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Simultaneous PLIF Imaging of OH and PLII Imaging of Soot for Studying the Late-Cycle Soot Oxidation in an Optical Heavy-Duty Diesel Engine

The effects of injection pressure and swirl ratio on the in-cylinder soot oxidation are studied using simultaneous PLIF imaging of OH and LII imaging of soot in an optical diesel engine. Images are acquired after the end of injection in the recirculation zone between two adjacent diesel jets. Scalars are extracted from the images and compared with trends in engine-out soot emissions. The soot emis

Stapling in thyroid surgery. A prospective study

In a prospective study, resection of the thyroid gland by means of a linear stapling device was compared with the conventional resection technique in 12 consecutive patients with thyreotoxicosis. The median time for resection of the stapled lobe was shorter than for the conventionally resected right lobe, although the difference was not statistically significant. The median preoperative bleeding d

Risk factors for postoperative hypocalcemia after surgery for primary hyperparathyroidism

HYPOTHESIS: A variety of clinical and biochemical variables may be associated with hypocalcemia after surgery for parathyroid adenoma.DESIGN: A prospective study of patients who underwent surgery for solitary parathyroid adenoma.SETTING: A university hospital department of surgery.PATIENTS: Eighty-six consecutive patients who underwent surgery for solitary parathyroid adenoma.INTERVENTION: Parathy

ISA-2011B, a phosphatidylinositol 4-phosphate 5-kinase a inhibitor, impairs CD28-dependent costimulatory and pro-inflammatory signals in human T lymphocytes

Phosphatidylinositol 4,5-biphosphate (PIP2) is a membrane phospholipid that controls the activity of several proteins regulating cytoskeleton reorganization, cytokine gene expression, T cell survival, proliferation, and differentiation. Phosphatidylinositol 4-phosphate 5-kinases (PIP5Ks) are the main enzymes involved in PIP2 biosynthesis by phosphorylating phosphatidylinositol 4-monophosphate (PI4

Prognostic value of HER3 and HER2 alterations in colorectal cancer: Relationship with sidedness, KRAS and BRAF mutation status

Background Human epidermal growth factors 2 and 3 (HER2 and HER3) are members of the EGFR family that drives oncogenesis mainly through activation of the RAS-RAF-MEK-ERK pathway. While the prognostic value of HER2 and HER3 alterations in colorectal cancer (CRC) remains uncertain, KRAS and BRAF mutations confer resistance to targeted therapies and poor prognosis. Sidedness of the primary tumour has

Long-term follow-up of patients with ANCA-associated vasculitis

Bibliographical note: Här klistrar du in följande text:Defence detailsDate: [yyyy-mm-dd]Time: [hh:mm]Place: [text without newline or tabs]External reviewer(s)Name: [surname, first name]Title: [text without newline or tabs]Affiliation: [text without newline or tabs]---ISSN: 1652-8220Lund University, Faculty of Medicine Doctoral Dissertation Series 2017:??This thesis is based on long-term follow-up results from two cohorts of patients with ANCA-associated vasculitis; one cohort with 535 patients originally included in 4 European randomized clinical trials (papers I and II) and one Swedish population-based cohort including 195 patients (papers III and IV). Two areas are covered in the two cohorts, respectively; the assessment of mortality, prognosti

Cubosomes post-loaded with antimicrobial peptides : Characterization, bactericidal effect and proteolytic stability

Novel antibiotics, such as antimicrobial peptides (AMPs), have recently attended more and more attraction. In this work, dispersed cubic liquid crystalline gel (cubosomes) was used as drug delivery vehicles for three AMPs (AP114, DPK-060 and LL-37). Association of peptides onto cubosomes was studied at two cubosome/peptide ratios using high performance liquid chromatography, ζ-potential and circul

Assessing the adaptive capacity of multi-level water governance : ecosystem services under climate change in Mälardalen region, Sweden

Adaptive and multi-level governance is often called for in order to improve the management of complex issues such as the provision of natural resources and ecosystem services. In this case study, we analyse the contemporary multi-level governance system that manages water resources and its ecosystem services in a fresh water lake in Sweden. We assess the relative importance and barriers of three c

Why small states join big wars: the case of Sweden in Afghanistan 2002-2014

The security behavior of small states has traditionally been explained by different takes of realism, liberalism, or constructivism – focusing on the behavior that aims toward safeguarding sovereignty or engaging in peace policies. The issue of why states with limited military capacities and little or no military alignments or engagements decide to participate in an international mission has recei

The Financial Revolution in Sweden, 1650 – 1900

This chapters looks at the Swedish financial revolution in a long-term perspective. It begins with the establishment of the first formal financial organization, the Stockholm Banco in 1656, and follows the financial development until the end of the nineteenth century. The development of each part of the financial system is described in relation to the financial, economic, and political development

The unifying force of humor: on self-directed ethnic humor and the dedramatization of ethnicity

Drawing on an ethnographic fieldwork within the hotel and restaurant industry in a multiethnic workplace in Denmark, this paper draws attention to the informal social interaction between first-generation immigrants and native Danish co-workers. Elaborating on life oriented cultural concepts of cultural sociologybased on Erving Goffman, the paper explores immigrants’ use of so-called self-directed

A global synthesis of the effects of diversified farming systems on arthropod diversity within fields and across agricultural landscapes

Agricultural intensification is a leading cause of global biodiversity loss, which can reduce the provisioning of ecosystem services in managed ecosystems. Organic farming and plant diversification are farm management schemes that may mitigate potential ecological harm by increasing species richness and boosting related ecosystem services to agroecosystems. What remains unclear is the extent to wh

Biological predictors of insulin resistance associated with posttraumatic stress disorder in young military veterans

Posttraumatic stress disorder (PTSD) is associated with increased risk for Type 2 diabetes and cardiovascular disease (cardiometabolic disease), warranting research into targeted prevention strategies. In the present case–control study of 160 young (mean age 32.7 years) male military veterans, we aimed to assess whether PTSD status predicted increased markers of cardiometabolic risk in otherwise h

Psychological factors influencing restrained behaviors during armed conflicts – A review of findings and challenges

Severe unrestrained behaviors during armed conflicts, such as the massacre in My Lai or abusive transgressions such as the torture-like behaviors occurring in Abu-Ghraib prison, often lead to increased difficulties to decrease hostilities or to gain a peaceful ending to a military conflict. Therefore, it is of highest relevance to understand which individual, situational and organizational factors