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Mounting Evidence for Synthetic Mammography in Breast Cancer Screening
Neoadjuvant breast cancer treatment response; tumor size evaluation through different conventional imaging modalities in the NeoDense study
Neoadjuvant chemotherapy (NACT) is offered to an increasing number of breast cancer (BC) patients, and comprehensive monitoring of treatment response is of utmost importance. Several imaging modalities are available to follow tumor response, although likely to provide different clinical information. We aimed to examine the association between early radiological response by three conventional imagi
Suppressed competitive exclusion enabled the proliferation of Permian/Triassic boundary microbialites
During the earliest Triassic microbial mats flourished in the photic zones of marginal seas, generating widespread microbialites. It has been suggested that anoxic conditions in shallow marine environments, linked to the end-Permian mass extinction, limited mat-inhibiting metazoans allowing for this microbialite expansion. The presence of a diverse suite of proxies indicating oxygenated shallow se
En förbindelse med en större värld : Postorder i Sverige under tidigt 1900-tal
This thesis examines mail order in early 20th-century Sweden from the perspective of media history. Its aim is to study the mediated encounter between the foremost mail-order company in Sweden, Åhlén & Holm, and its audience, in order to answer the question of what this mediated link meant for the living conditions and conceptual worlds of the contemporary audience, as well as for the advancem
Author response to : Comment on: Impact of rectal perforation on recurrence during rectal cancer surgery in a national population registry
Insulin secretion : The nitric oxide controversy
Nitric oxide (NO) is a gas that serves as a ubiquitous signaling molecule participating in physiological activities of various organ systems. Nitric oxide is produced in the endocrine pancreas and contributes to synthesis and secretion of insulin. The potential role of NO in insulin secretion is disputable – both stimulatory and inhibitory effects have been reported. Available data indicate that e
Price premiums for eco-labelled seafood: effects of the MSC certification suspension in the Baltic Sea cod fishery
Certification programmes in fisheries have been introduced as a market-based tool for promoting sustainable fishing practices. While consumers appreciate the eco-labels by paying a price premium in the retail market, there is not much research on whether the premium transmits to the fishing industry. This paper adds to the literature by studying price premiums at port for the Swedish Baltic Sea co
Patch testing with a textile dye mix with and without Disperse Orange 3
Background: The textile dye mix (TDM) 6.6% pet. contains Disperse Blue (DB) 35, Disperse Yellow 3, Disperse Orange (DO) 1 and 3, Disperse Red 1 and 17, and DB 106 and 124. The most frequent allergen in TDM-positive patients is DO 3. Around 85% of p-phenylenediamine (PPD)-allergic dermatitis patients have shown positive patch test reactions to DO 3. There has been a discussion to exclude DO 3 from
Individual and Contextual Factors Associated With Hazardous Drinking in Spain : Evidence From a National Population-Based Study
BACKGROUND: Heavy drinking (HD) and binge drinking (BD) exhibit marked differences in their relationships with contextual-level factors imbedded in geographical areas of residence. The objective is to identify sociodemographic factors, both at the individual and at the contextual level, associated with these 2 main hazardous consumption patterns.METHODS: Cross-sectional study using data from the 2
If we don’t change direction soon, we’ll end up where we’re going : a description of the SSY Engine
Data presented during the first two decades of this millennium has shed valuable light on how the intraocular pressure (IOP) is linked to glaucomatous progression. Large prospective controlled trials have confirmed that there is a correlation between the change in intraocular pressure (IOP) and the risk for visual field progression. The magnitude of the effect, as indicated by these studies, is a
Three cases of Charles Bonnet Syndrome in patients with advanced glaucomatous visual field loss but preserved visual acuity
Purpose: To describe three cases of Charles Bonnet syndrome (CBS) in glaucoma patients with preserved visual acuity. Methods: Three glaucoma patients who had taken part in a recent CBS study were interviewed about their hallucinations. The patients underwent macular optical coherence tomography (OCT) of both eyes. The visual function was evaluated with visual field measurement (Humphrey visual fie
Acute phase markers in CSF reveal inflammatory changes in Alzheimer's disease that intersect with pathology, APOE ε4, sex and age
It is unknown how neuroinflammation may feature in the etiology of Alzheimer's disease (AD). We profiled acute phase response (APR) proteins (α1-antitrypsin, α1-antichymotrypsin, ceruloplasmin, complement C3, ferritin, α-fibrinogen, β-fibrinogen, γ-fibrinogen, haptoglobin, hemopexin) in CSF of 1291 subjects along the clinical and biomarker spectrum of AD to investigate the association between infl
Photopatch testing in a tropical country, Thailand : 20 years' experience
Background: Photoallergic contact dermatitis is one of the important parts of photodermatoses. The investigation of choice is photopatch testing. However, reports with photopatch test results from Asian countries are scarce. The objective of this study was to determine the prevalence of positive photopatch test reactions and to ascertain the common photoallergens among Thai patients during 1998-20
Type 2 inflammatory biomarker response after exercise challenge testing
Introduction: Exercise-induced bronchoconstriction is due to osmotic stimulus of the airway epithelium and leads to a cascade of biomarker release from several inflammatory cells. Several type 2 (T2) mediators have been linked to exercise-induced bronchoconstriction, but the T2 response per se has not been described during exercise. The aim of this study was therefore to investigate T2 biomarkers
Chlamydial contribution to anaerobic metabolism during eukaryotic evolution
The origin of eukaryotes is a major open question in evolutionary biology. Multiple hypotheses posit that eukaryotes likely evolved from a syntrophic relationship between an archaeon and an alphaproteobacterium based on H2 exchange. However, there are no strong indications that modern eukaryotic H2 metabolism originated from archaea or alphaproteobacteria. Here, we present evidence for the origin
Pandemin visar att stads- och samhällsplanering måste ha större helhetsperspektiv
Just nu finns det en möjlighet för politikerna att lägga om stadsplaneringen så att det blir möjligt att nå FN:s hållbarhetsmål. Det skriver åtta forskare som arbetar med miljö- och hälsofrågor.
Remissyttrande: Uppföljning till Underlag för inhämtning av synpunkter rörande genomförandet av artikel 17 i EU:s nya upphovsrättsdirektiv
Remissyttrande: Grundpension – Några avslutande frågor (SOU 2020:32)
Harmonisation of 3D geodata : a prerequisite for a digital information flow for applications in the planning and building sector
Dataharmonisering är en förutsättning för smarta städer, för ett mer effektivt informationsflöde i samhällsbyggnadsprocessen och för många andra tillämpningar i en stadsmiljö. Vid ett bästa tänkbart scenario kommer dataharmonisering att resultera i ett digitalt informationsflöde som inkluderar information från ett objekts hela livscykel, till exempel för byggnader, vägar och tunnlar. Alla aktörer Data harmonisation is a prerequisite for smart cities, for a more efficient information flow in the planning and building process and for many applications in the urban environment. Ideally, data harmonisation will result in a digital information flow that include information from the whole lifecycle of a feature, for example for buildings, roads and tunnels. All actors and applications involved i