, it had occurred to no one that such diverse phenomena as are covered by this term had something in common, and if, in the time of Aquinas, Fonseca, and Poinsot, different usages of the term were in competition, the reason is n

Multiple Interactions, Saturation, and Final States in pp Collisions and DIS

In high energy collisions saturation and multiple collisions are most easily accounted for in transverse coordinate space, while analyses in momentum space have been more suitable for calculating properties of exclusive final states. In this paper I describe an extension of Mueller's dipole cascade model, which attempts to combine the good features of both these descriptions. Besides saturation it

A low-power 2nd-order CT delta-sigma modulator with an asynchronous SAR quantizer

This paper presents a low voltage continuous-time delta-sigma modulator (DSM) intended for the receiver of an ultra-low-power radio. The DSM features a 2nd-order loop filter implemented with a single operational amplifier to reduce the power consumption. Furthermore, a 4-bit quantizer is used to achieve high resolution while keeping the sampling frequency low. The quantizer is realized using the s

A polynomial multicommodity flow problem with difficult path generation

In the paper we consider a commonly known network design problem with demand restoration assuming stub release. No compact linear programming (LP) formulation for the problem is known, and all known non-compact LP formulations of the problem require NP-hard path generation (pricing). Therefore, the problem itself is suspected to be NP-hard - this, however, is not actually known. The main result of