During braking, both the rotor and pads experience wear, generating particles that may become airborne. In field tests, it is difficult to distinguish these particles from others in the surrounding environment, so it is preferable to use laboratory test stands to study the amount of airborne wear particles generated. The purpose of this work is to investigate the possibility of separate, capture,

Importance: Better understanding is needed of the degree to which individuals tolerate Alzheimer disease (AD)-like pathological tau with respect to brain structure (brain resilience) and cognition (cognitive resilience). Objective: To examine the demographic (age, sex, and educational level), genetic (APOE-ϵ4 status), and neuroimaging (white matter hyperintensities and cortical thickness) factors

Study Design: A nonblinded randomized controlled trial. Introduction: Occupation-based interventions are superior to physical exercise–based interventions in patients with activity limitations. However, only a few studies have examined the effect in patients with hand-related disorders. Patients recover heterogeneously, which could be due to personal factors, such as sense of coherence (SOC). Purp

We present a new type of wireless access infrastructure consisting of a fabric of dispersed electronic circuits and antennas that collectively function as a massive, distributed antenna array. We have chosen to name this new wireless infrastructure 'RadioWeaves' and anticipate they can be integrated into indoor and outdoor walls, furniture, and other objects, rendering them a natural part of the e

Secretory intestinal IgA can protect from re-infection with rotavirus (RV), but very little is known about the mechanisms that induce IgA production during intestinal virus infections. Classical dendritic cells (cDCs) in the intestine can facilitate both T cell-dependent and -independent secretory IgA. Here, we show that BATF3-dependent cDC1, but not cDC2, are critical for the optimal induction of

Objectives: Identification of biological markers that can guide treatment selection is considered to be a viable solution for personalized treatment for patients with psychiatric disorders. This study investigated whether macrophage migration inhibitory factor (MIF) levels at baseline were associated with mindfulness-based group therapy or cognitive behavioral therapy response in patients with mil

Airborne particulate matter emitted from motor vehicle brakes is a contributor to urban air quality. Therefore, a method to rank brake pairs (pads and rotors) with respect to their particle emission factors in a reliable way is needed to develop a low-emission disc brake. A novel inertial disc brake dynamometer designed for brake particle emission studies, a modified SAE J 2707 cycle, an electrica

Supermassive black holes are found in most galactic nuclei. A large fraction of these nuclei also contain a nuclear stellar cluster surrounding the black hole. Here we consider the idea that the nuclear stellar cluster formed first and that the supermassive black hole grew later. In particular we consider the merger of three stellar clusters to form a nuclear stellar cluster, where some of these c

The pathophysiology of Parkinson's disease, dementia with Lewy bodies, multiple system atrophy, and many others converge at alpha-synuclein (α-Syn) aggregation. Although it is still not entirely clear what precise biophysical processes act as triggers, cumulative evidence points towards a crucial role for protein quality control (PQC) systems in modulating α-Syn aggregation and toxicity. These enc

A key challenge in X-ray crystallography is to find a good point on the crystal on which to center the beam because the crystal takes radiation damage after a number of shots which significantly distort the measurements. Therefore, the beam needs to be aimed manually by an operator, which results in significant additional effort and time.This paper presents an approach toward automating the beam a

Aim: Kynurenine metabolites are potential modulators of psychiatric disease. We aimed to develop a highly sensitive biochemical analysis of cerebrospinal fluid (CSF) tryptophan (TRP) metabolites, to investigate the stability of metabolites and to confirm our previous findings of aberrant CSF quinolinic acid (QUIN) and picolinic acid (PIC) in suicide attempters using this method. Methodology &

The effects of diversity in management teams on firm innovation have become an important topic in strategic management. With a few exceptions, however, the literature has focused on diversity in top management teams (TMTs), while the role of diversity in lower management levels, particularly middle management teams (MMTs), has usually been neglected. In this paper, we intend to fill this gap by ex

This article uses a socio-legal perspective to analyse the use of ethics guidelines as governance tool in the development and use of artificial intelligence (AI). This has become a central policy area in several large jurisdictions, including China and Japan, as well as the EU, focused here. Particular emphasis is in this article placed on the Ethics Guidelines for Trustworthy AI published by the

Environmental considerations, concerning the negative impacts of ship exhaust gases and particles on ambient air quality, are behind the requirements of cleaner marine fuels currently applied in designated emission control areas (ECAs). We investigated the impact of a ship operating on two types of fuel on the indoor air quality onboard. Gaseous and particulate air pollutants were measured in the

We have studied the dissociation of the trifluoromethane molecule, CHF3, into negative ionic fragments at the C 1s and F 1s edges. The measurements were performed by detecting coincidences between negative and positive ions. We observed five different negative ions: F−, H−, C−, CF−, and F2 −. Their production was confirmed by the analysis of triple coincidence events (negative-ion/positive-ion/pos

The recent Regulation (EU) 2019/1381, published on the 6th September 2019, aims to improve the transparency and sustainability of the EU risk assessment in the food chain by amending the General Food Law Regulation (EC 178/2002) and a number of other regulations related to the food sector. This Regulation is introduced as a response to the Fitness Check of the General Food Law Regulation as well a

This article analyzes communication practitioners’ accounts to interpret what power effects the strategy discourse has on their “way of seeing” themselves and their work. Through an analysis of 26 interviews with communication practitioners, the findings show that strategy, understood as a discursive body of knowledge, has empowered practitioners by enabling them to produce an understanding of the

Cu is required to be abated in brake pads due to its toxicity. There are on the market several Cu-free brake pads. These Cu-free brake pads are only evaluated regarding their friction and wear performance, whereas, their airborne particle emissions are not considered. A pin-on-disc tribometer is used to evaluate the friction, wear and airborne particle emission from two Cu-free commercial brake pa

Most modern passenger cars have disc brakes on the front wheels. Unlike drum brakes, disc brakes are not sealed off from the ambient air. During braking, both the rotor and the pads wear, and this wear process generates particles that may become airborne. In field tests it is difficult to distinguish these particles from others in the environment. It is thus preferable to conduct tests using labor