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Russian Flag at the North Pole

Russia’s planting of a flag on the seabed at the North Pole in 2007 set off a flurry of concern about its maritime and territorial ambitions and the potential for international conflict in the Arctic. However, the law of the sea now renders moot traditional rules of the doctrine of discovery and occupation as manifestations of sovereignty. Thus, the Russian flag at the North Pole is meaningless in

Controlled exposure reduces fear of brown bears

Fear of large carnivores such as brown bears may restrict people’s outdoor activities regardless of experts’ estimated risk of attack. This research study empirically examined three exposure interventions in the form of guided walks intended to give people living in brown bear areas tools for coping with their fear. All interventions significantly reduced fear, decreased people’s perceived vulnera

Three-year follow-up of visual outcome and quality of life in patients with age-related macular degeneration

Background: The purpose of this study was to evaluate the visual outcome and self-reported vision-targeted health status in patients treated with intravitreal ranibizumab for wet age-related macular degeneration (AMD). Methods: A total of 51 eyes from 50 patients aged 76 ± 7 years, with wet AMD not previously treated, were included in this prospective study. Best corrected visual acuity was examin

The role of OCT-A in retinal disease management

Optical coherence tomography angiography (OCT-A) is a non-invasive, non-dye-based imaging modality that has the potential to enhance our understanding of retinal diseases. While this rapidly advancing imaging modality offers great potential, there is a need for community-wide understanding of the range of technologies and methods for interpreting the images, as well as a need to enhance understand

Fimbriae reprogram host gene expression - Divergent effects of P and type 1 fimbriae

Pathogens rely on a complex virulence gene repertoire to successfully attack their hosts. We were therefore surprised to find that a single fimbrial gene reconstitution can return the virulence-attenuated commensal strain Escherichia coli 83972 to virulence, defined by a disease phenotype in human hosts. E. coli 83972pap stably reprogrammed host gene expression, by activating an acute pyelonephrit

Eternit

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Can Salvator Mundi and Zlatan make Built Cultural Heritage resilient?

Can Salvator Mundi and Zlatan make Built Cultural Heritage resilient? The new role of built cultural heritage (BCH), as an economic asset for development strategies and the widened definition as a concept-, explains today’s affluence of sites. These can only be guaranteed with sufficient heritage funding. Financers’ inducement to fund depends on that heritage’s current value estimation and only hi