Yeast-like fungi are the most common cause of fungal infections in humans. Actually, in the age of opportunistic infections and increasing resistance, development of modern antifungal agents becomes a very important challenge. This paper describes synthesis and antimicrobial assay of four naturally occurring peptide antibiotics (aurein 1.2, citropin 1.1, temporin A, uperin 3.6) and three chemicall

Författaren diskuterar problemet med den "svåra" moderna konsten.

The general objective of this thesis is to provide an understanding of the organization of Sweden's Public Dental Health Service (PDHS) and the problems it has faced, e.g. dentists’ job dissatisfaction. This is done against the background of the historical development of the Service. The thesis comprises five papers, based on two empirical studies. Questionnaires were used for both studies: respon

Cluster headache is characterised by repeated attacks of strictly unilateral pain in the orbital region associated with local autonomic symptoms or signs. The attacks are brief but of a very severe, almost excruciating intensity. For unknown reasons males are affected more often than females. Recent studies suggest that an autosomal dominant gene has a role in some families with cluster headache.

Development of autoimmune disease is the result of activation of the immune system that subsequently leads to tissue destruction. Although the clinical outcome significantly differs between autoimmune diseases, some pathogenic pathways could be shared. During the recent years, intense efforts to find the genetic factors behind development of the complex and polygenic autoimmune diseases have been

This thesis considers two different computational approaches for the analysis and synthesis of nonlinear systems. Each of these approaches is presented in a conference paper that describes parts of the theory and algorithms. Matlab commands implementing the algorithms have been developed and the manuals for these are included herein as well.

Abstract is not available

Latin hypercube sampling is suggested as a tool to improve the efficiency of different importance sampling methods for structural reliability analysis. In simple importance sampling, where the sampling centre is moved from the origin to the design point, standard Monte Carlo sampling can be replaced by Latin hypercube sampling. The efficiency improvement is then highly dependent on the choice of s

Med hjälp av elva fallstudier undersöktes hur livskvaliteten hos funktionshindrade påverkas av tillgången till ortopedtekniska (OT) hjälpmedel och professionella insatser. Resultatet tyder på att det finns stora skillnader i insatser för samma funktionshinder och därmed kostnader mellan olika personer som får OT-hjälpmedel. Den som lever ett mer aktivt liv och t ex sportar får i regel mer avancera

Ring preparations of the superficial buccal segment of the human facial vein, taken from extirpated tissue in 12 patients during neck surgery, were studied in vitro. The vein developed a maintained intrinsic myogenic tone in response to passive stretch and was supplied with alpha- as well as beta-adrenoceptors, both of which could be influenced by transmural nerve stimulation (TNS) and noradrenali

The single-dose effect of formoterol racemate and enantiomers on bronchodilatation up to 24 h was determined. Forty-six reversible asthmatic patients were randomised to this double blind, crossover study. Formoterol was inhaled by nebulizer (HaloLite(R)); 4.5 and 36 mug of the racemate (rac-formoterol), 2.25 and 18 mug of (R;R)-formoterol, 18 mug of (S;S)-formoterol, or placebo. Airway and systemi

A nasal spray formulation containing an extract of Artemisia abrotanum L. was developed for therapeutic use in patients with allergic rhinitis and other upper airway disorders. The nasal spray preparation used contains a mixture of essential oils (4 mg/ml) and flavonols (2.5 mug/ml), of which some components have been shown to possess antiinflammatory, expectorant, spasmolytic as well as antisepti