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Boreal forests and peatlands are globally significant carbon stores but they are threatened by rising air temperatures and changes in precipitation regimes and the frequency of natural disturbances. Predicting how the boreal biome will respond to climate change depends on being able to accurately model and upscale the greenhouse gas fluxes between these ecosystems and the atmosphere. This thesis f

Oxygen and nitrate availabilities impact the marine nitrogen cycle at a range of spatial and temporal scales. Here, we demonstrate the impact of denitrifying foraminifera on the nitrogen cycle at two oxygen and nitrate contrasting stations in a fjord environment (Gullmar Fjord, Sweden). Denitrification by benthic foraminifera was determined through the combination of specific density counting per

Public policy has a critical role to play in supporting business actors towards their transition to more sustainable and less resource‐intensive practices within the context of a Circular Economy (CE). The European Union (EU) CE Action Plan sets a special focus on the role of business in adopting and promoting circular economic principles in their operations, and thus leading the transition toward

Background: Infection and graft-versus-host disease (GvHD) are the major causes for mortality and morbidity of allogeneic hematopoietic stem cell transplantation (allo-HSCT). Plasma-derived extracellular vesicles (EVs) contain disease-related proteins, DNAs and RNAs, and have recently been suggested as potential biomarker candidates for transplantation complications. However, EV isolation from sma

Synaptic pathology is a central event in Alzheimer’s disease (AD) and other neurodegenerative conditions, and investigation of synaptic proteins can provide valuable tools to follow synaptic dysfunction and loss in these diseases. Neuroligin-1 (Nlgn1) is a postsynaptic cell adhesion protein, important for synapse stabilization and formation. Nlgn1 has been connected to cognitive disorders, and spe

In the present work, the laminar burning velocities of the NH3+N2O+air flames were measured using the heat flux method at 1 atm and 298 K, with varied equivalence ratios and N2O mixing ratios. For the mixing ratio N2O/(N2O+air) = 0.5, a full range of equivalence ratios was covered. Moreover, at three equivalence ratios an extended range of mixing ratios was investigated. The laminar burning veloci

Infantile malignant osteopetrosis is a devastating disorder of early childhood that is frequently fatal and for which there are only limited therapeutic options. Gene therapy utilizing autologous hematopoietic stem and progenitor cells represents a potentially advantageous therapeutic alternative for this multisystemic disease. Gene therapy can be performed relatively rapidly following diagnosis,

A recent literature emphasizes that gender differences in the labor market may in part be driven by a gender gap in willingness to compete. However, whereas experiments in this literature typically investigate willingness to compete in private environments, real world competitions often have a more public nature, which introduces potential social image concerns. If such image concerns are importan

(1) Background: Although several neighborhood environmental factors have been identified to be associated with older adults’ physical activity, little research has been done in rural areas where the population is aging. This study aimed to investigate neighborhood environmental factors and the longitudinal change of physical activity status among rural older adults in Japan. (2) Meth-ods: The stud

We introduce a new method to mitigate numerical diffusion in adaptive mesh refinement (AMR) simulations of cosmological galaxy formation, and study its impact on a simulated dwarf galaxy as part of the 'EDGE' project. The target galaxy has a maximum circular velocity of 21 km s-1 but evolves in a region that is moving at up to 90 km s-1 relative to the hydrodynamic grid. In the absence of any miti

BACKGROUND: A hydraulic force generated by blood moving the atrio-ventricular plane is a novel mechanism of diastolic function. The direction and magnitude of the force is dependent on the geometrical relationship between the left atrium and ventricle and is measured as the short-axis atrio-ventricular area difference (AVAD). In short, the net hydraulic force acts from a larger area towards a smal

Is the oncogene MYC upregulated or hyperactive? In the majority of human cancers, finding agents that target c-MYC has proved difficult. Here we report specific bacterial effector molecules that inhibit cellular MYC (c-MYC) in human cells. We show that uropathogenic Escherichia coli (UPEC) degrade the c-MYC protein and attenuate MYC expression in both human cells and animal tissues. c-MYC protein

This paper examines the association between daytime electric lighting use and perceived indoor daylight availability in residential spaces. In addition, occupant preferences were evaluated, in particular which rooms are prioritized in terms of daylight availability. The study deployed a questionnaire survey that was carried out in typical multi-dwelling apartment blocks in Malmö, Sweden (Latitude:

In prospective observational cohort studies, increasing sun exposure habits have been associated with reduced risk of cardiovascular mortality. Our aim was to assess possible observational mechanisms for this phenomenon. A written questionnaire was answered by 23,593 women in the year 2000 regarding risk factors for melanoma, including factors of possible interest for hypertension, such as detaile