The basis for the hypoxic relaxation of spontaneous activity in the rat portal vein was investigated by comparing responses to oxygen and the respiratory chain inhibitors amobarbital and cyanide. With the inhibitors, O2 consumption (FO2) is uniformly decreased throughout the cell mass, and thus O2 gradients in the tissue are avoided. Hence the effects are not to be attributed to all-or-none inhibi

Since akinete germination is triggered by light and the action spectrum for this process has features in common with the spectra of the two photochromic pigments, phycochromes b and d, a search was made for the presence of these phycochromes in akinetes of the blue-green alga. Anabaena variabilis Kützing. Allophycocyanin-B was also looked for, since the action spectrum for akinete germination poin

Accelerator mass spectrometry (AMS) is an ultra-sensitive method for counting atoms, both radionuclides and stable nuclides. When using small tandem accelerators to measure heavy isotopes, interfering isobars are often troublesome. One way to reduce this interference is to combine AMS with the detection of characteristic X-rays of the projectile. After analysis in the AMS system it is possible to

The metabolism of a group of quinoline 3-carboxamide derivatives was evaluated in liver microsomes from various species. In addition, metabolism data were compared with in vivo pharmacokinetics in the mouse. The studied compounds were metabolized by cytochrome P450 enzymes. Microsomal clearance was low and seemed independent of a substituent in the quinoline moiety, whereas clearance was enhanced

Five Swedish patients with chronic hepatitis C were prospectively followed until hepatocellular carcinoma (HCC) developed. Hepatitis C virus (HCV) antibodies were analysed by a second generation anti-HCV ELISA and a recombinant immunoblot assay (RIBA-2) and viraemia by detection of serum HCV RNA by polymerase chain reaction. Four patients had post transfusion hepatitis and in one patient the sourc

Syftet med denna avhandling är att analysera hur berättelser om skyldiga och oskyldiga mödrar konstruerades under perioden ca. 1680-1800. De två brottskategorierna barnamord och barnkvävning har undersökts. Källmaterialet har huvudsakligen bestått av protokoll från hovrätten, underrätter och sockenstämmor. Jag har klarlagt vilka omständigheter som utreddes vid brottsutredningarna och fick betydelsThe objective of this thesis is to analyse how judicial texts concerning guilty and innocent mothers were constructed during the period of c. 1680-1800. The two crimes of infanticide and overlaying have been examined. Source materials have primarily consisted of proceedings from the appeals court, courts of first instance, and parish meetings. The aim has been to survey the judicial discourse, tha

The association between baseline levels of eleven bone turnover markers and 5-year rate of bone density change was prospectively studied in a population-based sample of 601 75-year-old women. Several bone formation and resorption markers as well as urinary osteocalcin were modestly correlated to rate of bone density change. Introduction Prediction of bone loss by bone turnover markers (BTMs) has b

This thesis is focused on natural killer (NK) T cells. NKT cells recognize lipids and glycolipids, rather than peptides, in the contents of the antigen presenting molecule CD1d. NKT cells have a surface phenotype reminiscent of memory cells, and have been shown to rapidly produce large amounts of cytokines, such as IL-4 and IFN-gamma, upon activation. Because of their rapid response to activation,

Analysis of conceptual and methodological principles in the study of Christian mission and ecumenism in Lund University

Effects of ultraviolet (UV)-B radiation and acidification on pelagic carbon flux in a humic lake (dissolved organic carbon [DOC] similar to15 mg C L-1) were studied in a mesocosm experiment during the summer of 2000. Triplicate tanks (107 liters volume, 1 m high) were exposed to natural solar radiation, a daily extra dose of UV-B radiation, or kept dark. One set of tanks was submitted to a decreas

Popular Abstract in Swedish I denna avhandling studeras förändringar i individers religiositet i samband med migration och vad som orsakar sådana förändringar. Det huvudsakliga materialet för studien består av intervjuer med sverige-chilenare boende i Malmö-Lundområdet, vilka berättat om vad som skett med deras religiositet efter ankomsten till Sverige. I arbetet ingår även en brevenkät till sveriThe purpose of this study is to examine changes related to migration in the religiosity of individuals and what lies behind such changes. The study is foremost based on interviews with 23 Swedish-Chileans who have lived in Sweden for an extended period of time and who were adults when they immigrated to Sweden. The interviews are thematic life stories. Each one of the individuals narrates his or h

Aims: In a population of middle-aged women a survey was carried out to ascertain the prevalence of mental symptoms and psychotropic drug use, and further to investigate whether severe mental symptoms are associated with social situation, alcohol consumption, smoking, and physical health. Methods: All women (n510,766) aged 50-59 years and living in the Lund area were invited to the WHILA study, a h

Inclusive jet production is studied in neutral current deep-inelastic positron-proton scattering at large four momentum transfer squared Q(2) > 150 GeV2 with the H1 detector at HERA. Single and double differential inclusive jet cross sections are measured as a function of Q(2) and of the transverse energy E-T of the jets in the Breit frame. The measurements are found to be well described by calcul

A new method for noise reduction using spatiotemporal smoothing is presented in this paper. The method is developed especially for reducing the noise that arises when acquiring video sequences with a camera under very dim light conditions. The work is inspired by research on the vision of nocturnal animals and the adaptive spatial and temporal summation that is prevalent in the visual systems of t

With the characterization of the total genomes of Arabidopsis thaliana and Oryza sativa, several putative plasma membrane components have been identified. However, a lack of knowledge at the protein level, especially for hydrophobic proteins, have hampered analyses of physiological changes. To address whether protein complexes may be present in the native membrane, we subjected plasma membranes is

Popular Abstract in Swedish Denna avhandling beskriver studier av de mekanismer varmed bakterien Streptococcus pyogenes undviker komplementdeposition och fagocytos.Phagocytosis of Streptococcus pyogenes is complement dependent. However, the cell wall-associated M protein, which exists in >100 different serotypes (M types), enables the bacteria to evade phagocytosis. To analyze the mechanisms by which M protein confers this ability we used, as model systems, two representative M proteins, the M22 and M5 proteins, which have properties typical for many M prote