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Dissociation between short-term increased graft survival and long-term functional improvements in Parkinsonian rats overexpressing glial cell line-derived neurotrophic factor.

The present study was designed to analyse whether continuous overexpression of glial cell line-derived neurotrophic factor (GDNF) in the striatum by a recombinant lentiviral vector can provide improved cell survival and additional long-term functional benefits after transplantation of fetal ventral mesencephalic cells in Parkinsonian rats. A four-site intrastriatal 6-hydroxydopamine lesion resulte

Combined use of hypothermia and buffering in the treatment of critical respiratory failure

A 20-year-old male, recovering from post-traumatic ARDS, subsequently developed pneumonia with extreme hypercapnia (PaCO2 max 19.4 kPa) and hypoxemia (PaO2 min 5.1 kPa), in spite of maximal mechanical ventilation. Hypothermia was induced by surface cooling, reducing the body temperature from 40 degrees C to a mean of 33.3 degrees C. Buffer infusion (1375 mmol) during the first 2 days increased bas

On controller & capacity allocation co-design for networked control systems

This paper presents a framework for examining joint optimal channel-capacity allocation and controller design for networked control systems using store-and-forward networks in a discrete-time linear time-invariant setting. The resultant framework provides a synthesis procedure for designing distributed linear control laws for capacity-constrained networks taking the allocation of the capacity with

Longing for unconsciousness

In the following paper, I intend to approach certain aspects of excessive, or heavy, drinking in the Middle East (and elsewhere) from a mainly psychological point of view. This psychological approach is meant to be complementary to the historical approach adopted in many of the other contributions to our conference. Having said this, I may perhaps be excused for referring to scholars and authors n

Chloride migration coefficient of self-compacting concrete

In this article laboratory and analytical studies of the chloride migration coefficient, D, are presented. The result of studies on chloride migration of Self-Compacting Concrete, SCC, are compared with the corresponding properties of normal concrete with the same water-cement ratio, w/c and air content. Both 28 and 90 days' age applied at the start of the testing. Six SCC were studied and 2 NC, a

Electric field effects in single semiconductor quantum dots observed by scanning tunneling luminescence

Scanning tunneling microscopy (STM) and scanning tunneling luminescence were used to correlate the topography with the emission spectra from individual self-assembled, InP quantum dots (QDs). We have investigated in detail how the electric field induced by the STM tip affects the emission from the QDs. This was done when exciting a QD, by altering the bias for constant current, by altering the cur

Infrared spectrum and bonding in uranium methylidene dihydride, CH2=UH2

Uranium atoms activate methane upon ultraviolet excitation to form the methyl uranium hydride CH3-UH, which undergoes alpha-H transfer to produce uranium methylidene dihydride, CH2UH2. This rearrangement most likely occurs on an excited-quintet potential-energy surface and is followed by relaxation in the argon matrix. These simple U + CH4 reaction products are identified through isotopic substitu

Performance evaluation of CDMA reverse links with imperfect beamforming in a multicell environment using a simplified beamforming model

Reverse link capacity of a direct-sequence code-division multiple-access (DS-CDMA) system in a multicell environment has been studied recently, and significant capacity improvements due to the use of beamforming have been observed. However, system performance with beamforming will be affected by several impairments, such as direction of arrival estimation errors, array perturbations, mutual coupli

Parents' worried state of mind when fetal ultrasound shows an unexpected finding: a comparative study.

OBJECTIVE: Most parents yearn for a second-trimester ultrasound examination and feel excitement about it, but some also worry about what the examination will show. According to prior research, using only generic instruments or specific questionnaires, anxiety decreases when the ultrasound findings are normal. The aim of this study was to compare parents' worry (Parents' Expectations, Experiences,

Stochastic modeling and simulation of traffic flow: asymmetric single exclusion process with Arrhenius look-ahead dynamics

A novel traffic flow model based on stochastic microscopic dynamics is introduced and analyzed. Vehicles advance based on the energy profile of their surrounding traffic implementing the "look-ahead" rule and following an underlying asymmetric exclusion process with Arrhenius spin-exchange dynamics. Monte Carlo simulations produce numerical solutions of the microscopic traffic model. Fluctuations

Molar mass and rheological characterisation of an exopolysaccharide from Pediococcus damnosus 2.6

The molar mass and theological properties of an exopolysaccharide (EPS) from Pediococcus damnosus 2.6 were investigated. The molar mass was determined by asymmetrical flow field-flow fractionation coupled with multiangle light scattering and refractive index detection. The EPS was observed to be a flexible chain polymer with a molar mass value of 4 x 10(6) g mol(-1). Heating the sample at 80 degre

Environmental monitoring using optical techniques

An overview of optical techniques for environmental monitoring is presented. Range-resolved measurements of atmospheric pollutants can be performed using the differential absorption lidar technique. Fluorescence lidar allows assessment of vegetation status and also the conditions of the facades of historical buildings. Diode lasers provide particularly realistic schemes for atmospheric gas analysi

Are digital images good enough? A comparative study of conventional film-screen vs digital radiographs on printed images of total hip replacement.

The aim of this study was to evaluate the inter- and intra-observer variability and to find differences in diagnostic safety between digital and analog technique in diagnostic zones around hip prostheses. In 80 patients who had had a total hip replacement (THR) for more than 2 years, a conventional image and a digital image were taken. Gruen's model of seven distinct regions of interest was used f

Late Holocene multi-proxy records of environmental change on the South Atlantic island Tristan da Cunha

Sediment stratigraphies from three sites, one lake, one overgrown lake, and an exposed section, on the island Tristan da Cunha in the temperate South Atlantic were analysed by means of pollen analysis, total carbon, nitrogen and sulphur content determination, magnetic susceptibility measurements and detailed radiocarbon dating. The aim of these studies was to reconstruct the late Holocene vegetati

Studies of resolidification of non-thermally molten InSb using time-resolved X-ray diffraction

We have used time-resolved X-ray diffraction to monitor the resolidification process of molten InSb. Melting was induced by an ultra-short laser pulse and the measurement conducted in a high-repetition-rate multishot experiment. The method gives direct information about the nature of the transient regrowth and permanently damaged layers. It does not rely on models based on surface reflectivity or

Loss of alpha 10 beta 1 integrin expression leads to moderate dysfunction of growth plate chondrocytes

Integrin alpha 10 beta 1 is a collagen-binding integrin expressed on chondrocytes. In order to unravel the role of the alpha 10 integrin during development, we generated mice carrying a constitutive deletion of the alpha 10 integrin gene. The mutant mice had a normal lifespan and were fertile but developed a growth retardation of the long bones. Analysis of the skeleton revealed defects in the gro

Improvement of the NEMO Potential by Inclusion of Intramolecular Polarization

The intermolecular electrostatic and induction energy of a NEMO potential which includes intramolecular polarization, are compared with a regular NEMO potential and a NEMO potential with configurationally dependent local properties. It is shown that the inclusion of intramolecular polarization improves the description of the intermolecular interactions when using the NEMO potential. (c) 2009 Wiley

Surface degradation of InxGa1-xN thin films by sputter-anneal processing: A scanning photoemission microscope study

The effects of nitrogen ion sputtering and thermal anneal processing on the surface electronic structure of the ternary III-V semiconductor In0.12Ga0.88N have been studied using scanning photoemission microscopy. No phase separation of the material is observed for annealing temperatures up to 650degreesC. However, samples annealed at 700degreesC for 5 h show clear evidence of phase separation. Fur

Memory in relation to depth of sedation in adult mechanically ventilated intensive care patients.

Objective: To investigate the relationship between memory and intensive care sedation. Design and setting: Prospective cohort study over 18 months in two general intensive care units (ICUs) in district university hospitals. Patients: 313 intubated mechanically ventilated adults admitted for more than 24 h, 250 of whom completed the study. Measurements: Patients (n = 250) were interviewed in the wa