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First-order synchronization transition in a large population of strongly coupled relaxation oscillators

Onset and loss of synchronization in coupled oscillators are of fundamental importance in understanding emergent behavior in natural and man-made systems, which range from neural networks to power grids. We report on experiments with hundreds of strongly coupled photochemical relaxation oscillators that exhibit a discontinuous synchronization transition with hysteresis, as opposed to the paradigma

Understanding the dynamics of biological and neural oscillator networks through exact mean-field reductions : a review

Many biological and neural systems can be seen as networks of interacting periodic processes. Importantly, their functionality, i.e., whether these networks can perform their function or not, depends on the emerging collective dynamics of the network. Synchrony of oscillations is one of the most prominent examples of such collective behavior and has been associated both with function and dysfuncti

Cerebrospinal fluid influx drives acute ischemic tissue swelling

Stroke affects millions each year. Poststroke brain edema predicts the severity of eventual stroke damage, yet our concept of how edema develops is incomplete and treatment options remain limited. In early stages, fluid accumulation occurs owing to a net gain of ions, widely thought to enter from the vascular compartment. Here, we used magnetic resonance imaging, radiolabeled tracers, and multipho

Directed Flow of Information in Chimera States

We investigated interactions within chimera states in a phase oscillator network with two coupled subpopulations. To quantify interactions within and between these subpopulations, we estimated the corresponding (delayed) mutual information that—in general—quantifies the capacity or the maximum rate at which information can be transferred to recover a sender's information at the receiver with a van

Chaos in Kuramoto oscillator networks

Kuramoto oscillators are widely used to explain collective phenomena in networks of coupled oscillatory units. We show that simple networks of two populations with a generic coupling scheme, where both coupling strengths and phase lags between and within populations are distinct, can exhibit chaotic dynamics as conjectured by Ott and Antonsen [Chaos 18, 037113 (2008)]. These chaotic mean-field dyn

Transitions from trees to cycles in adaptive flow networks

Transport networks are crucial to the functioning of natural and technological systems. Nature features transport networks that are adaptive over a vast range of parameters, thus providing an impressive level of robustness in supply. Theoretical and experimental studies have found that real-world transport networks exhibit both tree-like motifs and cycles. When the network is subject to load fluct

Chimera states in two populations with heterogeneous phase-lag

The simplest network of coupled phase-oscillators exhibiting chimera states is given by two populations with disparate intra- and inter-population coupling strengths. We explore the effects of heterogeneous coupling phase-lags between the two populations. Such heterogeneity arises naturally in various settings, for example, as an approximation to transmission delays, excitatory-inhibitory interact

Modeling of Kidney Hemodynamics : Probability-Based Topology of an Arterial Network

Through regulation of the extracellular fluid volume, the kidneys provide important long-term regulation of blood pressure. At the level of the individual functional unit (the nephron), pressure and flow control involves two different mechanisms that both produce oscillations. The nephrons are arranged in a complex branching structure that delivers blood to each nephron and, at the same time, prov

Basins of attraction for chimera states

Chimera states - curious symmetry-broken states in systems of identical coupled oscillators - typically occur only for certain initial conditions. Here we analyze their basins of attraction in a simple system comprised of two populations. Using perturbative analysis and numerical simulation we evaluate asymptotic states and associated destination maps, and demonstrate that basins form a complex tw

Characteristic Sizes of Life in the Oceans, from Bacteria to Whales

The size of an individual organism is a key trait to characterize its physiology and feeding ecology. Size-based scaling laws may have a limited size range of validity or undergo a transition from one scaling exponent to another at some characteristic size. We collate and review data on size-based scaling laws for resource acquisition, mobility, sensory range, and progeny size for all pelagic mari

Controlling chimeras

Coupled phase oscillators model a variety of dynamical phenomena in nature and technological applications. Non-local coupling gives rise to chimera states which are characterized by a distinct part of phase-synchronized oscillators while the remaining ones move incoherently. Here, we apply the idea of control to chimera states: using gradient dynamics to exploit drift of a chimera, it will attain

Vem var mest världsberömd - Cassel eller Keynes?

John Maynard Keynes brukar betraktas som världens mest berömde nationalekonom under mellankrigstiden och kanske hela 1900-talet. I början av 1920-talet lyste emellertid ett annat namn minst lika kraftigt på ekonomernas stjärnhimmel – Gustav Cassel. I denna artikel används omnämnanden av de båda ekonomerna i tidskriften The Economist som måttstock för att bedöma vem av de båda som var mest berömd p

Superdevalveringen 1982: Sverige under IMF-luppen

Sverige hade sedan länge varit en pålitlig medlem av Internationella valutafonden när den tillträdande socialdemokratiska regeringen 1982 slog till med en 16-procentig devalvering som utlöste febril aktivitet i förhållandet mellan Sverige och fonden. IMF genomförde en särskilt konsultation och devalveringen diskuterades tre gånger i fondens direktion. Såväl Sverige som IMF lyckades emellertid vänd

Hydrophobic interactions control the self-assembly of DNA and cellulose

Desoxyribosenucleic acid, DNA, and cellulose molecules self-assemble in aqueous systems. This aggregation is the basis of the important functions of these biological macromolecules. Both DNA and cellulose have significant polar and nonpolar parts and there is a delicate balance between hydrophilic and hydrophobic interactions. The hydrophilic interactions related to net charges have been thoroughl

Lung Mast Cells Have a High Constitutive Expression of Carboxypeptidase A3 mRNA That Is Independent from Granule-Stored CPA3

The mast cell granule metalloprotease CPA3 is proposed to have important tissue homeostatic functions. However, the basal CPA3 mRNA and protein expression among mast cell populations has remained poorly investigated. Using a novel histology-based methodology that yields quantitative data on mRNA and protein expression at a single-cell level, the present study maps CPA3 mRNA and protein throughout

Critical challenges in implementing sustainable transport policy in Stockholm and Gothenburg

This paper explores the mental-models of Swedish planners in order to understand the extent to which they support the ideals of sustainable transport. Focussing on three critical challenges: forecast-led versus vision-led planning; tackling congestion; and, public acceptability; the findings, drawn from in-depth interviews, demonstrate mostly advanced thinking. However, implementation can be at od

Regulation of HPV16 Early Gene Expression

Human papillomavirus type 16 (HPV16) is the most common high-risk type and isassociated with more than 50% cervical cancer cases as well as a number of headand neck cancer cases. The life cycle of HPV16 is strictly linked to celldifferentiation in the squamous epithelium with expression of the HPV16 earlygenes. The oncoproteins E6 and E7 are essential for preventing apoptosis andinducing prolifera