PRECLINICAL DRUG DISCOVERY AND DEVELOPMENT FOR A NOVEL ALZHEIMER’S DISEASE DRUG : - A stroy of an orphan -
Alzheimer’s disease is a severe neurodegenerative disease, affecting the life of millions of patients and those who stand close to them. There is an urgent need for new effective medical treatments targeting this disease, as up to now, there is none. GPR3, a highly constitutively active orphan G protein coupled receptor, was found to interact with several different molecules that are known to play