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Separating the Future: Socialism, Valuation, and Conflict
While social movement scholars have long recognized the importance of collective memory and shared pasts in the construction of collective identities, less attention has focused on the role of imagined futures. Based on a long-term ethnographic study of radical left-libertarian groups in Sweden, this paper explores the role of utopia in structuring, influencing, and evaluating actions and practice
Semiotics, psychotherapy and Levinas’s ethics of “The Other”
The aim of this chapter is to show how insights from semiotics cancontribute to psychotherapy, notably the one inspired by Emmanuel Levinas’sethics of the other. Important to this undertaking are Augusto Ponzio’ssemiotic analyses of the ethics of Levinas. Moreover, a study of the Peirceannotion of abduction has proved to be fruitful in the further understanding ofhow psychotherapy can benefit from
Social and Emotional Learning in Preschool Settings : A Systematic Map of Systematic Reviews
The preschool years presents an important opportunity to support children’s social and emotional development. Social and emotional learning (SEL) programs in early childhood education and care (ECEC) have gained an increased interest due to its potential to improve child health and educational outcomes. We aimed to identify existing systematic reviews on universal, curriculum-based SEL interventio
DIAGNOSTIC RELIABILITY OF MEASUREMENT OF PREMATURE VENTRICULAR COMPLEX FREQUENCY RELATED TO DURATION OF AMBULATORY MONITORING
Background Premature ventricular complexes (PVCs) are generally quantified using a 24h ECG recording, but the diagnostic accuracy is unknown. We aimed to determine the day-to-day variability and optimal monitoring duration for PVC measurements among patients with frequent PVCs. Methods We included all patients who underwent a clinical ambulatory ECG recording lasting 25-30 days, using the PocketEC
Enhanced orbital anisotropy through the proximity to a SrTi O3 layer in the perovskite iridate superlattices
We have used angle-dependent soft x-ray absorption spectroscopy (XAS) at the O K edge and first-principles calculations to investigate the electronic structures of iridate-based superlattices (SrIrO3)m/(SrTiO3) (m=1, 2, 3, and ∞). We focus on the pre-edge Ir 5d t2g-O 2p orbital hybridization feature in the XAS spectra. By varying the measurement geometry relative to the incident photon polarizatio
Coins in church contexts : Hedensted Church, Jutland, Denmark
”En ineffektiv åtgärd i klimatarbetet”
Vi välkomnar repliken från Carbon Capture Companys vd. Vi, EU, Sveriges regering och Christoffer Bonde delar målet att främja ett starkt och lönsamt skogsbruk som bidrar till klimatarbetet både genom upptag av växthusgaser och minskade utsläpp. Vad vi ställer oss kritiska till är den klimatkompensation som just nu lanseras av företag som Carbon Capture Company, eftersom vi anser att den är dyr,
Somatic mutation of immunoglobulin V genes in vitro
The molecular mechanism behind affinity maturation is the introduction of point mutations in immunoglobulin (Ig) V genes, followed by the selective proliferation of B cells expressing mutants with increased affinity for antigen. An in vitro culture system was developed in which somatic hypermutation of Ig V genes was sustained in primed B cells. Cognate T cell help and cross-linking of the surface
The effect of carrier and carrier priming on the kinetics and pattern of somatic mutation in the V chi Ox1 gene
Priming mice with a chicken gamma globulin (CGG) carrier protein significantly accelerated the onset of somatic mutation in the V chi Ox1 gene when the mice were subsequently immunized with 2-phenyl-5-oxazolone (phOx) coupled to CGG. The first mutations were already detected 7 days after immunization, while in the true primary response, they are not apparent until day 10. It was also found that co
Cell-cycle kinetics of proliferating mouse B lymphocytes in vitro
Resting mouse B lymphocytes were stimulated in vitro with lipopolysaccharide, Sepharose-coupled anti-kappa antibodies or a combination of the two. B lymphocytes stimulated with anti-kappa entered the cell-cycle with more rapid kinetics and at a higher frequency than did the corresponding cell population stimulated with lipopolysaccharide. Using cell cycle analysis after DNA staining combined with
T-cell receptor repertoire in human germinal centres
A search for an antigen-driven expansion of T lymphocytes in the inflamed joints in rheumatoid arthritis (RA) patients have been going on for decades. We here analyzed the human germinal centre T-cell receptor (TCR) Vbeta gene usage with polymerase chain reaction (PCR) combined with sequence analysis, to address the question of clonality in tonsils and synovial tissue from RA patients. Our data sh
Expansion of kappa + B cells during the primary immune response to 4-hydroxy-3-nitrophenyl acetate in BALB/c mice
Analysis of somatic mutation activity in multiple V kappa genes involved in the response to 2-phenyl-5-oxazolone
We have studied somatic mutation activity early in a response to 2-phenyl-5-oxazolone coupled to ovalbumin (phOx-OVA). Although the V kappa Ox1 gene rearranged to J kappa 5 is known to predominate in this response, other closely related V kappa genes are involved. We compared the introduction of point mutations into V kappa Ox1 genes and into a set of related V kappa genes rearranged to the same J
Change in the Th1/Th2 phenotype of memory T-cell clones from rheumatoid arthritis synovium
The stability of established memory T helper (Th)1/Th2 cells in chronic inflammatory diseases is not clear, and a shift of the cytokine balance could control chronic inflammation. In order to study the regulation of the Th phenotype of memory T cells, polyclonal T-cell lines and clones with a Th1, Th0 or Th2 phenotype were developed from rheumatoid synovial tissue. Th1 [interleukin (IL)-12 + anti-
Kinetics of somatic mutation in lymph node germinal centres
Somatic mutation activity in immunoglobulin V kappa genes during the response to the hapten 2-phenyl-5-oxazolone was measured in lymph node B-cell populations at various timepoints after footpad immunization. When the V kappa Ox1 genes rearranged to the J kappa 5 segment were amplified from genomic DNA using the polymerase chain reaction and sequenced, somatic mutations could be detected as early
Expansion, selection and mutation of antigen-specific B cells in germinal centers
Heterodox transients in time-domain induced polarization
Negative induced polarization (IP) time-domain transients, sign-changing or non-monotonically decaying transients are currently often considered as measurement errors and removed in the data processing. These transients, here named heterodox in the sense of other than generally accepted signals, might originate from measurement errors, inductive effects, or poor signal processing, but synthetic mo
Remissyttrande: Yttrande över God och nära vård - Rätt stöd till psykisk hälsa (SOU 2021:61)
Evolving escherichia coli host strains for efficient deuterium labeling of recombinant proteins using sodium pyruvate-d3
Labeling of proteins with deuterium (2H) is often necessary for structural biology tech-niques, such as neutron crystallography, NMR spectroscopy, and small-angle neutron scattering. Perdeuteration in which all protium (1H) atoms are replaced by deuterium is a costly process. Typ-ically, expression hosts are grown in a defined medium with heavy water as the solvent, which is supplemented with a de
