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Introduction: Chagas disease, caused by Trypanosoma cruzi, remains a significant public health challenge, particularly among socioeconomically disadvantaged populations in developing countries. Although two drugs are currently available, their use is associated to severe side effects, and they are only widely accepted as a treatment against the acute phase of the disease. Background: A Waltherione

Head and neck squamous cell carcinoma (HNSCC) is a heterogenous cancer with poor prognosis, especially for patients with advanced or recurrent disease. The complex tumor microenvironment (TME) plays an important role in mediating immune evasion and therapy resistance. To improve preclinical testing, advanced 3D in vitro and ex vivo models such as spheroids, organoids, and tumor slice cultures have

Youth delinquency constitutes a significant social problem, both internationally and nationally. This study explored risk and protective factors that influenced youth involvement in criminal behaviour. The study was based on semi-structured interviews with eight family therapists within social services in Sweden, all of whom had experience with young men involved in youth delinquency. The analysis

Although most homes still appear visually the same as they did a half century ago, their relationship to humans and their surrounding environment has changed significantly in recent years. Conventional residential design is often constrained by rigid layouts, poor adaptability to evolving lifestyles, and insufficient opportunities for individual personalization. As a result, spatial arrangements t

This master’s thesis is a cultural analysis of individuals with Type 1 diabetes, who use Continuous Glucose Monitors (CGM). It focuses on how these devices shape both individual and collective identities within the diabetes community, and beyond. Using a combination of interviews, observations, and a visual ethnographic approach such as participant-designed sketches, this research explores the rol

Följande studie undersökte hur självförtroende påverkar risken för att drabbas av choking under press i lagidrott, samt vilka strategier idrottare använder för att hantera sådana situationer. Semistrukturerade intervjuer genomfördes med fem aktiva kvinnliga rugbyspelare på elitnivå. Datamaterialet analyserades tematiskt för att undersöka idrottarnas subjektiva upplevelser av press, självförtroendeThe present study examined how confidence influences the risk of choking under pressure in team sports, and what strategies athletes use to cope with such situations. Semi-structured interviews were conducted with five elite female rugby players. The data were analysed thematically to explore athletes' subjective experiences of pressure, confidence, and performance. Four main themes were ident

Syfte: Studiens syfte var att bidra med ökad kunskap om narrativ förmåga hos ungdomar i åldrarna 13-17 år. Metod: I studien deltog 25 ungdomar från årskurs 7 upp till andra året på gymnasiet. Information om ungdomarnas ålder, kön, eventuell flerspråkighet, eventuella neuropsykiatriska funktionsnedsättningar (NPF) och vårdnadshavares utbildningsnivå samlades in via en enkät. Deltagarna berättade tiPurpose: The aim of the study was to increase our knowledge of narrative ability in adolescents aged 13-17 years. Method: Twenty-five adolescents from grade 7 to the second year of high school participated. Information about the adolescents' age, gender, language status, any neuropsychiatric disabilities and the caregivers' educational level was collected via a questionnaire. The participa

Streptococcus pneumoniae and Streptococcus pyogenes are Gram-positive bacteria responsible for a wide spectrum of diseases, ranging from mild to even life-threatening. The annual global mortality rates of the bacteria amount to 1.68 million. While vaccines against S. pneumoniae are included in our medical arsenal, their efficacy is limited by poor immune responses in certain age groups or insuffic

Syfte: Entrustable professional activities (EPA) är beskrivningar av arbetsuppgifter väsentliga till en profession. Syftet med studien var att ta fram förslag på logopediska EPAutifrån arbetsuppgifter som deltagarna fått erfara i sin verksamhetsförlagda utbildning (VFU) eller i sitt arbete inom den logopediska verksamheten. Syftet var också att kartlägga om och hur studenter på logopedprogrammet vPurpose: Enstrustable professional activities (EPA) are descriptions of work tasks essential to a profession. The purpose of this study was to suggestEPA for speech-language pathology based on tasks that the participants have performed during their clinical practice or in their work as speech-language pathologists (SLPs), and to investigate if and how students of the SLP program at Lund University

In the last ten years, Sweden has seen a noticeable increase in shootings involving young people, which has led to growing media attention and public concern. This thesis explores how Swedish newspapers frame these shootings and how those frames align with public discourse in an online forum in Sweden. The study examines the connection between media framing of youth-involved shootings and public d

Syfte: Uppsatsens syfte var att undersöka vilken ordavkodningstrategi som främst tillämpas av elever i årskurs 3 samt om avkodningsstrategin modifierats från årskurs 2 till 3. Studiens syfte var även att utforma en metod för att på ett tillförlitligt sätt kunna bedöma och analysera elevernas avkodningsstrategier. Metod: Deltagarna bestod av 111 elever som deltog vid två tillfällen (årskurs 2 och 3Purpose: The aim of this study was to investigate which word decoding strategy is primarily used by students in grade 3, as well as to examine whether their decoding strategy changed from grade 2 to grade 3. The study also aimed to develop a reliable method to assess and analyze students’ decoding strategies. Method: The participants consisted of 111 students who participated on two occasions (gra

This thesis critically engages with the concept of forgiveness in the context of reconciliation between Aboriginal and Torres Strait Islander Peoples and non-Indigenous Australians. It examines first the historical development of reconciliation efforts between Indigenous and white Australia and shows a discrepancy between their approaches. Where First Nations Australians emphasise concrete structu

In this thesis, proton-proton collisions at 7 TeV are simulated using PYTHIA. Charm and anticharm quarks are identified as being produced from direct, meaning that the charm and anticharm are pair produced by a hard scattering, or indirect interactions where the charm and anticharm pair is produced from the splitting of a single gluon. This data is used to generate a pT spectrum and correlation fu

Bakgrund: Aktivitetsbalans är avgörande för individens välbefinnande, särskilt vid kroniska sjukdomstillstånd som multipel skleros (MS). Aktivitetsbalans beskrivs som en relation mellan önskad och faktisk tidsanvändning inom olika aktiviteter. Fatigue är ett vanligt symtom vid MS och innebär en omfattande hjärntrötthet. Fatigue kan påverka aktivitetsbalans och livskvalitet negativt. Syfte: SyftetBackground: Occupational balance is crucial for an individual's well-being, especially in chronic diseases such as multiple sclerosis (MS). Occupational balance is described as a relationship between desired and actual time spent in different activities. Fatigue is a common symptom in MS and involves extensive brain fatigue. Fatigue can negatively affect occupational balance and quality of lif

Då byggbranschen står för en femtedel av den svenska ekonomins totala årliga växthusgasutsläpp, har sektorn en avgörande roll i arbetet mot en hållbar utveckling. Klimatpolitiska mål och styrmedel har tagits fram i syfte att leda branschen mot den hållbara utvecklingen. Lagstadgade klimatdeklarationer och gränsvärden för byggnaders klimatpåverkan är styrmedel för Sveriges färdplan mot uppfyllandetThe construction industry is responsible for approximately 20% of Sweden’s annual greenhouse gas emissions and plays a key role in achieving national climate goals. As building operations become more energy efficient, emissions from the construction phase, particularly from concrete frameworks become increasingly significant. This thesis investigates emission reducing alternatives for a fully pref

”Evighetskemikalierna” PFAS har uppmärksammats mer och mer de senaste åren och behovet för reningstekniker är viktigare är någonsin. Uppgiften är dock utmanande, bland annat på grund av att PFAS är svåra att bryta ner och har spridits över stora områden. Denna studie har undersökt möjligheten att rena PFAS-förorenade områden genom växter, med utgångspunkt i hur väl en växtodling på MSB Revinge utaPFAS (per- and polyfluoroalkyl substances) are a group of synthetically manufactured chemicals contributing to environmental pollution. The largest point source of PFAS in Sweden is the usage of firefighting foam, and at MSB (Swedish Civil Contingencies Agency) Revinge, firefighting foam has frequently been used. Moreover, PFAS is known to accumulate in plants, and a Salix plant cultivation has be

Implantat som bryts ner i kroppen – en lösning för framtidens benbrott Tänk dig att du bryter benet och att skruven som håller det på plats försvinner av sig själv när benet läkt – utan en extra operation. Det kan bli verklighet med nedbrytbara metallimplantat. Vid komplicerade benbrott används ofta metallimplantat för att stabilisera skelettet under läkningen. Dessa tillverkas traditionellt av Biodegradable magnesium alloys are promising candidates for orthopaedic implants due to their mechanical compatibility with bone and their bioresorbable nature. This study investigates the degradation behaviour of Mg-Zn-Zr-Ca alloys with varying zinc concentrations, focusing on how heat treatment and microstructure evolution influence corrosion resistance under physiologically relevant conditions.

Som vi har märkt på grund av de senaste årens höga elpriser är en jämn elproduktion från grön energi väldigt viktig. Solkraft där man lagrar energi i smält salt kan användas för att sprida ut eltillverkningen på alla dygnets timmar. Utvinningen av saltets energi är då högst betydelsefull och denna har undersökts genom effektiva och simpla flödessimuleringar i detta arbete. Dessa flödessimuleringaTo be able to meet the global energy demands, a steady supply of green energy is required, even during sun- or windless hours. Concentrated solar power is a useful alternative, which can produce and store green energy by heating a heat transfer fluid (HTF) and extracting its energy via a heat exchanger. One such category of HTF is molten salts, and to understand and be able to model the behaviour

Ett protein med potential: så kan växternas hemoglobin förändra världen Från blodbrist till vegetarisk kost uppmanas vetenskapen ständigt att hitta lösningar som främjar både hälsa och hållbarhet. En spännande möjlighet finns i phytoglobiner; växternas egna form av hemoglobin. I det här projektet har ett phytoglobin från sockerbeta producerats och optimerats i bakterier, med målet att ta fram ettHemoglobins, part of the globin superfamily, are heme-containing proteins that are involved in numerous biological processes, primarily oxygen transport. In plants, they are known as phytoglobins and serve diverse roles beyond oxygen transportation, with potential applications as artificial blood substitutes, iron supplements, and plant-based meat alternatives. A class 1 phytoglobin from sugar bee

Plastic has been a revolutionary material in human history. Plastic materials have several desirable properties, such as durability, low production costs, and versatility. This helps explain the increase in their use and production over the past 100 years. Plastics are synthetic polymers, with long repeating chains of monomers; this creates structures that are chemically stable and durable. The ov