Heterotopic ossification (HO) in tendons can lead to increased pain and poor tendon function. Although it is believed to share some characteristics with bone, the structural and elemental compositions of HO deposits have not been fully elucidated. This study utilizes a multimodal and multiscale approach for structural and elemental characterization of HO deposits in healing rat Achilles tendons at

Horse liver alcohol dehydrogenase was immobilized on glycerylpropyl-silica (10 μm, 1000-Å pores) activated with 2,2,2-trifluoroethanesulfonyl chloride (tresyl chloride). The coupling and activity yield was almost 100%. The coenzyme-binding sites were equivalent and virtually unaffected by the immobilization process, as judged from Scatchard plots and active-site titrations. The silica-bound enzyme

Lactate dehydrogenase has been purified by precipitation with a bis-ligand. The precipitating agent in this case was Bis-NAD. This approach of affinity precipitation is also applicable to other enzymes.

Magnetic calcium alginate yeast beads, made by incorporation of magnetite or colloidal magnetic liquid, FerrofluidTM, exhibited catalytic behavior similar to that of their nonmagnetic counterparts. The magnetic immobilized preparations’ shortterm performance, long-term operational stability, and capacity forin situ activation were unaffected by the inclusion of magnetic material. The magnetic qual

Concanavalin A was covalently bound to porous silica (100-1000 Å) by three different coupling procedures. The performance of the preparations was evaluated from their ability to resolve a mixture of closely related sugars. The Concanavalin A-silica was used for efficient and rapid (5-20 min) analysis/purification of samples containing the glucoproteins peroxidase and glucose oxidase. Such columns

Three methods were developed for preparing alginate gels containing cells that are stable in phosphate containing media. In Method I preformed alginate beads containing entrapped cells were treated with polyethyl eneimine followed by glutaraldehyde. In Method II alginate sol was treated with a carbodiimide and N-hydroxysuccinimide (to form active esters), mixed with cells and extruded into calcium

The reactive triazine dye, Cibacron Blue F3G-A, has been covalently attached to microparticulate porous silica and used for the resolution of a number of complementary proteins by high-performance liquid affinity chromatography (HPLAC). Cibacron Blue F3G-A was converted to its 6-aminohexyl derivative by reaction with 1,6-diaminohexane and coupled to γ-glycidoxypropyltrimethoxysilane-activated poro

An enzyme-coenzyme complex was immobilized on the surface of a glassy carbon electrode and investigated with cyclic voltammetry in ethanol-containing buffers. The complex consists of an Liver Alcohol Dehydrogenase molecule to which an NAD-analogue is covalently attached via its straight six-carbon, spacer. One cycle was observed but repeated recycling could not be carried out. presumably due to ca

Since the incorporation of the UN Convention on the Rights of the Child into Swedish legislation on January 1, 2020, the topic of children’s rights and the best interests of the child has gained increased prominence within social services – not least within the context of financial assistance. We have conducted interviews with eight social workers in a Swedish municipality to examine how work rela

Degrowth seeks to achieve a sustainable society in the future. It implies overcoming capitalist norms and structures. Economic organizations have found little attention in degrowth scholarship. The existing literature focuses on degrowth compatibility without the wider structural and societal consideration that degrowth implies. Further, it is riddled with incoherences, such as a supposed compatib

OBJECTIVE: This study aimed to evaluate the effect of orthognathic surgery on quality of life among Swedish patients.MATERIALS AND METHODS: Patients subjected to orthognathic surgery due to dentofacial deformity (DFD) and registered in the National Register of Orthognathic Surgery (NROK) in Sweden between 2017 and 2020 were eligible for inclusion in this study. The Swedish-validated Orthognathic Q

Genome-wide association studies (GWASs) based on common single nucleotide polymorphisms (SNPs) have identified several loci associated with the risk of monoclonal gammopathy of unknown significance (MGUS), a precursor condition for multiple myeloma (MM). We hypothesized that analyzing haplotypes might be more useful than analyzing individual SNPs, as it could identify functional chromosomal units

BACKGROUND: Tuberous sclerosis complex (TSC) is a rare multisystem autosomal dominant disorder caused by pathogenic variants in either the TSC1 or TSC2 gene. Common manifestations of TSC have been grouped into major and minor clinical diagnostic criteria and assessed in clinical routine workup. However, case studies point towards the existence of rare disease manifestations and to the potential as

The present article investigates key dilemmas in collective legal mobilization initiatives in the field of asylum and migrants’ rights. Focusing on my own experiences from working in the Asylum Commission – a trans-sectional mobilization initiative that ran in Sweden from 2019 to 2022, involving researchers, civil society representatives, and professionals – I analyze two central dilemmas that cha

During the last few years Europe has made enormous progress towards free electron laser (FEL)-based research infrastructures. The FLASH facility [1] at DESY in Hamburg, Germany, has been in user operation since the summer of 2005; FERMI@Elettra [2] in Trieste, Italy, is under construction; the European XFEL [3] in Hamburg will start construction in summer 2008; and several other FEL projects are b

Objectives: To report the long-term outcomes from a longitudinal psychosocial study that forms part of the ‘Identification of Men with a genetic predisposition to ProstAte Cancer: Targeted Screening in men at higher genetic risk and controls’ (IMPACT) study. The IMPACT study is a multi-national study of targeted prostate cancer (PrCa) screening in individuals with a known germline pathogenic varia

An overview of the European storage ring free electron laser (FEL) project was presented. The details of initial lasing at 350 nm and 220 nm ranges were also presented. The distinguising features of the project were the use of an optical klystron to reduce power loading on the mirrors, the use of sophisticated mirror chambers and the integration of the FEL on a low emittance synchrotron radiation

The MAX-IV linac will be used both for injection and top up into two storage rings, and as a high brightness injector for a Short Pulse Facility (SPF) and an FEL (in phase 2). 100 pC bunches of electrons are created from a 1.5 cell $-band photocathode gun and subsequently accelerated up to 3 GeV by $-band linac sections. Simulations of the dynamics of the space-charge dominated beam up to 100 MeV