Manufacturing of biopharmaceuticals is a costly and time consuming process due to its inherent complexity and variability. The downstream process is the most expensive part and it involves multiple non-trivial steps. Continuous integrated manufacturing is a new concept that is encouraged by authorities. The advantages include uninterrupted operation, automation, consistent product quality, lower rManufacturing of biopharmaceuticals is a costly and time consuming process due to its inherent complexity and variability. The downstream process is the most expensive part and it involves multiple non-trivial steps. Continuous integrated manufacturing is a new concept that is encouraged by authorities. The advantages include uninterrupted operation, automation, consistent product quality, lower r

We investigated the change in terminus position between 1985 and 2015 of 17 marine-terminating glaciers that drain into Disko and Uummannaq Bays, West Greenland, by manually digitizing over 5000 individual frontal positions from over 1200 Landsat images. We find that 15 of 17 glacier termini retreated over the study period, with ~80% of this retreat occurring since 2000. Increased frequency of Lan

Eukaryotic microbes (protists) that occupy low-oxygen environments often have drastically different mitochondrial metabolism compared to their aerobic relatives. A common theme among many of anaerobic protists is the serial loss of components of the electron transport chain (ETC). Here, we discuss the diversity of the ETC across the tree of eukaryotes and review hypotheses for how ETCs are modifie

One phenomenon causing issues for language learners in the form of cross-linguistic influence (CLI) is translation ambiguity (Eddington & Tokowicz, 2013). Translation ambiguity refers to a situation where word meanings are different in a speaker’s languages. To give an example, Swedish does not lexicalize any difference between TO LEND and TO BORROW, whereas this distinction is made in English

The transport of neutrons in long beamlines at spallation neutron sources presents a unique challenge for Monte-Carlo transport calculations. This is due to the need to accurately model the deep-penetration of high-energy neutrons through meters of thick dense shields close to the source and at the same time to model the transport of low- energy neutrons across distances up to around 150 m in leng

Unfair work distribution is common in project-based learning with teams of students. One contributing factor is that students are differently skilled developers. To mitigate the differences in a course with group work, we introduced mandatory programming lab sessions. The intervention did not affect the work distribution, showing that more is needed to balance the workload. Contrary to our goal, t

As Netscape co-founder Marc Andreessen famously remarked in 2011, software is eating the world - becoming a pervasive invisible critical infrastructure. Data on the distribution of software use and development in society is scarce, but we compile results from two novel surveys to provide a fuller picture of the role software plays in the public and private sectors in Sweden, respectively. Three ou

The quark gluon plasma produced in ultrarelativistic heavy-ion collisions at the Large Hadron Collider (LHC) can be studied by measuring the modifications of jets formed by hard scattered partons which interact with the medium. We studied these modifications via angular correlations of jets with charged hadrons for jets with momenta 20

Background: A previous study has indicated poorer narrative ability during retelling in 5-year-olds with unilateral cleft lip and palate (UCLP) as a group, compared to peers without UCLP. Aim: To investigate if there are any differences between 5-year-olds with and without UCLP in narrative ability during retelling. Methods: A total of 83 children participated, 51 with UCLP and 32 without. They ha

Background: Diabetes mellitus (DM) is an established risk factor for intermittent claudication (IC) and other manifestations of atherosclerotic peripheral arterial disease. Indications for surgery in infrainguinal IC are debated, and there are conflicting reports regarding its outcomes in patients with DM. Aims of this study were to compare both short- and long-term effects on total- and cardiovas

Background: Uncomplicated urinary tract infection (UTI) causes bothersome symptoms among women and is a leading cause for antibiotic prescribing in primary healthcare (PHC). Methods: A prospective observational study in eight different PHC centres in Sweden including 192 women with symptoms of uncomplicated UTI. Questionnaires and symptom diaries were used to retrieve patient data. All urine sampl

Objective: The primary aim of this study was to compare corresponding scores between 2 existing cleft-specific patient-reported outcome measures (PROMs)—Cleft Hearing Appearance and Speech Questionnaire (CHASQ) and CLEFT-Q. The second aim of the study was to investigate patient opinion on the 2 PROMs. Design: Cross-sectional questionnaire study. Setting: Participants were recruited from a Universi

Cognitive dissonance has been studied for more than 60 years and many insightful findings have come from this research. However, some important theoretical and methodological issues are yet to be resolved, particularly regarding dissonance reduction. In this paper, we place dissonance theory in the larger framework of appraisal theories of emotion, emotion regulation, and coping. The basic premise

BACKGROUND: There is a growing interest to increase dietary fiber (DF) consumption due to the health benefits associated with this nutrient. Pulses are considered a good source of non-digestible carbohydrates. The aim of this study was to investigate the possibility of substituting semolina with chickpea flour to increase the indigestible carbohydrate content without altering the texture of the pa