Purpose:To find out differences in cerebral blood volume (CBV) maps derived from dynamic susceptibility contrast-enhanced magnetic resonance imaging (DSCE-MRI) in glioblastomas and cerebral metastases. The main purpose was to compare CBV maps between metastases with different primary malignancies. Furthermore the metastasis group was compared with the glioblastoma group.Method:Conventional imaging

Centrum för kommunstrategiska studier (CKS) har i två decennier verkat som ett centrum för forskning och samverkan vid Linköpings universitet. CKS bedriver forskning med målet att fördjupa strategiskt relevant kunskap för en långsiktigt hållbar samhällsutveckling. Det gör vi genom akademiska fora och genom samverkan med kommuner och regioner. Genom det långsiktiga stödet från Linköpings universiteThe municipalities of Sweden are in motion. Some are growing strongly, while others shrink. The population's composition changes. The municipalities are becoming more different, which raises questions about structure and self-government. Climate and sustainability issues will be more central and how should the municipalities be governed in order to meet future demands for financial stability,democ

Women are generally seen as less inclined to join trade unions. This study matches firm–worker data from the Swedish cigar and printing industries around 1900 and examines information on men and women holding the same jobs; such data are rare but important for understanding gender gaps. The results explain the gender gap in union membership among compositors, but not among cigar workers. Differenc

This special issue follows on from a special call for contributions to the ECER 2016 conference in Dublin on the need to rethink and reconceptualise internationalisation in higher education (HE). The papers in this special issue contribute to a critically reflective interdisciplinary discussion on the phenomena ofinternationalisation in terms of the evolution of the structures, systems, and functi

Objectives: To describe the process and outcomes of using a new evidence base to develop scientific guidelines that specify the type and minimum dose of exercise necessary to improve fitness and cardiometabolic health in adults with spinal cord injury (SCI). Setting: International. Methods: Using Appraisal of Guidelines, Research and Evaluation (AGREE) II reporting criteria, steps included (a) det

Research conducted in recent years has documented the widespread presence of various forms of color vision in species from across the animal kingdom, helped to develop an understanding of the basic biological mechanisms that underlie this sensory capacity, and provided some insights into the utility of color vision in the natural world. This chapter draws information from all these various sources

It is not known exactly where amyloid-β (Aβ) fibrils begin to accumulate in individuals with Alzheimer's disease (AD). Recently, we showed that abnormal levels of Aβ42 in cerebrospinal fluid (CSF) can be detected before abnormal amyloid can be detected using PET in individuals with preclinical AD. Using these approaches, here we identify the earliest preclinical AD stage in subjects from the ADNI

Multilevel data occur frequently in many research areas like health services research and epidemiology. A suitable way to analyze such data is through the use of multilevel regression models. These models incorporate cluster-specific random effects that allow one to partition the total variation in the outcome into between-cluster variation and between-individual variation. The magnitude of the ef

Forskningen i denna avhandling handlar i hög grad om att försöka härma kemin i jordens atmosfär. Den sista mätningen till denna avhandling gjordes för bara några veckor sedan, under ett fruktmellanmål tillsammans med mina barn. Jag bestämde mig för att testa ett otroligt påstående som säger att om jorden krymptes ihop till ett äpple är atmosfären lika tunn som äpplets skal. D.v.s.:tjocklek(äppleskApart from gases, the air we breath consist of tiny, so called, aerosol particles. A cubic metre of air in a relatively clean environment can consist of several billion aerosol particles. The impact of these particles on human health and on climate is significant. According to WHO, particles affect more humans than any other pollutant, and is closely related to mortality and morbidity. Further, it

The pre-industrial millennium is among the periods selected by the Paleoclimate Model Intercomparison Project (PMIP) for experiments contributing to the sixth phase of the Coupled Model Intercomparison Project (CMIP6) and the fourth phase of the PMIP (PMIP4). The past1000 transient simulations serve to investigate the response to (mainly) natural forcing under background conditions not too differe

This thesis focuses on algorithms and proofs of concepts in the area of wireless systems operating with a large number of antennas, especially at the base station side.The first studied topic concerns the design and implementation of massive multiple-input multiple-output (MIMO) testbeds, primarily for communications. This is an entirely new engineering challenge on its own, due to the unprecedent

Abstract Drawing on the concept of decoupling, from institutional theory in organizational studies, this paper explains how organizations mitigate demands for circularity. Seven Swedish apparel companies that have started collecting used clothes as a form of engagement with circular business models serve as case studies. The paper shows how outsourcing and internal separation allow these companies

Background: The term prurigo has been used for many decades in dermatology without clear definition, and currently used terminology of prurigo is inconsistent and confusing. Especially, itch-related prurigo remains unexplored regarding the epidemiology, clinical profile, natural course, underlying causes, available treatments and economic burden, although burdensome and difficult to treat. Objecti

Natriuretic peptides (NPs) are important hormones that regulate multiple cellular functions including cardiovascular physiology. In the heart, two natriuretic peptide receptors NPR1 and NPR2 act as membrane guanylyl cyclases to produce 3′,5′-cyclic guanosine monophosphate (cGMP). Although both receptors protect from cardiac hypertrophy, their effects on contractility are markedly different, from l