The gene of the protease inhibitor SKALP/elafin is a member of the REST gene family
Members of the REST gene family characteristically have a transcription unit consisting of three exons. The first and the last exon are conserved among members, while the second exon--encoding almost all of the mature protein--differs considerably. The so far known REST genes are highly, and almost exclusively, expressed in the seminal vesicles. By sequence analysis we have now identified the gene