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Structural and Functional Studies of the Wilms' Tumour 1 Protein (WT1) in Interaction with Nucleic acids

The WT1 protein, a product of the Wilms’ tumour 1 gene (WT1) is a zinc finger transcription factor implicated in a number of cellular processes particularly involved in the development of the urogenital system. Mutations in this gene have been implicated in abnormal development of the urogenital system resulting in syndromes such as the Denys-Drash, WAGR and Frasier and in the childhood kidney mal

Segregation of Women in Public Space in Iran

As part of a systematic endeavor to Islamize the society, Iranian Islamic government has bestowed efforts to create gender-segregated public urban spaces. The gender segregation was formally enforced in public places such as schools, sport halls, swimming pools, transportation facilities, etc. in last three decades. The most recent effort of the government includes “women-only parks”, claimed to b

A 0.8V, 7uA, rail-to-rail input/output, constant Gm operational amplifier in standard digital 0.18um CMOS

A two-stage amplifier, operational at 0.8V and drawing 7/spl mu/A, has been integrated in a standard digital 0.18/spl mu/m CMOS process. Rail-to-rail operations at the input are enabled by complementary transistor pairs with g/sub m/ control. The efficient rail-to-rail output stage is biased in class AB. The measured DC gain of the amplifier is 75dB, and the unity-gain frequency is 870kHz with a 1

Receivers of (dis)trust: Administrators in bankruptcy

Analyses of economic actions often proceed from a consideration of how trust serves as a basis for the interaction of economic agents. A bankruptcy entails a breach of the relations of trust in an economic network. Receivers are the lawyers appointed by Swedish courts to investigate and ultimately resolve bankrupts disputes. The article demonstrates how the manner in which receivers characterise t

Pituitary adenylate cyclase activating peptide: a neuropeptide in the sensory nervous system.

This thesis deals with the expression of pituitary adenylate cyclase activating peptide (PACAP) in sensory C-type cells and primary afferent fibres and its possible role in nociceptive transmission. PACAP-expression, -release, -synthesis and -function were investigated in a series of measurements using immunocytochemistry, radioimmunoassay, in situ hybridization histochemistry, Northern blot, elec