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Distinct Serotypes of Streptococcal M Proteins Mediate Fibrinogen-Dependent Platelet Activation and Proinflammatory Effects

Sepsis is a life-threatening complication of infection that is characterised by a dysregulated inflammatory state and disturbed hemostasis. Platelets are the main regulators of hemostasis, and they also respond to inflammation. The human pathogen Streptococcus pyogenes can cause local infection that may progress to sepsis. There are more than 200 different serotypes of S. pyogenes defined accordin

Water assessment in transboundary river basins : the case of the Medjerda River Basin

Water resources in the Middle East and North Africa (MENA region) face over-exploitation and over-pollution due to population growth, climate change and the lack of advanced water governance approaches. These challenges become more serious in transboundary river basins and may lead to conflict between riparian countries. The main objective of this paper is to assess water resources and needs at th

Assessing combined object and mutual shading on the performance of a solar field

To make well-informed decisions on the implementation of solar energy on roofs within the urban environment, a new method was developed and described that could support such decision-making. This method takes both the mutual shading and shading from external objects into account. The method consists of the following six steps: 1) construction of the scene, 2) performance of annual solar irradiatio

Tools and methods for solar building design : Results of IEA Task 41 international survey

As part of the IEA-SHC Task 41 'Solar Energy and Architecture' an international survey was carried out. This paper presents its results for Subtask B which especially focuses on methods and tools for solar design applied by architects. Building professionals, mainly architects, were contacted via email and asked to participate in a web-based questionnaire about their use of methods and tools for s

Efficient reversible CO/CO2 conversion in solid oxide cells with a phase-transformed fuel electrode

The reversible solid oxide cell (RSOC) is an attractive technology to mutually convert power and chemicals at elevated temperatures. However, its development has been hindered mainly due to the absence of a highly active and durable fuel electrode. Here, we report a phase-transformed CoFe-Sr3Fe1.25Mo0.75O7−δ (CoFe-SFM) fuel electrode consisting of CoFe nanoparticles and Ruddlesden-Popper-layered S

Solar Energy in the Nordic Built Environment: Challenges, Opportunities and Barriers

Within the framework Solar Heating and Cooling Programme of the International Energy Agency Task 51 “Solar Energy in Urban Planning”, case studies from Norway, Sweden, and Denmark were collected and analyzed through a comparative approach. The cases were first classified based on their urban characterization (existing and new urban areas) and then compared within the same country or in a cross-cou

Potential antidiabetic phytochemicals in plant roots : a review of in vivo studies

Background: Medicinal plants are used to treat various disorders, including diabetes, globally in a range of formulations. While attention has mainly been on the aerial plant parts, there are only a few review studies to date that are focused on the natural constituents present in the plant roots with health benefits. Thus, the present study was performed to review in vivo studies investigating th

Causal Cognition and Theory of Mind in Evolutionary Cognitive Archaeology

It is widely thought that causal cognition underpins technical reasoning. Here we suggest that understanding causal cognition as a thinking system that includes theory of mind (i.e., social cognition) can be a productive theoretical tool for the field of evolutionary cognitive archaeology. With this contribution, we expand on an earlier model that distinguishes seven grades of causal cognition, ex

The Long-Term Impact of Levodopa/Carbidopa Intestinal Gel on ‘Off’-time in Patients with Advanced Parkinson’s Disease : A Systematic Review

Introduction: Levodopa/carbidopa intestinal gel (LCIG; carbidopa/levodopa enteral suspension) has been widely used and studied for the treatment of motor fluctuations in levodopa-responsive patients with advanced Parkinson’s disease (PD) when other treatments have not given satisfactory results. Reduction in ‘off’-time is a common primary endpoint in studies of LCIG, and it is important to assess

Editor's Choice – Outcome of Radical Surgical Treatment of Abdominal Aortic Graft and Endograft Infections Comparing Extra-anatomic Bypass with In Situ Reconstruction : A Nationwide Multicentre Study

Objective: Abdominal aortic graft and endograft infection (AGI) is primarily treated by resection of the infected graft and restoration of distal perfusion through extra-anatomic bypass (EAB) or in situ reconstruction/repair (ISR). The aim of this study was to compare these surgical strategies in a nationwide multicentre retrospective cohort study. Methods: The Swedish Vascular Registry (Swedvasc)

The effect of education on poverty : A European perspective

More than 1 in 7 people in Europe live in a household whose income is below the national poverty line, but more than 30% of people consider themselves to live in poverty. This study provides evidence on the causal relationship between education and various dimensions of poverty. I construct a novel database comprising compulsory schooling reforms in 32 European countries and use them as instrument

Impacts of climate change and anthropogenic activities on vegetation change : Evidence from typical areas in China

Understanding the interactions of climate-vegetation and human-vegetation has been a critical issue and increasingly attracting attention from scientific community in the field of global change research. This study investigated the heterogeneous impacts of climate change and anthropogenic activities on vegetation change by applying the trend analysis and Geodetector approach. The spatial and tempo

Excited-state properties of Y-series small molecule semiconductors

The emergence of the Y series small molecule semiconductors, Y6 and its derivatives, have significantly improved the performance of polymer solar cells (PSCs). However, the excited-state properties of these Y-series small molecule semiconductors which are highly important for designing high-performance PSCs, need to be illustrated. In this work, the excited-state properties and electronic structur

Attitudes of food consumers at universities towards recycling human urine as crop fertiliser : A multinational survey dataset

We present here a data set generated from a multinational survey on opinions of university community members on the prospect of consuming food grown with human urine as fertiliser and about their urine recycling perceptions in general. The data set comprises answers from 3,763 university community members (students, faculty/researchers, and staff) from 20 universities in 16 countries and includes

Association of phthalate exposure with thyroid function during pregnancy

Background: The extent of thyroid disruptive effects of phthalates during pregnancy remains unclear. Aim: To investigate the association of maternal urinary phthalates with markers of the thyroid system during early pregnancy. Methods: Urinary concentrations of phthalate metabolites and serum concentrations of thyroid stimulating hormone (TSH), free and total thyroxine (FT4 and TT4) and free and t