Carbon release from the North Pacific in glacial-interglacial cycles has been mainly linked to the North Pacific Intermediate Water (NPIW) formation and associated carbon/nutrient water upwelling and biological productivity changes. However, relationship between NPIW and atmospheric CO2 change in the early interglacial remains unclear. Here we report a high-resolution sediment record of NPIW evolu

While the traditional consensus dictates that high ion concentrations lead to negligible long-range electrostatic interactions, we demonstrate that electrostatic correlations prevail in deep eutectic solvents where intrinsic ion concentrations often surpass 2.5 M. Here we present an investigation of intermicellar interactions in 1:2 choline chloride:glycerol and 1:2 choline bromide:glycerol using

For successful climate change adaptation, the distribution of responsibility within society is an important question. While the literature highlights the need for involving both public and private actors, little is still known of how citizens perceive their own and others’ responsibility, let alone the moral groundings for such perceptions. In this paper, we report the results of a survey regardin

Most mineral-Associated organic matter (MAOM) is protected against microbial attack, thereby contributing to longterm carbon storage in soils. However, the extent to which reactive compounds released by plants and microbes may destabilize MAOM and so enhance microbial access, as well as the underlying mechanisms, remain unclear. Here, we tested the ability of functionally distinct model exudates-l

Patients with childhood, adolescent, and young adult cancer who will be treated with gonadotoxic therapies are at increased risk for infertility. Many patients and their families desire biological children but effective communication about treatment-related infertility risk and procedures for fertility preservation does not always happen. The PanCareLIFE Consortium and the International Late Effec

Rapporten utgör den första av tre delrapporter och redovisar resultatet av forskning på uppdrag av Försvarsmakten.The report is the first of three sub-reports and presents the results of a research commissioned by the Swedish Armed Forces.

OBJECTIVE: To evaluate circumferential resection margin (CRM) as a risk factor for distant metastasis (DM) in rectal cancer.SUMMARY BACKGROUND DATA: The treatment of rectal cancer has evolved over the last decades. Surgical radicality is considered the most important factor in preventing recurrences including local and distant. CRM ≤1.0 mm is considered to increase recurrence risk. This study expl

Higher milk intake has been associated with a lower stroke risk, but not with risk of coronary heart disease (CHD). Residual confounding or reverse causation cannot be excluded. Therefore, we estimated the causal association of milk consumption with stroke and CHD risk through instrumental variable (IV) and gene-outcome analyses. IV analysis included 29,328 participants (4,611 stroke; 9,828 CHD) o

The genetic basis of bird migration has been the focus of several studies. Two willow warbler subspecies (Phylloscopus trochilus trochilus and Phylloscopus trochilus acredula) follow different migratory routes to wintering grounds in Africa. Their breeding populations overlap in contact areas or “migratory divides” located in central Scandinavia and in eastern Poland. Earlier analyses demonstrated

Condensation of DNA helices into hexagonally packed bundles and toroids represents an intriguing example of functional organization of biological macromolecules at the nanoscale. The condensation models are based on the unique polyelectrolyte features of DNA, however here we could reproduce a DNA-like condensation with supramolecular helices of small chiral molecules, thereby demonstrating that it

This text discusses the professional development of academic developers. It is based on the authors’ reflections and observations in the context of a semi-formal programme, Strategic Academic Development, held for academic developers in different regions of the world. Most recently the programme participants were academic developers in Singapore. In this text, we as authors share what we notice asThis text discusses the professional development of academic developers. It is based on the authors’ reflections and observations in the context of a semi-formal programme, Strategic Academic Development, held for academic developers in different regions of the world. Most recently the programme participants were academic developers in Singapore. In this text, we as authors share what we notice as

Researchers have raised concerns about mental health in elite athletes, including problem gambling, where research hitherto is scarce. While gambling has been assessed in the younger student-athlete population, neither gambling nor the recently recognized behavioral addiction of gaming disorder has been sufficiently addressed in the elite athlete population. The present systematic literature revie

Purpose: Infections from the oral microbiome may lead to exacerbations of chronic obstructive pulmonary disease (COPD). We investigated whether advanced dental cleaning could reduce exacerbation frequency. Secondary outcomes were disease-specific health status, lung function, and whether the bacterial load and composition of plaque microbiome at baseline were associated with a difference in outcom

Introduction: Pre-analytical sample handling might affect the results of Alzheimer's disease blood-based biomarkers. We empirically tested variations of common blood collection and handling procedures. Methods: We created sample sets that address the effect of blood collection tube type, and of ethylene diamine tetraacetic acid plasma delayed centrifugation, centrifugation temperature, aliquot vol

G.fast is a gap-bridging broadband technology on the way to a fully optical access network. G.fast is deployed in hybrid fiber-copper access networks and aiming to offer ubiquitous low-cost and high-speed broadband. For network operators, it is crucial to determine the location from where to deploy G.fast, the expected network coverage, and the expected bit rates. In this paper, we perform network

Introduction: Dual bronchodilators are recommended as maintenance treatment for patients with symptomatic COPD in the UK; further evidence is needed to evaluate cost-effectiveness versus monotherapy. Cost-effectiveness of umeclidinium/vilanterol versus umeclidinium and salmeterol from a UK healthcare perspective in patients without exacerbations in the previous year was assessed using post hoc EMA

We investigate the complex conductivity behaviour of natural volcanic rocks containing variable amounts of smectite in multi-salinity experiments. We compare the results with relationships established for sandstones. Considering only samples with little volume of metallic particles, we observe similar and small phase-angles at low frequency for all samples at all salinities (less than 25 mrad at 1

The underground circulation of hot water, of interest for geothermal energy production, is often indirectly inferred from the presence of minerals formed by hydrothermal alteration at different temperatures. Clay minerals, such as smectite and chlorite, can be mapped from the surface using electrical soundings and give information about the structure of the geothermal system. Here, we investigate