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In recent years there has been a growing interest among product development organizations to capitalize on engineering knowledge as their core competitive advantage for innovation. Capturing, storing, retrieval and sharing of engineering knowledge from a wide range of enterprise memory systems has become crucial part of knowledge management practice among competitive organizations. Managing and re

Statsmakterna kräver nu att verksamheterna vid Sveriges universitet och högskolor ska genomsyras av ett hållbarhetsperspektiv. Riksdagen har nu beslutat att dessa verksamheter ska ”främja en hållbar utveckling”. I regeringens Budgetproposition 2005/06:1 återfanns förslag till lag om ändring i högskolelagen. Där föreskrevs att 1 kap. 5 § högskolelagen (1992:1434) skall ha följande lydelse: Högskol

In order to qualify a subscriber loops for xDSL transmission, basic parameters like transfer function, scattering parameter S11 and characteristic impedance should be known. The aim of this paper is to present a test methodology for measurements of these basic parameters. The characteristic impedance is measured by open/short method and it is compared with the terminated measurement method defined

The hypothesis has been tested that evolution has resulted in lower thermal emissivity of eggs of birds breeding openly in cold climates than of eggs of birds that nest under protective covering or in warmer climates. Directional thermal emissivity has been estimated from directional–hemispherical reflectance spectra. Due to several methodological difficulties the absolute emissivity is not accura

Risk and vulnerability assessments (RVA) are vital components of the work conducted by public agencies at different levels, as part of the processes for governing and managing risks in the society. In Sweden, public agencies at all levels are required by legislation to perform risk and vulnerability assessments within their respective area of responsibility. The present paper presents a study of h

Background: An accurate medication list at hospital admission is essential for the evaluation and further treatment of patients. The objective of this study was to describe the frequency, type and predictors of errors in medication history, and to evaluate the extent to which standard care corrects these errors.Methods: A descriptive study was carried out in two medical wards in a Swedish hospital

Levosimendan is an inodilatory drug that mediates its cardiac effect by the calcium sensitization of contractile proteins. The target protein of levosimendan is cardiac troponin C (cTnC). In the current work, we have studied the interaction of levosimendan with Ca2+-saturated cTnC by heteronuclear NMR and small angle x-ray scattering. A specific interaction between levosimendan and the Ca2+-loaded

The catechol-O-methyltransferase (COMT) gene occurs as two polymorphic alleles, which code for a high activity thermostable and low activity thermolabile form of the enzyme. We devised a fast solid-phase minisequencing assay for genotyping the COMT gene at nucleotide position 544 encoding amino acid residue 158. The method was applied to correlate the genotype of the COMT gene with the biological

Phospholamban ablation is associated with significant increases in the sarcoplasmic reticulum Ca2+-ATPase activity and the basal cardiac contractile parameters. To determine whether the observed phenotype is due to loss of phospholamban alone or to accompanying compensatory mechanisms, hearts from phospholamban-deficient and age-matched wild-type mice were characterized in parallel. There were no

Bacillus stearothermophilus α-amylase has a signal peptide typical for proteins exported by Gram-positive bacteria. There is only one signal peptidase processing site when the protein is exported from the original host, but when it is exported by Escherichia coli, two alternative sites are utilized. Site-directed mutagenesis was used to study the processing in E. coli. Processing sites for 13 B. s

The binding of a new calcium sensitizer, levosimendan, to human cardiac troponin C (cTnC) is described. Fluorescence studies done on dansylated recombinant human cTnC and a site-directed mutant showed that levosimendan modulated the calcium-induced conformational change in cTnC, and revealed the role of Asp-88 in the binding of the drug to the NH2-terminal domain of cTnC. Furthermore, NMR studies

As the number of autonomous executive agencies increases, some countries have started merging agencies, thereby aiming to reduce fragmentation and cut public spending. These mergers have passed conspicuously unnoticed in research. In Sweden, the current wave of agency mergers started in the 1990ies. This paper aims to (1) give a background to the Swedish trajectory with agency mergers and to (2),

GLIT Learning Lund and Centre for Gender Studies Lund University, Sweden Sara.Goodman@genus.lu.se Abstract for Symposium Gender, IT and Learning, Helsingborg 23 -25 August 2007 This paper is a critical and personal reflection over developments in wide a dynamic research area - Gender, IT (ICT) and Learning. It aims to give a critical reflection on themes and issues that are the fields of study -