The aim of this report was to review the literature to identify existing best practices used to prevent incursions into work zones and improve safety of road users and road workers. A systematic literature search was conducted and various available sources referred to by knowledgeable experts in the field were considered. Best practices found in the literature review comprise both regulatory/manag

Aims: Drug development for paediatric pulmonary arterial hypertension (PAH) ispressingly needed. Experts from the US Food and Drug Administration, EuropeanMedicines Agency, Health Canada, key opinion leaders, academia, patients, and industry representatives held a workshop on 12th June 2017 dedicated to addressing challenges and unmet needs. This report summarises the approaches proposed during th

While it is understood that cities generate the majority of carbon emissions, for most cities, towns, and rural areas around the world no carbon footprint (CF) has been estimated. The Gridded Global Model of City Footprints (GGMCF) presented here downscales national CFs into a 250 m gridded model using data on population, purchasing power, and existing subnational CF studies from the US, China, EU

Fishing access agreements have been widely criticized but there is little quantitative evidence of their effects on the economies of developing countries. The aim of this paper is to investigate the influence of the European Union’s fishing access agreements on 15 African countries’ fish exports to the OECD. More specifically, we investigate the effects on the extensive and intensive margins of tr

The presence of contralateral tactile input can profoundly affect ipsilateral tactile perception, and unilateral stroke in somatosensory areas can result in bilateral tactile deficits, suggesting that bilateral tactile integration is an important part of brain function. Although previous studies have shown that bilateral tactile inputs exist and that there are neural interactions between inputs fr

Utgör lokala eliter i Sverige välintegrerade sociala enheter, eller återfinns de i flera socialt åtskilda elitfraktioner? Är kvinnor inom den lokala eliten inte bara underrepresenterade till antal, utan även strukturellt missgynnade på grund av sitt kön? Och i vilken mån bidrar elitpersonernas informella umgänge, i till exempel Rotary-klubbar, till deras övergripande integration och sociala kapitaThe study applies network analysis to empirically study the integration of local elites in four Swedish municipalities. We focus particularly on the existence of elite fractions, the structural representation of women, and the role of informal ties for integration.

This study analyzes the demographics, criminality, and network relations of forty-one deceased Swedish foreign fighters. Our results show that most of the deceased Swedish foreign fighters were on average just under 26 years old when they died. Concerning network relations, nineteen out of the forty-one foreign fighters had at least one relationship (next-of-kin or friend) with another deceased fo

The properties of combined multiplier and penalty function methods are investigated using a second-order expansion and results known for the Riccati equation. It is shown that the lower bound of the values of the penalty constant necessary to obtain a minimum is given by a certain Riccati equation. The convergence rate of a common updating rule for the multipliers is shown to be linear.

This article deals with some Yemeni events that affect the policy, and the other social aspects. A Yemeni singer made a concert with Yemeni Israeli singer, however, this event caused a lot of reaction in the social media, the article attempts to discuss these reactions.

This chapter summarizes the proteomic tools and strategies used in asthma research. It provides a background to the remodeling process occurring in the lung—in diseases such as asthma and chronic obstructive pulmonary disease (COPD)—as well as a description of the status of the current proteomics techniques. It also describes strategies for the discovery of disease markers that can be used to moni

Background: Previous studies and own clinical observations of patients with systemic lupus erythematosus (SLE) suggest that SLE harbors distinct immunophenotypes. This heterogeneity might result in differences in response to treatment in different subgroups and obstruct clinical trials. Our aim was to understand how SLE subgroups may differ regarding underlying pathophysiology and characteristic b

BACKGROUND: We hypothesized that reduced cerebral blood flow (CBF) and/or energy metabolic disturbances exist in the tissue surrounding a surgically evacuated intracerebral hemorrhage (ICH). If present, such CBF and/or metabolic impairments may contribute to ongoing tissue injury and the modest clinical efficacy of ICH surgery.OBJECTIVE: To conduct an observational study of CBF and the energy meta

Cigarette smoke is the most relevant risk factor for the development of lung cancer and chronic obstructive pulmonary disease. Many of its more than 4500 chemicals are highly reactive, thereby altering protein structure and function. Here, we used subcellular fractionation coupled to label-free quantitative MS to globally assess alterations in the proteome of different compartments of lung epithel

The chemical composition of calcium phosphate (CaP) materials for the regenerative therapy of large bone defects is similar to that of bone. Additionally, calcium phosphates show an excellent biocompatibility. Besides the support of defect healing calcium phosphate implants should be completely degraded within an adequate time period to be replaced by newly formed bone. Although degradation of CaP

It is increasingly apparent that technology and online platforms entail and communicate normativity. Lawrence Lessig has described this in terms of 'code as law' and thereby pointing to the fact that there is an ongoing shift of power from nation states to tech companies, and José van Dijck has shown how the Big Five - Google (Alphabet), Apple, Amazon, Facebook, Microsoft - represents a neo-liberaIt is increasingly apparent that technology and online platforms entail and communicate normativity. Lawrence Lessig has described this in terms of 'code as law' and thereby pointing to the fact that there is an ongoing shift of power from nation states to tech companies, and José van Dijck has shown how the Big Five - Google (Alphabet), Apple, Amazon, Facebook, Microsoft - represents a neo-libera

Gemmell and Naor proposed a new protocol for the authentication of long messages which was based on block codes and which used a transmission channel k times. This multiround authentication makes it possible to limit the key size independently of the message length. We propose a new attack and show that the probability analysis made by Gemmell and Naor, which was only based on the minimum distance

The internationalization of firms has led to boards becoming more international as well. In this study, we investigate the consequences of board internationalization. In particular, by drawing on research on language and board dynamics, we identify theory-based reasons why board internationalization could increase, or decrease, earnings management practices. We use agency theory, stressing how boa