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Sammanfattning:Denna berättelse om immunoterapi kombinerad med ultrahypo-fraktionerad strålterapi har sitt ursprung i den kliniska studie som på engelska benämdes "Brain Immune Gene Tumour Therapy" (BRIGTT) som professor Leif G, Salford i Lund initierade strax innan 2000-millienium-skiftet. Ett specifikt tumörvaccin framställdes baserat på tumörceller som han extraherade ur tumörvävnad från den gl
In this study, a report is prepared on significantly low specific contact resistivity of alloyed and non-alloyed ohmic contacts fabricated on an as-grown n+-GaN layer and measured with the transfer length method. A low ρc = 8 × 10−8 Ω cm2 is extracted for the alloyed Ti/Al/Ni/Au, and ρc = 4 × 10−7 Ω cm2 for the unannealed Ti/Pd/Au. To achieve these, a highly doped n+-GaN layer with ND = 1.5 × 1019
Advancing the use of air-sensitive polar organometallic Grignard and organolithium reagents under more environmentally benign conditions, here we report the addition of these reagents to a-b unsaturated ketones and aldehydes using the deep eutetic solvent (DES) choline chloride (ChCl): glycerol (Gly) (1:2), under air. Reactions occur at room temperature within seconds with excellent regioselective
Introduction: The Swedish Sleep Apnea Registry (SESAR) collects clinical data from individual obstructive sleep apnea (OSA) patients since 2010. SESAR has recently been integrated with additional national healthcare data. The current analysis presents the SESAR structure and representative clinical data of a national sleep apnea cohort. Methods: Clinical data from unselected patients with a diagno
Flera stora byggprojekt pågår och planeras i Sverige, varav flera är skattefinansierade. Det ligger därför i både samhällets och byggbranschens parters intresse att utveckla kunskapen kring hur stora byggprojekt organiseras och leds, aktat de många samhällsförändringar som Sverige genomgått de senaste decennierna. Denna studie har följaktligen studerat hur olika samhällsförändringar påverkat förut
We show that a profinite group, in which the centralisers of non-trivial elements are metabelian, is either virtually pro-p or virtually soluble of derived length at most 4. We furthermore show that a prosoluble group, in which the centralisers of non-trivial elements are soluble of bounded derived length, is either soluble or virtually pro-p.
Generic statements play a crucial role in concept learning, communication and education. Despite many efforts, the semantics of generics remain a controversial issue, as they do not seem to fit our standard theories of meaning. In this article, we attempt to shed light on this problem by focusing on how these sentences function in reasoning. Drawing on a distinction between property and diagnostic
Inequality is ubiquitous in time and space. It is often measured simply as differences in incomes between various groups, but the phenomenon is more complex than so. Inequality is a many-faceted phenomenon that manifests itself in a number of ways. It shows up in a variety of contexts, for example gender, age, origin, ethnicity, disability, sexual orientation, class, religion and place. The presen
Traditional methods for measuring chemical exposure have challenges in terms of obtaining sufficient data; therefore, improved methods for better assessing occupational exposure are needed. One possible approach to mitigate these challenges is to use self-monitoring methods such as sensors, diaries, or biomarkers. In the present study, a self-monitored method for measuring soot exposure, which inc
Objective To elicit expert opinion and gain consensus on specific exercise intervention parameters to minimise hip bone mineral density (BMD) loss following traumatic lower limb amputation. Methods In three Delphi rounds, statements were presented to a panel of 13 experts from six countries. Experts were identified through publications or clinical expertise. Round 1 involved participants rating th
In a world where overlapping crises feel less like exceptions andmore like the new normal, the question of how to promoteresilience becomes central. ‘Interdisciplinary Perspectives on Resi-lience and the Welfare State’ examines how welfare state policiescan be adapted to provide sustainable support in times of ‚per-macrisis‘. With contributions from the fields of law, economics,political science,
För samverkansforumet Intelligent Intelligence, baserat på Lunds universitet, lämnades en rapport om de viktigaste forskningsresultaten från deltagande i International Association för Intelligence Educators årliga europeiska konferens.
We study stochastic interaction network models whereby a finite population of agents, identified with the nodes of a graph, update their states in response to pairwise interactions with their neighbors as well as spontaneous mutations. These include the main epidemic models, such as the Susceptible-Infected -Susceptible, the Susceptible-Infected-Recovered, and the Susceptible-Infected-Recovered-Su
Background Impulse control disorders (ICDs) are known psychiatric conditions in Parkinson’s disease (PD), especially as a side effect of antiparkinsonian therapy. Screening for vulnerable patients and avoiding high-risk treatments can be an effective approach to reduce the ICD burden in patients with PD. Thus, our goal was to identify risk factors for ICDs in PD in the Swedish total population. Me
We study perturbations of non-recurrent parameters in the exponential family. It is shown that the set of such parameters has Lebesgue measure zero. This particularly implies that the set of escaping parameters has Lebesgue measure zero, which complements a result of Qiu from 1994. Moreover, we show that non-recurrent parameters can be approximated by hyperbolic ones.
