The exact workings of amelogenin (AMG) as a key-regulator in the formation of enamel is still to be determined. It has been observed however, that AMG promotes tissue-regrowth and has promotive effect on e.g., osteoblastic cells and could therefore be of interest for medical applications. This project aimed to utilize AMG’s self-assembly properties to fabricate a protein-based biomaterial for cult

This paper presents an investigation that revolves around the Mexican writer Carlos Fuentes through three literary texts: Aura (1962), "Las dos Elenas" (Song of the Blind: 1964) and "La muñeca reina" (Song of the Blind: 1964). The concept under study is the double, a well-established phenomenon in literature, which often appears as a motive or theme in literary works. This essa

Breast reconstruction is a given choice for many women following mastectomy. There are a multitude of methods available today, and thus, comparative studies are essential to match patients with suitable methods. The aim of this study was to compare 5-year outcomes following delayed breast reconstruction with expander prosthesis (EP) and with deep inferior epigastric perforator (DIEP) flaps. Sevent

Aim To investigate temporal trends in primary care visits, physiotherapy visits, dispensed non-steroidal anti-inflammatory drugs (NSAIDs) and opioids in knee osteoarthritis (OA) patients who have and have not undergone knee replacement. Methods We analysed 5665 OA patients from the Skåne Healthcare Register, Sweden, who underwent knee replacement between 2015 and 2019. Controls were OA patients wi

Polyploidy and metastasis are associated with a low probability of disease-free survival in cancer patients. Polyploid cells are known to facilitate tumorigenesis. However, few data associate polyploidization with metastasis. Here, by generating and using diploid (2n) and tetraploid (4n) clones from malignant fibrous histiocytoma (MFH) and colon carcinoma (RKO), we demonstrate the migration and in

Background Interstitial lung abnormalities (ILA) are incidental findings on chest computed tomography (CT). These patterns can present at an early stage of fibrotic lung disease. Our aim was to estimate the prevalence of ILA in the Swedish population, in particular in never-smokers, and find out its association with demographics, comorbidities and symptoms. Methods Participants were recruited to t

The formation of metamorphic zircon after baddeleyite is a well-known reaction that can be used to date the metamorphism of igneous silica-undersaturated rocks. By contrast, metamorphic minerals formed after igneous zirconolite have rarely been reported. In this paper, we document metamorphic titanite + zircon pseudomorphs formed from the metamorphic breakdown of igneous zirconolite in syenodiorit

"Keltainen huone (Yellow Room)" recorded by 441 Hz Chamber Choir, conductor Anna Wilczewska in 2015 was released on a cd titled 'Modern Choral Masterpieces' in November 2015 on Dux Records (Poland).

The ability to learn new tasks and quickly adapt to different variations or dimensions is an important attribute in agile robotics. In our previous work, we have explored Behavior Trees and Motion Generators (BTMGs) as a robot arm policy representation to facilitate the learning and execution of assembly tasks. The current implementation of the BTMGs for a specific task may not be robust to the ch

A recent singleshot multiplane image (MPI) generation enables to copy an observed reality within a camera frame into other reality domains via view synthesis. While the scene scale is unknown due to the nature of singleshot MPI processing, camera tracking algorithms can estimate depth within the application world coordinate system. Given such depth information, we propose to adjust the scale of si

We present a geometric approach to portfolio theory with a focus on risk-adjusted returns, in particular Jensen’s alpha. We find that while the alpha/beta approach has severe limitations, especially in higher dimensions, only minor conceptual modifications (e.g., using orthogonal Sharpe ratios rather than risk-adjusted returns) are needed to identify the efficient trading strategies. We further sh

Temperature estimation plays a vital role across natural sciences. A standard approach is provided by probe thermometry, where a probe is brought into contact with the sample and examined after a certain amount of time has passed. In situations where, for example, preparation of the probe is non-trivial or total measurement time of the experiment is the main resource that must be optimized, contin

Objectives: To evaluate outcomes of management without surgical revascularization in patients with acute lower limb ischemia (ALI) in a population-based setting. Design: Retrospective observational population-based study. Materials: Patients from Malmö, Sweden, hospitalized for ALI between 2015 and 2018. Methods: In-hospital, surgical, radiological, and autopsy registries were scrutinized for desc

Brain cell structure and function reflect neurodevelopment, plasticity, and aging; and changes can help flag pathological processes such as neurodegeneration and neuroinflammation. Accurate and quantitative methods to noninvasively disentangle cellular structural features are needed and are a substantial focus of brain research. Diffusion-weighted MRS (dMRS) gives access to diffusion properties of

Recombinant adeno-associated viral vectors (rAAVs) have become an industry-standard technology in the field of gene therapy, but there are still challenges to be addressed in their biomanufacturing. One of the biggest challenges is the removal of capsid species other than that which contains the gene of interest. In this work, we develop a mechanistic model for the removal of empty capsids—those t

Here we present geomorphological evidence of a previously unrecognised ∼50 km long, ice-marginal moraine complex in southwestern Skåne, southernmost Sweden, which we name the “Lund Moraine”. This lobate moraine marks a sharp boundary between heavily streamlined and gently undulating landscapes, and closely outlines the extent of the “Lund till/diamicton”. We interpret that the moraine was formed b

Generating scientific advice to environmental management involves assessments with complex models, sparse data, and challenging empirical experiments, necessitating the integration of expert judgment with data into scientific models. To integrate expert judgement, assessors might elicit judgement by experts as quantiles, find a probability distribution that matches the quantiles, and add this info

We investigate a model for opinion dynamics, where individuals (modeled by vertices of a graph) hold certain abstract opinions. As time progresses, neighboring individuals interact with each other, and this interaction results in a realignment of opinions closer towards each other. This mechanism triggers formation of consensus among the individuals. Our main focus is on strong consensus (i.e., gl