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Impaired compensatory response to hypovolaemic circulatory stress in type 1 diabetes mellitus

Diabetes mellitus is associated with decreased haemodynamic stability and reduced tolerance to hypovolaemia. Compensatory haemodynamic responses during experimental hypovolaemia in type 1 diabetes patients with (DMR+) and without (DMR-) retinopathy as well as healthy controls (C) were studied. Lower body negative pressure created hypovolaemic circulatory stress. Volumetric techniques were used to

Cardiovascular response to acute hypovolemia in relation to age. Implications for orthostasis and hemorrhage

Venous compliance in the legs of aging man has been found to be reduced with decreased blood pooling (capacitance response) in dependent regions, and this might lead to misinterpretations of age-related changes in baroreceptor function during orthostasis. The hemodynamic response to hypovolemic circulatory stress was studied with the aid of lower-body negative pressure (LBNP) of 60 cmH(2)O in 33 h

Samhällsekonomi för socionomer

Boken ger grundläggande kunskape om samhällsekonomiska företeelser som påverkar socialpolitikens förutsättningar och finansieringen av välfärdsstaten, liksom det praktiska arbetet och människors möjligheter till försörjning. Den vänder sig primärt till socionomstudenter och verksamma inom socialt arbete, men även till studenter inom närliggande ämnen på universitet, högskolor och folkhögskolor.

Foreign Influences on Nordic (Noir) Borderlands

This article analyses the three recent Nordic Noir television series Bordertown (Sorjonen) from Finland, Trapped (Ófæro), from Iceland, and the Danish- Swedish The Bridge (Broen/Bron). All series are located on national borderlands, and this article aims to discern the significance of using such borderland settings. Departing from Doreen Massey's emphasis on places as being inherently interlinked

Energieffektiv utomhusbelysning längs gångvägar för människor med särskilda behov

Utomhusbelysning i offentliga miljöer har en viktig roll i en hållbar stadsutveckling. Energieffektiv LED-belysning kan stödja mobilitet i stadsmiljöer och medverka till en ökad tillgänglighet för personer med särskilda behov. Belysningen i föreliggande studie upplevdes ge tillräcklig ljusmängd och jämnt ljus, och det gick att se bra i belysningen. Trots att LED-belysningen ökade möjligheterna til

HLA associations in type 1 diabetes among patients not carrying high-risk DR3-DQ2 or DR4-DQ8 haplotypes

Type 1 diabetes is a complex disease where numerous genes are involved in the pathogenesis. Genes that account for approximately 50% of the familial clustering of the disease are located within or in the vicinity of the HLA complex on chromosome 6. Some DRB1, DQA1 and DQB1 genes are known to be involved, in addition to as yet unidentified HLA-linked genes. The DR4-DQ8 and DR3-DQ2 haplotypes are kn

Radioimmunoassay for glutamic acid decarboxylase-65.

BACKGROUND: Glutamic acid decarboxylase-65 (GAD65), the enzyme that catalyzes the formation of gamma-aminobutyric acid (GABA), is the major autoantigen in both type 1 (insulin-dependent) diabetes and stiff-man syndrome (SMS). The observation that GAD65 autoantibodies may be present for years before the clinical onset of diabetes raises the question of when GAD65 is available to initiate an immune

Islet autoantibodies in cord blood from children who developed type I (insulin-dependent) diabetes mellitus before 15 years of age

Islet autoantibodies are early markers for Type I (insulin-dependent) diabetes mellitus. The aim of this study was to establish whether islet autoantibodies were present at birth in children who developed Type I diabetes before 15 years of age. Cord blood sera from 81 children who developed Type I diabetes between 10 months and 14.9 years of age were tested for glutamic acid decarboxylase autoanti

Visual experience of brand-specific automobile design: Studying appreciation, emotion and comprehension using the VPE framework

This paper presents a qualitative questionnaire study of brand-specific visual product design in the automotive sector. The purpose of the study was to explore the visual product experience of automobile design as perceived by the general public and to analyse those experiences using an emerging framework for visual product experience; VPE. In the study; respondents were asked to assess the design