Sökresultat
Filtrera
Filtyp
Din sökning på "*" gav 534692 sökträffar
A projectome of the bumblebee central complex
Insects have evolved diverse and remarkable strategies for navigating in various ecologies all over the world. Regardless of species, insects share the presence of a group of morphologically conserved neuropils known collectively as the central complex (CX). The CX is a navigational center, involved in sensory integration and coordinated motor activity. Despite the fact that our understanding of n
High-Resolution Mapping of Ice Cover Changes in Over 33,000 Lakes Across the North Temperate Zone
More than 50% of global lakes periodically freeze, and their lake ice phenology is sensitive to climate change. However, spatially detailed quantification of the changes in lake ice at the global scale is not available. Here, we map ice cover in >33,000 lakes throughout the North Temperate Zone (23.5°–66.5°N) using 0.55 million Landsat images from 1985 to 2020. Over this period, we found a remarka
Understanding of photophysical processes in dio additive-treated ptb7:Pc71 bm solar cells
1,8-diiodooctane (DIO) additive is an important method for optimizing the morphology and device performance of polythieno[3,4-b]-thiophene-co-benzodithiophene (PTB7)-based polymer solar cells. However, the effect of DIO additive on charge photogeneration dynamics of PTB7-based polymer solar cells is still poorly understood. In this work, the effect of DIO additive on the carrier photogeneration dy
Semiotics, psychotherapy and Levinas’s ethics of “The Other”
The aim of this chapter is to show how insights from semiotics cancontribute to psychotherapy, notably the one inspired by Emmanuel Levinas’sethics of the other. Important to this undertaking are Augusto Ponzio’ssemiotic analyses of the ethics of Levinas. Moreover, a study of the Peirceannotion of abduction has proved to be fruitful in the further understanding ofhow psychotherapy can benefit from
A pragmatic defense of Millianism
A new kind of defense of the Millian theory of names is given, which explains intuitive counter-examples as depending on pragmatic effects of the relevant sentences, by direct application of Grice’s and Sperber and Wilson’s Relevance Theory and uncontroversial assumptions. I begin by arguing that synonyms are always intersubstitutable, despite Mates’ considerations, and then apply the method to na
Mitochondrial complex I and V gene polymorphisms associated with breast cancer in mizo-mongloid population
BackgroundMizoram has the highest incidence of cancer in India. Among women, breast cancer is most prevalent and the state occupies fifth position globally. The reason for high rate of cancer in this region is still not known but it may be related to ethnic/racial variations or lifestyle factors.MethodsThe present study aims to identify the candidate mitochondrial DNA (mtDNA) biomarkers—ND1and ATP
Reproductive and parental autonomy: : an argument for compulsory parental education
In this paper we argue that comprehensive and systematic parental education has the potential to equip young adults with the necessary information for the responsible exercise of their autonomy in choices about reproduction and parenting. Education can allow young adults to acquire largely accurate beliefs about reproduction and parenting and about the implications of their reproductive and parent
Total synthesis of (-)- and (+)-botryodiplodin and (+)- and (-)-epibotryodiplodin
Chiral Aldehydes by Ring Contraction of Pento- and Hexopyranoside Epoxides
The chiral aldehydes (-)-(2S,5S)- and (-)-(2S,5R)-2-[[[dimethyl( 1,1,2-trimethylpropyl)silyl]oxy]methyl]-5-methoxy-2,5-dihydrofuran-3-carbaldehyde (2 and 4) were synthesized in 60 and 15% yield, respectively, by lithium bromide induced rearrangement of 6-O-silylated methyl 2,3- and 3,4-anhydro-a- and -d-D-hexopyranosides, obtained in two steps from methyl α- and β-D-glucopyranoside. Rearrangement
Hyperglycaemia-associated Caspase-3 predicts diabetes and coronary artery disease events
BACKGROUND: Apoptosis is central in both diabetes and atherosclerosis, linked to pancreatic beta cell death and plaque progression. Circulating Caspase-3 has also been associated with diabetes and coronary calcium score. Here, we explored if soluble Caspase-3 (sCaspase-3) is associated with cardio-metabolic risk factors and predicts incidence of diabetes and coronary artery disease (CAD).METHODS:
"To be seen" - older adults and their relatives' care experiences given by a geriatric mobile team (GerMoT)
BACKGROUND: The proportion of older people in the population has increased globally and has thus become a challenge in health and social care. There is good evidence that care based on comprehensive geriatric assessment (CGA) is superior to the usual care found in acute hospital settings; however, the evidence is scarcer in community-dwelling older people. This study is a secondary outcome of a ra
TIGER : The gene expression regulatory variation landscape of human pancreatic islets
Genome-wide association studies (GWASs) identified hundreds of signals associated with type 2 diabetes (T2D). To gain insight into their underlying molecular mechanisms, we have created the translational human pancreatic islet genotype tissue-expression resource (TIGER), aggregating >500 human islet genomic datasets from five cohorts in the Horizon 2020 consortium T2DSystems. We impute genotypes u
Mapping institutional interventions to mitigate suicides : A study of causes and prevention
Suicide is an extreme, tragic act and an important subject for social inquiry. It is the rising public health issue prevalent in the Himalayan range of Pakistan. The young and educated population is more prone to suicide instead of using this prime phase of age productively. Unfortunately, the suicide problem remains unaddressed, the causes remain undefined, solutions are not in the works, and in
Patchy proteins, anions and the Hofmeister series
We investigate specific anion binding to a range of patchy protein models and use our results to probe protein-protein interactions for aqueous lysozyme solutions. Our molecular simulation studies show that the ion-protein interaction mechanism and strength largely depend on the nature of the interfacial amino acid residues. Via direct ion pairing, small anions interact with charged side-chains wh
Pathophysiology of type I (insulin-dependent) diabetes
20 Years of Nordic climate change crisis and tourism research : a review and future research agenda
Climate change poses an existential crisis for tourism and destinations. Nordic researchers have been at the forefront of research on climate change impacts, adaptation and mitigation. The review provides a brief account of some of the main themes in Nordic climate change research from a regional and international perspective and potential future research directions. Key themes identified include
Fast-tracking of single emitters in large volumes with nanometer precision
Multifocal plane microscopy allows for capturing images at different focal planes simultaneously. Using a proprietary prism which splits the emitted light into paths of different lengths, images at 8 different focal depths were obtained, covering a volume of 50x50x4 μm3. The position of single emitters was retrieved using a phasor-based approach across the different imaging planes, with better tha
Who chooses to enroll in a new national gambling self-exclusion system? A general population survey in Sweden
Background: Self-exclusion from gambling is a common method for prevention and harm reduction in hazardous gambling. However, few national self-exclusion programs, involving a large number of gambling operators and activities in a country, have been assessed scientifically. This study aimed to examine characteristics of individuals who chose to enroll in a recently introduced (January, 2019) natio